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Spotlight on Pimavanserin Tartrate and Its Therapeutic Potential in the Treatment of Major Depressive Disorder: The Evidence to Date

Autor: Vicki Soogrim, James M. Murrough, Manish K. Jha, Valerie L. Ruberto

Publikováno v: Drug Design, Development and Therapy

Major depressive disorder (MDD) is widely prevalent and one of the leading causes of disability. Treatment outcomes remain suboptimal with 1 in 3 patients with MDD responding inadequately to commonly used antidepressants. Pimavanserin, an atypical an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aafb308f44d7d74fdc731e2e0d8a8d87
http://europepmc.org/articles/PMC7812044

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Spotlight on Pimavanserin Tartrate and Its Therapeutic Potential in the Treatment of Major Depressive Disorder: The Evidence to Date

Autor: Soogrim,Vicki, Ruberto,Valerie L, Murrough,James, Jha,Manish Kumar

Publikováno v: Drug Design, Development and Therapy.

Vicki Soogrim,1,* Valerie L Ruberto,1,* James Murrough,1,2 Manish Kumar Jha1,2 1Depression and Anxiety Center for Discovery and Treatment, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA; 2Department of Neuroscien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dovemedicalp::45417dd03633cbdc5ef9bb0697e0f428
https://www.dovepress.com/spotlight-on-pimavanserin-tartrate-and-its-therapeutic-potential-in-th-peer-reviewed-article-DDDT

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Genetic variation in IRF4 expression modulates growth characteristics, tyrosinase expression and interferon-gamma response in melanocytic cells

Autor: Reuben S.Q. Kim, Stephen A. Ainger, Hilary X.L. Yong, Aaron G. Smith, Wen Lim, Melinda M. Ashcroft, Richard A. Sturm, Arish Soogrim, Dayana Nur Mahiuddin, Mitchell Fane, Graeme J. Walker, Scott A. Beatson, Darren J. Smit, Yash Chhabra, K. Jagirdar

Publikováno v: Pigment cellmelanoma research. 31(1)

A SNP within intron4 of the interferon regulatory factor4 (IRF4) gene, rs12203592*C/T, has been independently associated with pigmentation and age-specific effects on naevus count in European-derived populations. We have characterized the cis-regulat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9165186052e4c87b7739e478f9020803
https://pubmed.ncbi.nlm.nih.gov/28755520

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Interdisciplinary communication in the intensive care unit at the University Hospital of the West Indies

Autor: L P T, Chang, H E, Harding, I, Tennant, D, Soogrim, K, Ehikhametalor, B, James, A, Frankson, G M, Gordon-Strachan

Publikováno v: The West Indian medical journal. 59(6)

To assess the perceptions of physicians and nurses working full-time in the Intensive Care Unit (ICU) at the University Hospital of the West Indies (UHWI) regarding interdisciplinary communication.A cross-sectional survey of all medical personnel wor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0fb3a5d3f6aaa1078bea3a3569df2163
https://pubmed.ncbi.nlm.nih.gov/21702238

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Dynamics of antibiotic usage in the intensive care unit at the University Hospital of the West Indies

Autor: V, Chin, H E, Harding, I, Tennant, D, Soogrim, G M, Gordon-Strachan, M A, Frankson

Publikováno v: The West Indian medical journal. 59(2)

To determine antibiotic usage patterns in the Intensive Care Unit (ICU) at the University Hospital of the West Indies (UHWI).A cross-sectional, analytical study of consecutive patients admitted to the ICU was conducted between July and December 2007.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0cd075be5ff08abffb775352dbacc292
https://pubmed.ncbi.nlm.nih.gov/21275119

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Utilization pattern and cost of sedation, analgesia and neuromuscular blockade in a multidisciplinary intensive care unit

Autor: S, Hariharan, G, Pillai, D, Chen, S, Soogrim, J, Nelson, R, Tsoi-a-Fatt, K, Mohan, V, Boodhai

Publikováno v: The West Indian medical journal. 57(2)

To study the utilization pattern and the cost of sedatives, analgesics and neuromuscular blocking agents in a multidisciplinary intensive care unit (ICU).A prospective observational study was conducted in the ICU of the Eric Williams Medical Sciences

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8ef1c059ca558ad3128de168dc5a56e2
https://pubmed.ncbi.nlm.nih.gov/19565952

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A national survey on preoperative fasting policies and practices in Jamaican hospitals

Autor: C D, McGaw, E, Ehikhametalor, M, Nelson, D, Soogrim

Publikováno v: The West Indian medical journal. 53(4)

Controversy has arisen regarding the length and nature of the preoperative fast that should be required of patients with normal gastric emptying time undergoing elective surgery. Various studies and editorials have indicated that the traditional preo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3f66fa77aff1f16d50a2c6a97486437e
https://pubmed.ncbi.nlm.nih.gov/15622672

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Akademický článek

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Akademický článek

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