Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sookhee Bang"'
Publikováno v:
IBRO Neuroscience Reports, Vol 17, Iss , Pp 423-430 (2024)
Introduction: Neurofibrillary tangles (NFTs) are composed of hyperphosphorylated forms of microtubule-associated protein tau (Tau), which is responsible for neurodegeneration in Alzheimer’s disease (AD). The hippocampal region has been a major focu
Externí odkaz:
https://doaj.org/article/b1ad43a822624b44b8a40b174895f499
Autor:
Steven E. Arnold, Irwin Lucki, Bethany R. Brookshire, Gregory C. Carlson, Caroline A. Browne, Hala Kazi, Sookhee Bang, Bo-Ran Choi, Yong Chen, Mary F. McMullen, Sangwon F. Kim
Publikováno v:
Neurobiology of Disease, Vol 67, Iss , Pp 79-87 (2014)
Insulin resistance and other features of the metabolic syndrome are increasingly recognized for their effects on cognitive health. To ascertain mechanisms by which this occurs, we fed mice a very high fat diet (60% kcal by fat) for 17 days or a moder
Externí odkaz:
https://doaj.org/article/0f2c69c70c3044f080016390788f6f49
Autor:
Sookhee Bang, Sung Ill Jang, Su Yeon Lee, Yi-Yong Baek, Jieun Yun, Soo Jin Oh, Chang Woo Lee, Eun Ae Jo, Kun Na, Sugeun Yang, Don Haeng Lee, Dong Ki Lee
Publikováno v:
Gastroenterology Research and Practice, Vol 2015 (2015)
Implantation of self-expanding metal stents (SEMS) is palliation for patients suffering from inoperable malignant obstructions associated with biliary and pancreatic cancers. Chemotherapeutic agent-eluting stents have been developed because SEMS are
Externí odkaz:
https://doaj.org/article/46a906c6a7c54aefa033b921e8bf8d6e
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49906 (2012)
Imbalance of lipid metabolism has been linked with pathogenesis of a variety of human pathological conditions such as diabetes, obesity, cancer and neurodegeneration. Sterol regulatory element binding proteins (SREBPs) are the master transcription fa
Externí odkaz:
https://doaj.org/article/8938a0a5eb9f4b74a4276db03c1f6f03
Publikováno v:
Neuroscience Letters. 767:136298
Alzheimer's disease (AD) is characterized by amyloid beta (Aβ) plaques and neurofibrillary tangles. AD drug development has been limited due to the presence of the blood–brain barrier (BBB), which prevents efficient uptake of therapeutics into the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44fcdc002fc134a964a88d495719367d
https://doi.org/10.1016/j.neulet.2021.136298
https://doi.org/10.1016/j.neulet.2021.136298
Publikováno v:
Molecular Endocrinology. 28:1186-1193
Metformin is a biguanide drug that is widely prescribed for type 2 diabetes. Metformin suppresses hepatic gluconeogenesis and increases fatty acid oxidation. Although studies have suggested that metformin acts, at least in part, via activation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c997bdca0b4970d4748bd7eb45a5443
https://doi.org/10.1210/me.2014-1134
https://doi.org/10.1210/me.2014-1134
Autor:
Kenneth S. Shindler, Sookhee Bang, Jaime H. Cheah, Joshua L. Dunaief, Ying Song, Sangwon F. Kim, Catherine Steenstra, Alyssa Cwanger, Yong Chen, Reas S. Khan, Solomon H. Snyder
Publikováno v:
The Journal of Neuroscience. 33:3582-3587
Dexras1, a small G-protein localized predominantly to the brain, is transcriptionally upregulated by the synthetic glucocorticoid dexamethasone. It has close homology to the Ras subfamily but differs in that Dexras1 contains an extended 7 kDa C-termi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d7bdef5d6bd9330fab57e95e5de45f3
https://doi.org/10.1523/jneurosci.1497-12.2013
https://doi.org/10.1523/jneurosci.1497-12.2013
Publikováno v:
Neuroscience Letters. 521:142-147
The Rhes/RASD2 GTPase complex is involved in dopamine D1/D2 receptor-mediated signaling and behavior. This GTP binding protein belongs to the RAS superfamily, along with Dexras1/RASD1, and is primarily expressed in the striatum. RASDs differ from typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef606ab4eca9ce511d5ebb51763c4bde
https://doi.org/10.1016/j.neulet.2012.05.073
https://doi.org/10.1016/j.neulet.2012.05.073
Autor:
Megan J. Dailey, Solomon H. Snyder, Sookhee Bang, Timothy H. Moran, Yong Chen, Seyun Kim, Sangwon F. Kim
Publikováno v:
Proceedings of the National Academy of Sciences. 109:616-620
The AMP-activated kinase (AMPK) senses the energy status of cells and regulates fuel availability, whereas hypothalamic AMPK regulates food intake. We report that inositol polyphosphate multikinase (IPMK) regulates glucose signaling to AMPK in a path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac354cfcc0d2643ee30aab06e423401
https://doi.org/10.1073/pnas.1119751109
https://doi.org/10.1073/pnas.1119751109
Autor:
Greg N. Carlson, Mary F. McMullen, Sookhee Bang, Hala Kazi, Mei Xuan Ho, Konrad Talbot, Yong Chen, Sangwon F. Kim, Steven E. Arnold, Wei-Yi Ong
Publikováno v:
Molecular neurobiology. 54(3)
Schizophrenia is a chronic deliberating neuropsychiatric disorder that affects about 1% of the population. Dystrobrevin-binding protein 1 (DTNBP1 or dysbindin) is one of Research Domain Constructs (RDoC) associated with cognition and is significantly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a651699db3e26388668bf94a8751c9
https://pubmed.ncbi.nlm.nih.gov/26873854
https://pubmed.ncbi.nlm.nih.gov/26873854