Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Soon Jin Park"'
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Tanshinone IIA suppresses FcεRI-mediated mast cell signaling and anaphylaxis by activation of the Sirt1/LKB1/AMPK pathway
Autor: Youn Ju Lee, Yifeng Deng, Dong Young Kim, Fansi Jin, Jung-Ae Kim, Ju Hye Yang, Kun Ho Son, Hyeun Wook Chang, Jae-Hoon Chang, Soon Jin Park, Makoto Murakami, Xian Li
Publikováno v: Biochemical Pharmacology. 152:362-372
AMP-activated protein kinase (AMPK) and its upstream mediators liver kinase B1 (LKB1) and sirtuin 1 (Sirt1) are generally known as key regulators of metabolism. We have recently reported that the AMPK pathway negatively regulates mast cell activation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31809d744a5c612f1cdac4ab179e1b4
https://doi.org/10.1016/j.bcp.2018.04.015
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5
Saucerneol F inhibits tumor necrosis factor-α and IL-6 production by suppressing Fyn-mediated pathways in FcεRI-mediated mast cells
Autor: Jong Keun Son, Jung-Hye Choi, Soon Jin Park, Young-Chae Chang, Yue Lu, Donggen Piao, Hyeun Wook Chang, Seung-Hyun Jung, Xian Li, Makoto Murakami, Guang Hsuan Chao, Haiyan Zhang, Cheorl-Ho Kim
Publikováno v: Food and Chemical Toxicology. 59:696-702
The aim of this study was to investigate the effect of saucerneol F (SF) on the productions of the pro-inflammatory cytokines, TNF-α and IL-6, in IgE/Ag-induced mouse bone marrow-derived mast cells (BMMCs). SF dose-dependently suppressed the transcr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7327b4b86f626219e0ab3fc8a646657
https://doi.org/10.1016/j.fct.2013.06.056
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6
Citreorosein, a naturally occurring anthraquinone derivative isolated from Polygoni cuspidati radix, attenuates cyclooxygenase-2-dependent prostaglandin D2 generation by blocking Akt and JNK pathways in mouse bone marrow-derived mast cells
Autor: Soon Jin Park, Hyeun Wook Chang, Yurndong Jahng, Ying Li, Seung Ho Lee, Kyoung Hwangbo, Makoto Murakami, Cheorl-Ho Kim, Xian Li, Jong-Keun Son, Seok-Jong Suh, Yue Lu, Seung-Lark Hwang
Publikováno v: Food and Chemical Toxicology. 50:913-919
In this study, we examined the effects of citreorosein (CIT), an anthraquinone component of Polygoni cuspidati radix (P. cuspidati, Polygonaceae), on cyclooxygenase (COX)-2 dependent prostaglandin (PG)D2 generation in mast cells, central effector cel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2feca6d423025efecc90ea69cb8d687f
https://doi.org/10.1016/j.fct.2011.11.046
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7
Pimaric acid from Aralia cordata has an inhibitory effect on TNF-α-induced MMP-9 production and HASMC migration via down-regulated NF-κB and AP-1
Autor: Cheorl-Ho Kim, Soon Jin Park, Young-Guk Park, Young-Choon Lee, Tae-Wook Chung, Jong-Keun Son, Choong-Hwan Kwak, Sung-Soo Park, Seok-Jong Suh, Meijuan Cheeeei, Young-Chae Chang, Chang-Seob Seo, Hyeun Wook Chang
Publikováno v: Chemico-biological interactions. 199(2)
Many studies have indicated that activation of matrix metalloproteinase (MMP)-9 and smooth muscle cell (SMC) migration are involved in neointimal formation and atherosclerosis. In this study, we revealed that pimaric acid (PiMA) purified from Aralia
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633292da3def86b98ad69b2ce147acd3
https://pubmed.ncbi.nlm.nih.gov/22705379
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