Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Soorin Yim"'
Autor:
Méabh MacMahon, Woochang Hwang, Soorin Yim, Eoghan MacMahon, Alexandre Abraham, Justin Barton, Mukunthan Tharmakulasingam, Paul Bilokon, Vasanthi Priyadarshini Gaddi, Namshik Han
Publikováno v:
Informatics in Medicine Unlocked, Vol 43, Iss , Pp 101387- (2023)
Background: Drug repurposing provides an opportunity to redeploy drugs, which are already tested for safety or approved for use in humans, for the treatment of diseases distinct from their primary indication. For example, the repurposing of dexametha
Externí odkaz:
https://doaj.org/article/43294507f5c0413ca08596e23b167d74
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Cancer immunotherapy targets the interplay between immune and cancer cells. In particular, interactions between cytotoxic T lymphocytes (CTLs) and cancer cells, such as PD-1 (PDCD1) binding PD-L1 (CD274), are crucial for cancer cell clearance. Howeve
Externí odkaz:
https://doaj.org/article/925e6ba5742747f8851d747d578a5061
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S10, Pp 45-53 (2019)
Abstract Background Computational analysis of complex diseases involving multiple organs requires the integration of multiple different models into a unified model. Different models are often constructed in heterogeneous formats. Thus, the integratio
Externí odkaz:
https://doaj.org/article/6fa0c755110a406cafebfbad9c799af3
Autor:
Hasun Yu, Jinmyung Jung, Seyeol Yoon, Mijin Kwon, Sunghwa Bae, Soorin Yim, Jaehyun Lee, Seunghyun Kim, Yeeok Kang, Doheon Lee
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract In silico network-based methods have shown promising results in the field of drug development. Yet, most of networks used in the previous research have not included context information even though biological associations actually do appear i
Externí odkaz:
https://doaj.org/article/e86ff0bfc6124139b31a2f0eadf7d511
Cancer immunotherapy works through the interplay between immune and cancer cells. Particularly, interactions between cytotoxic T lymphocytes (CTLs) and cancer cells, such as PDCD1 (PD-1) and CD274 (PD-L1), are crucial for removing cancer cells. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81a4f16541595c9c5ddfc250e7a0373c
https://doi.org/10.1101/2022.03.03.482805
https://doi.org/10.1101/2022.03.03.482805
Publikováno v:
Recent Advances in Biological Network Analysis ISBN: 9783030571726
Network-based in silico approaches have played important roles in drug development. Network analysis is advantageous to identifying both direct (close) and indirect (distant) relationships among biological entities comprehensively. There have been ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf8efe71605cd35d92d75374c0791259
https://doi.org/10.1007/978-3-030-57173-3_8
https://doi.org/10.1007/978-3-030-57173-3_8
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S10, Pp 45-53 (2019)
BMC Bioinformatics
BMC Bioinformatics
Background Computational analysis of complex diseases involving multiple organs requires the integration of multiple different models into a unified model. Different models are often constructed in heterogeneous formats. Thus, the integration of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab6c500dbd9ad5ebd669359e929e7ad
https://doi.org/10.1186/s12859-019-2812-7
https://doi.org/10.1186/s12859-019-2812-7
Publikováno v:
BMC Systems Biology, Vol 12, Iss S1, Pp 111-122 (2018)
BMC Systems Biology
BMC Systems Biology
Background Signaling pathways can be reconstructed by identifying ‘effect types’ (i.e. activation/inhibition) of protein-protein interactions (PPIs). Effect types are composed of ‘directions’ (i.e. upstream/downstream) and ‘signs’ (i.e. p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd5fdbc46a656b7bbfcb7cf8912a5ab
https://doi.org/10.1186/s12918-018-0535-4
https://doi.org/10.1186/s12918-018-0535-4
Publikováno v:
BMC Systems Biology
BMC Systems Biology, Vol 12, Iss 1, Pp 1-11 (2018)
BMC Systems Biology, Vol 12, Iss 1, Pp 1-11 (2018)
Background Muscle atrophy, an involuntary loss of muscle mass, is involved in various diseases and sometimes leads to mortality. However, therapeutics for muscle atrophy thus far have had limited effects. Here, we present a new approach for therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e26bff4a25206972bc07129a8b4a5d
http://europepmc.org/articles/PMC5838966
http://europepmc.org/articles/PMC5838966
Autor:
Hasun Yu, Jinmyung Jung, Seyeol Yoon, Mijin Kwon, Sunghwa Bae, Soorin Yim, Jaehyun Lee, Seunghyun Kim, Yeeok Kang, Doheon Lee
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-1 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-1 (2018)
In silico network-based methods have shown promising results in the field of drug development. Yet, most of networks used in the previous research have not included context information even though biological associations actually do appear in the spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9638f0b6789b9ea20631709f6063139
http://europepmc.org/articles/PMC5840328
http://europepmc.org/articles/PMC5840328