Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Soon-Kyoung Kwon"'
Autor:
Aree Moon, Soon-Kyoung Kwon
Publikováno v:
Archives of Pharmacal Research. 28:391-394
The allylthio group of allicin and other organosulfur compounds, isolated from garlic, is considered a pharmacophore, and a key structure component of the molecule, which affords biological activities. In the foregoing studies, various 3-alkoxy-6-all
Autor:
Hea-Soon Shin, Soon-Kyoung Kwon
Publikováno v:
Archives of Pharmacal Research. 26:351-357
Five kinds of allylthiopyridazine derivatives were synthesized and their chemoprotective activities examined in rats exposed to aflatoxin B1-toxicant. Rats were pretreated with five allylthiopyridazine derivatives at daily oral doses of 50 mg/kg for
Publikováno v:
Archives of Pharmacal Research. 22:44-47
Three 1,2-benzothiazine derivatives were synthesized, and their analgesic/anti-inflammatory efficacy and their effects on gastric irritation were evaluated. Among the three compounds, 39 exhibited the most potent analgesic action, but the effect was
Publikováno v:
Bulletin of the Korean Chemical Society. 23:1836-1838
By the application of these methods, 1,2-benzothi-azine derivatives with 3-aminohydantoin moiety were pre-pared. Here, we report the synthesis of several new 3-aminohydantoinyl-1,2-benzothiazine derivatives and pro-pose an another mechanism of the cy
Publikováno v:
Archives of Pharmacal Research. 16:322-326
For the development of new antiinflammatory and analgesic drugs, new 5-alkylthio (or sulfonyl) methyl-5-m-methoxyphenylhydantoin-3-acetic acid derivatives(alkyl; ethyl, propyl, butyl) were prepared. The 5,5-disubstituted hydantoins which were used as
Autor:
Myung-Sook Park, Soon Kyoung Kwon
Publikováno v:
ChemInform. 28
Autor:
Myoung-suk Park, Soon-Kyoung Kwon
Publikováno v:
Archives of Pharmacal Research. 15:251-255
A number of 4-hydroxy-2H (or alkyl)-N-(3-aralkyl-2-thio-1-hydantoinyl)-1,2-benzothiazine-3-carboxamide 1,1-dioxides were synthesized through the reaction of 4-hydroxy-2H (or alkyl)-1,2-benzothiazine-3-carboxylic methyl ester 1,1-dioxide and 1-amino-2
Autor:
Soon-Kyoung Kwon, Young-Nam Park
Publikováno v:
Archives of Pharmacal Research. 23:329-331
4-(p-Chlorophenyl)tetralone (6) and 7-chloro-5-(p-chlorophenyl)tetralone (9) are key intermediates for the development of benzazepinone derivative haftens. These compounds could be synthesized from 4-phenyltetralone derivatives by triflic acid cataly
Publikováno v:
International Journal of Oncology.
Numerous studies have revealed the chemopreventive and hepatoprotective activities of dietary and synthetic organosulfur compounds. We previously showed that synthetic allylthiopyridazine derivatives, designated as K compounds, induced apoptosis in S
Publikováno v:
ChemInform. 34
By the application of these methods, 1,2-benzothi-azine derivatives with 3-aminohydantoin moiety were pre-pared. Here, we report the synthesis of several new 3-aminohydantoinyl-1,2-benzothiazine derivatives and pro-pose an another mechanism of the cy