Response-Adaptive Surgical Timing in neoadjuvant immunotherapy demonstrates enhanced pathologic treatment response in Head and Neck Squamous Cell Carcinoma.

Autor: Mastrolonardo EV; Thomas Jefferson University, Philadelphia, PA, United States., Nunes KL; Thomas Jefferson University, Philadelphia, PA, United States., Llerena P; Thomas Jefferson University, Philadelphia, PA, United States., Nikitina A; BostonGene Corporation, Waltham, MA, United States., Sobol A; BostonGene Corporation, Waltham, Massachusetts, United States., Scott ER; Thomas Jefferson University, Philadelphia, PA, United States., Tuluc M; Thomas Jefferson University, Philadelphia, Pennsylvania, United States., Davitt CJH; BostonGene Corporation, Waltham, Massachusetts, United States., Scher J; BostonGene Corporation, Waltham, MA, United States., Tekumalla S; Thomas Jefferson University, Philadelphia, PA, United States., Mann D; Thomas Jefferson University, Philadelphia, PA, United States., Henao C; Thomas Jefferson University, Philadelphia, PA, United States., Jegede V; Thomas Jefferson University, Philadelphia, PA, United States., Gargano S; Thomas Jefferson University, Philadelphia, Pennsylvania, United States., Harshyne LA; Thomas Jefferson University, Philadelphia, PA, United States., Alnemri A; Thomas Jefferson University Hospital, Philadelphia, PA, United States., Tyshevich A; BostonGene Corporation, Waltham, MA, United States., Kushnarev V; BostonGene Corporation, Waltham, MA, United States., Chasse M; BostonGene Corporation, Waltham, MA, United States., Sookiasian D; BostonGene Corporation, Waltham, MA, United States., Axelrod R; Thomas Jefferson University, Philadelphia, PA, United States., Zhan T; Thomas Jefferson University, Philadelphia, United States., Leiby BE; Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, PA, United States., Old M; The Ohio State University, Columbus, OH, United States., Seim N; The Ohio State University, Columbus, OH, United States., Mahoney MG; Thomas Jefferson University, Philadelphia, PA, United States., Martinez-Outschoorn U; Thomas Jefferson University, Philadelphia, PA, United States., Cognetti DM; Thomas Jefferson University, Philadelphia, PA, United States., Curry JM; Thomas Jefferson University, Philadelphia, PA, United States., Prendergast G; Lankenau Institute for Medical Research, Wynnewood, PA, United States., Argiris A; Thomas Jefferson University Hospital, Philadelphia, PA, United States., South AP; Thomas Jefferson University, Philadelphia, PA, United States., Linnenbach AJ; Thomas Jefferson University, Philadelphia, United States., Johnson JM; Thomas Jefferson University, Philadelphia, PA, United States., Luginbuhl AJ; Thomas Jefferson University, Philadelphia, PA, United States.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 Nov 25. Date of Electronic Publication: 2024 Nov 25.

Molecular characterization of precise in vivo targeted gene integration in human cells using AAVHSC15.

Autor: Chen HM; Homology Medicines Inc., Bedford, Massachusetts, United States of America., Resendes R; Homology Medicines Inc., Bedford, Massachusetts, United States of America., Ghodssi A; Homology Medicines Inc., Bedford, Massachusetts, United States of America., Sookiasian D; Homology Medicines Inc., Bedford, Massachusetts, United States of America., Tian M; Homology Medicines Inc., Bedford, Massachusetts, United States of America., Dollive S; Homology Medicines Inc., Bedford, Massachusetts, United States of America., Adamson-Small L; Homology Medicines Inc., Bedford, Massachusetts, United States of America., Avila N; Homology Medicines Inc., Bedford, Massachusetts, United States of America., Tazearslan C; Homology Medicines Inc., Bedford, Massachusetts, United States of America., Thompson JF; Homology Medicines Inc., Bedford, Massachusetts, United States of America., Ellsworth JL; Homology Medicines Inc., Bedford, Massachusetts, United States of America., Francone O; Homology Medicines Inc., Bedford, Massachusetts, United States of America., Seymour A; Homology Medicines Inc., Bedford, Massachusetts, United States of America., Wright JB; Homology Medicines Inc., Bedford, Massachusetts, United States of America.

Publikováno v: PloS one [PLoS One] 2020 May 26; Vol. 15 (5), pp. e0233373. Date of Electronic Publication: 2020 May 26 (Print Publication: 2020).

Nuclease-free precise genome editing corrects MECP2 mutations associated with Rett syndrome.

Autor: Bijlani, Swati, Pang, Ka Ming, Bugga, Lakshmi V., Rangasamy, Sampath, Narayanan, Vinodh, Chatterjee, Saswati

Publikováno v: Frontiers in Genome Editing; 2024, p1-16, 16p

Gata3 is required in late proneurosensory development for proper sensory cell formation and organization.

Autor: Blinkiewicz PV; Department of Biological Sciences, Western Michigan University, Kalamazoo, MI, USA., Long MR; Department of Biological Sciences, Western Michigan University, Kalamazoo, MI, USA., Stoner ZA; Department of Biological Sciences, Western Michigan University, Kalamazoo, MI, USA. Zach.stoner@nih.gov.; Section On Sensory Cell Regeneration and Development, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, 20892, USA. Zach.stoner@nih.gov., Ketchum EM; Department of Biological Sciences, Western Michigan University, Kalamazoo, MI, USA., Sheltz-Kempf SN; Department of Biological Sciences, Western Michigan University, Kalamazoo, MI, USA., Duncan JS; Department of Biological Sciences, Western Michigan University, Kalamazoo, MI, USA. Dunca105@umn.edu.; Department of Biomedical Sciences, Western Michigan School of Medicine, Kalamazoo, MI, USA. Dunca105@umn.edu.; Department of Neurology, University of Minnesota, Minneapolis, MN, USA. Dunca105@umn.edu.

Publikováno v: Scientific reports [Sci Rep] 2023 Aug 03; Vol. 13 (1), pp. 12573. Date of Electronic Publication: 2023 Aug 03.

Betaine-homocysteine S-methyltransferase deficiency causes increased susceptibility to noise-induced hearing loss associated with plasma hyperhomocysteinemia.

Autor: Partearroyo, Teresa, Murillo-Cuesta, Silvia, Vallecillo, Néstor, Bermúdez-Muñoz, Jose M., la Rosa, Lourdes Rodríguez-de, Mandruzzato, Giacomo, Celaya, Adelaida M., Zeisel, Steven H., Pajares, María A., Varela-Moreiras, Gregorio, Varela-Nieto, Isabel

Publikováno v: FASEB Journal; May2019, Vol. 33 Issue 5, p5942-5956, 15p