Zobrazeno 1 - 10
of 417
pro vyhledávání: '"Soon B"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Natural products and herbal medicine have been widely used in drug discovery for treating infectious diseases. Recent outbreak of COVID-19 requires various therapeutic strategies. Here, we used YSK-A, a mixture of three herbal components Bos
Externí odkaz:
https://doaj.org/article/6b34c78f4b4745c08b545842f7295729
Autor:
Trang T. X. Huynh, Thuy X. Pham, Gun-Hee Lee, Jae-Bong Lee, Sung-Geun Lee, Dongseob Tark, Yun-Sook Lim, Soon B. Hwang
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19). SARS-CoV-2 propagation is mediated by the protein interaction between viral proteins and host cells. Tyrosine kinase
Externí odkaz:
https://doaj.org/article/5a48daac5d894da284da852e0950ef88
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13414 (2021)
African swine fever virus (ASFV) is a highly contagious virus that causes severe hemorrhagic viral disease resulting in high mortality in domestic and wild pigs, until few antiviral agents can inhibit ASFV infections. Thus, new anti-ASFV drugs need t
Externí odkaz:
https://doaj.org/article/1e096b15e2cd4d9ab63cee8dfcf6926f
Autor:
Jiwon Choi, Jun Seop Yun, Hyeeun Song, Yong-Keol Shin, Young-Hoon Kang, Palinda Ruvan Munashingha, Jeongyeon Yoon, Nam Hee Kim, Hyun Sil Kim, Jong In Yook, Dongseob Tark, Yun-Sook Lim, Soon B. Hwang
Publikováno v:
Molecules, Vol 26, Iss 12, p 3592 (2021)
African swine fever virus (ASFV) causes a highly contagious and severe hemorrhagic viral disease with high mortality in domestic pigs of all ages. Although the virus is harmless to humans, the ongoing ASFV epidemic could have severe economic conseque
Externí odkaz:
https://doaj.org/article/a2188459c33244ccad12c0afbaa8a58d
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract The life cycle of hepatitis C virus (HCV) is highly dependent on host proteins for virus propagation. By transcriptome sequencing analysis, we identified host genes that were highly differentially expressed in HCV-infected cells. Of these ca
Externí odkaz:
https://doaj.org/article/9de472c49b474a6891d23ce602b6f2f4
Autor:
Kidong Son, Tram T. T. Nguyen, Jae-Woong Choi, Long V. Pham, Trang T. D. Luong, Yun-Sook Lim, Soon B. Hwang
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Hepatitis C virus (HCV) is a leading cause of chronic liver disease affecting over 170 million people worldwide. Chronic infection with HCV progresses to liver fibrosis, cirrhosis, and hepatocellular carcinoma. HCV exploits host cellular factors for
Externí odkaz:
https://doaj.org/article/bd694b4530934371a19a1ab49e03da03
Autor:
Saehong Min, Yun-Sook Lim, Dongjo Shin, Chorong Park, Jae-Bong Park, Seungtaek Kim, Marc P. Windisch, Soon B. Hwang
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Abl is a central regulator of multiple cellular processes controlling actin dynamics, proliferation, and differentiation. Here, we showed that knockdown of Abl impaired hepatitis C virus (HCV) propagation. Treatment of Abl tyrosine kinase-specific in
Externí odkaz:
https://doaj.org/article/7d55f83173bb49e5aaa9993b879c9ecb
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132839 (2015)
Hepatitis C virus (HCV) usurps host cellular lipid metabolism for production of infectious virus particles. Recently, we have screened a siRNA library targeting host factors that control lipid metabolism and lipid droplet (LD) formation in cell cultu
Externí odkaz:
https://doaj.org/article/fd7ddf2665214432811fd9831024dc97
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68170 (2013)
Hepatitis C virus (HCV) is highly dependent on cellular factors for its own propagation. By employing tandem affinity purification method, we identified pyruvate carboxylase (PC) as a cellular partner for NS5A protein. NS5A interacted with PC through
Externí odkaz:
https://doaj.org/article/59fb8e7fe2ca4143a2e1c2d0d3131f54
Autor:
Jihye Lee, Seri Lim, Sang-Min Kang, Saehong Min, Kidong Son, Han Sol Lee, Eun Mee Park, Huong T T Ngo, Huong T L Tran, Yun-Sook Lim, Soon B Hwang
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39366 (2012)
Saponins are a group of naturally occurring plant glycosides which possess a wide range of pharmacological properties, including anti-tumorigenic and antiviral activities. To investigate whether saponin has anti-hepatitis C virus (HCV) activity, we e
Externí odkaz:
https://doaj.org/article/c2baf151dc4e4d52b936fe3d7e998205