Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Soon-Jae Park"'
Publikováno v:
Journal of Animal Science and Technology, Vol 63, Iss 2, Pp 272-280 (2021)
Cumulus-oocyte complexes (COCs), which contain immature oocytes, are matured in vitro for in vitro embryo production. Oocyte and cumulus cells are then separated using hyaluronidase. To date, there have only been a few reported cases of the toxic
Externí odkaz:
https://doaj.org/article/4d35c4499bd54c408f39b8b1dab2f304
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185074 (2017)
Alpha 1-antitrypsin (A1AT) is a serine protease inhibitor that mainly inhibits neutrophil elastase in the lungs. A variant of A1AT at the P1 position with methionine 358 to arginine (A1AT-Pittsburgh) is a rapid inhibitor of thrombin with greatly dimi
Externí odkaz:
https://doaj.org/article/263f256a148d44738e3625d91ad058e9
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159451 (2016)
Here, we demonstrate that a metal ion binding motif could serve as an efficient and robust tool for site-specific conjugation strategy. Cysteine-containing metal binding motifs were constructed as single repeat or tandem repeat peptides and their met
Externí odkaz:
https://doaj.org/article/40a868a6e5e44187b2c48215e00de12c
Publikováno v:
Korean Journal of Acupuncture. 34:109-115
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9ca119ab7228f8a11dbe9babc250029
https://doi.org/10.14406/acu.2017.014
https://doi.org/10.14406/acu.2017.014
Publikováno v:
Glycoconjugate Journal. 33:201-208
Glycosylation affects the circulatory half-lives of therapeutic proteins. However, the effects of an additional N-glycosylation in the unstructured region or the loop region of alpha-1 antitrypsin (A1AT) on the circulatory half-life of the protein ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae2b28cc400d27888f65b9a65bb1152
https://doi.org/10.1007/s10719-016-9657-3
https://doi.org/10.1007/s10719-016-9657-3
Autor:
Hye-Shin Chung, Yeon Hee Park, Sunbae Lee, Seol-Hee Kim, Ji-Yeon Kim, Hee Kyung Ahn, Young-Hyuck Im, Jin Seok Ahn, Soon Jae Park
Publikováno v:
Journal of Clinical Oncology. 38:3551-3551
3551 Background: ALT-P7 is an antibody-drug conjugate, in which two molecules of monomethyl auristatin E (MMAE) are site-specifically conjugated to a cysteine-containing peptide motif of trastuzumab variant. This is the first-in-human study evaluatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d063890367258860332f123a1f22f32
https://doi.org/10.1200/jco.2020.38.15_suppl.3551
https://doi.org/10.1200/jco.2020.38.15_suppl.3551
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 9, p e0185074 (2017)
PLoS ONE, Vol 12, Iss 9, p e0185074 (2017)
Alpha 1-antitrypsin (A1AT) is a serine protease inhibitor that mainly inhibits neutrophil elastase in the lungs. A variant of A1AT at the P1 position with methionine 358 to arginine (A1AT-Pittsburgh) is a rapid inhibitor of thrombin with greatly dimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e5f979ea222f11af28ce6078043299
https://doi.org/10.1371/journal.pone.0185074
https://doi.org/10.1371/journal.pone.0185074
Autor:
William J. Kohr, Tadeusz Wilusz, James R. Cook, Michael Ranjbar, Jacek Otlewski, Sabiha Qasim, Nicholas Warne, Theresa L. Bigler, Anna Wieczorek, Wenlei Zhang, Tiao-Yin Lin, Michael Laskowski, Izydor Apostol, Harry Whatley, Richard Wynn, Tomoko Komiyama, Stephen M. Lu, Misao Tashiro, Maciej Wieczorek, Michio Ogawa, Soon Jae Park, Wojciech Ardelt, Wuyuan Lu, M. A. Qasim, Stephen Anderson, I. Kato, Clyde A. Kelly, Yi Wen Chiang, Michael N.G. James
Publikováno v:
Proceedings of the National Academy of Sciences. 98:1410-1415
An additivity-based sequence to reactivity algorithm for the interaction of members of the Kazal family of protein inhibitors with six selected serine proteinases is described. Ten consensus variable contact positions in the inhibitor were identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da2f63f2dc3c13d0d9ed6a9130ee32c
https://doi.org/10.1073/pnas.98.4.1410
https://doi.org/10.1073/pnas.98.4.1410
Autor:
Kyung Jin Lee, Soon Jae Park, Ohsuk Kwon, Sang Mee Lee, Jin Young Kim, Jin Young Gil, Hye-Shin Chung, Doo-Byoung Oh
Publikováno v:
Glycoconjugate journal. 30(5)
Human alpha-1-antitrypsin (α1AT) is a glycoprotein with protease inhibitor activity protecting tissues from degradation. Patients with inherited α1AT deficiency are treated with native α1AT (nAT) purified from human plasma. In the present study, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898e60ffbf20e7f71af02846c38c8f62
https://pubmed.ncbi.nlm.nih.gov/23065139
https://pubmed.ncbi.nlm.nih.gov/23065139
Autor:
Richard Wynn, Wuyuan Lu, Soon Jae Park, Theresa L. Bigler, Misao Tashiro, Michael Laskowski, Maciej Wieczorek
Publikováno v:
Protein science : a publication of the Protein Society. 2(5)
In the association of serine proteinases with their cognate substrates and inhibitors an important interaction is the fitting of the P1 side chain of the substrate or inhibitor into a preformed cavity of the enzyme called the S1 pocket. In turkey ovo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98c663aec950c1add2afb2271866a93f
https://pubmed.ncbi.nlm.nih.gov/8495199
https://pubmed.ncbi.nlm.nih.gov/8495199