Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Soon‐Chan Kim"'
Autor:
Soon-Chan Kim, Min Jung Kim, Ji Won Park, Young-Kyoung Shin, Seung-Yong Jeong, Sungwan Kim, Ja-Lok Ku
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Cellular and molecular dynamics of human cells are constantly affected by gravity. Alteration of the gravitational force disturbs the cellular equilibrium, which might modify physiological and molecular characteristics. Nevertheless, biologi
Externí odkaz:
https://doaj.org/article/f5869a34131e43979d8b24a4ba595a61
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Sarcomas, malignant tumors from mesenchymal tissues, exhibit poor prognosis despite advancements in treatment modalities such as surgery, radiotherapy, and chemotherapy, with doxorubicin being a cornerstone treatment. Resistance to doxorubic
Externí odkaz:
https://doaj.org/article/21f890e2a3414a9498dfc915e001c148
Autor:
Sarah S. Wang, Madison L. Hall, EunJung Lee, Soon-Chan Kim, Neha Ramesh, Sang Hyub Lee, Jin-Young Jang, Richard J. Bold, Ja-Lok Ku, Chang-Il Hwang
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109414- (2024)
Summary: In pancreatic ductal adenocarcinoma (PDAC), no recurrent metastasis-specific mutation has been found, suggesting that epigenetic mechanisms, such as DNA methylation, are the major contributors of late-stage disease progression. Here, we perf
Externí odkaz:
https://doaj.org/article/b585b1d868174aa89f6764d299282f5f
Autor:
Soon-Chan Kim, Young-Eun Cho, Young-Kyoung Shin, Hyeon Jong Yu, Tamrin Chowdhury, Sojin Kim, Kyung Sik Yi, Chi-Hoon Choi, Sang-Hoon Cha, Chul-Kee Park, Ja-Lok Ku
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-15 (2023)
Abstract Glioblastoma (GBM) is the most lethal intracranial tumor. Sequencing technologies have supported personalized therapy for precise diagnosis and optimal treatment of GBM by revealing clinically actionable molecular characteristics. Although a
Externí odkaz:
https://doaj.org/article/d8555ba98b0944cc98c9445c006e11d0
Autor:
Nahyun Jeong, Soon-Chan Kim, Ji Won Park, Seul Gi Park, Ki-Hoan Nam, Ja Oh Lee, Young-Kyoung Shin, Jeong Mo Bae, Seung-Yong Jeong, Min Jung Kim, Ja-Lok Ku
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-15 (2022)
Abstract Multifocal colorectal cancer (CRC) comprises both clonally independent primary tumors caused by inherited predisposition and clonally related tumors mainly due to intraluminal spreading along an intact basement membrane. The distinction betw
Externí odkaz:
https://doaj.org/article/82d38148d7234671be9ddd099e656ac2
Autor:
Ha-Young Seo, Soon-Chan Kim, Woo-lee Roh, Young-Kyoung Shin, Soyeon Kim, Dong-Wan Kim, Tae Min Kim, Ja-Lok Ku
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Malignant pleural effusion (MPE) is an independent determinant of poor prognostic factor of non-small cell lung cancer (NSCLC). The course of anchorage independent growth within the pleural cavity likely reforms the innate molecular characte
Externí odkaz:
https://doaj.org/article/839f69a5d6494ccfa41411e18c14f807
Autor:
Soon-Chan Kim, Young-Eun Cho, Young-Kyoung Shin, Hyeon Jong Yu, Tamrin Chowdhury, Sojin Kim, Kyung Sik Yi, Chi-Hoon Choi, Sang-Hoon Cha, Chul-Kee Park, Ja-Lok Ku
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/06079cf06b3246b991fb303c4619e453
Autor:
Myoung-Hyun Song, Ji Won Park, Min Jung Kim, Young-Kyoung Shin, Soon-Chan Kim, Seung-Yong Jeong, Ja-Lok Ku
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 152, Iss , Pp 113260- (2022)
Organoid culture technique has been taking center stage as a next-generation ex-vivo model due to advancement of stem cell research techniques. The importance of the laboratory-based ex vivo model has increasingly been recognized for recapitulating h
Externí odkaz:
https://doaj.org/article/89644fbcad814138af858588139dc1a9
Autor:
Jieun Seo, Cho‐Rong Lee, Jin Chul Paeng, Hyun W. Kwon, Duckgue Lee, Soon‐Chan Kim, Jaeseok Han, Ja‐Lok Ku, Jong Hee Chae, Byung Chan Lim, Murim Choi
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 8, Pp 1443-1449 (2020)
Abstract The clinical phenotype linked with mutations in ABCB1, encoding P‐glycoprotein, has never been reported. Here, we describe twin sisters with biallelic mutations in ABCB1 who showed recurrent reversible encephalopathy accompanied by acute f
Externí odkaz:
https://doaj.org/article/bfcd5c10bf4c43c1a7cf9258d3054069
Autor:
Soon‐Chan Kim, Ji Won Park, Ha‐Young Seo, Minjung Kim, Jae‐Hyeon Park, Ga‐Hye Kim, Ja Oh Lee, Young‐Kyoung Shin, Jeong Mo Bae, Bon‐Kyoung Koo, Seung‐Yong Jeong, Ja‐Lok Ku
Publikováno v:
Advanced Science, Vol 9, Iss 5, Pp n/a-n/a (2022)
Abstract Intratumor heterogeneity (ITH) stands as one of the main difficulties in the treatment of colorectal cancer (CRC) as it causes the development of resistant clones and leads to heterogeneous drug responses. Here, 12 sets of patient‐derived
Externí odkaz:
https://doaj.org/article/7e6c15caffa34284985a203c539de15a