Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Soochan Bae"'
Autor:
Soochan Bae, Minhyung Park, Changsun Kang, Serkan Dilmen, Tae Hi Kang, Dong Goo Kang, Qingen Ke, Seung Uk Lee, Dongwon Lee, Peter M. Kang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 11 (2016)
BackgroundDuring myocardial ischemia/reperfusion (I/R), a large amount of reactive oxygen species (ROS) is produced. In particular, overproduction of hydrogen peroxide (H2O2) is considered to be a main cause of I/R‐mediated tissue damage. We genera
Externí odkaz:
https://doaj.org/article/b0fcf4b017964582b85516344764ba7e
Publikováno v:
Medicines, Vol 5, Iss 2, p 38 (2018)
Cardiovascular diseases (CVDs) have become prominent in mortality and morbidity rates. Prevalent cardiovascular conditions, such as hypertension, atherosclerosis and oxidative stress, are increasing at an alarming rate. Conventional drugs have been a
Externí odkaz:
https://doaj.org/article/884dcba392e146fa95aa8671a790d6b0
Autor:
Sangita Choudhury, Soochan Bae, Qingen Ke, Ji Yoo Lee, Sylvia S Singh, René St-Arnaud, Federica Del Monte, Peter M Kang
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108382 (2014)
Altered vitamin D signaling is associated with cardiac dysfunction, but the pathogenic mechanism is not clearly understood. We examine the mechanism and the role of vitamin D signaling in the development of cardiac dysfunction.We analyzed 1α-hydroxy
Externí odkaz:
https://doaj.org/article/e90a0937a07c4b739d5262cd118d98df
Autor:
Shi Su, Peter M. Kang, Ruijian Li, Dongwon Lee, Qingen Ke, Ye Eun Koo, Changsun Kang, Chul-Gyu Song, Chloe Ryu, Soochan Bae, Sang Jae Rhee
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics. 26:279-288
Mortality and morbidity after cardiac arrest remain high due to ischemia/reperfusion (I/R) injury causing multi-organ damages, even after successful return of spontaneous circulation. We previously generated H2O2-activatable antioxidant nanoparticles
Autor:
Brandy Houser, Ian Morrison, Peter M. Kang, Jake Reder, Edward Van Keuren, Koichiro Minami, Abdala Elkhal, Hirofumi Uehara, Jasper Iske, Michael W. Fanger, Astrid Wiens, Chen Zhao, Haruhito Azuma, Dongwon Lee, Stefan G. Tullius, Soochan Bae
Publikováno v:
Am J Transplant
Inflammatory responses associated with ischemia/reperfusion injury (IRI) play a central role in alloimmunity and transplant outcomes. A key event driving these inflammatory responses is the burst of reactive oxygen species, with hydrogen peroxide (H(
Autor:
Ruijian Li, Wen Ai, Soochan Bae, Eesac Lee, Qingen Ke, Dohyun Yoo, Shi Su, Peter M. Kang, Sangyong Jon, Yanwei Chen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Ischemia/reperfusion (I/R) injury causes overproduction of reactive oxygen species, which are the major culprits of oxidative stress that leads to inflammation, apoptosis, myocardial damage, and dysfunction. Bilirubin acts as a potent endo
Autor:
Eitezaz, Mahmood, Soochan, Bae, Omar, Chaudhary, Ruby, Feng, Feroze, Mahmood, Simon, Robson, Dongwon, Lee, Peter M, Kang, Robina, Matyal
Publikováno v:
European journal of pharmacology. 882
Neuropeptide-Y (NPY) leads to angiogenesis and remodeling of the ischemic myocardium. The objective of this study is to assess the therapeutic potential of NPY in a model of acute myocardial ischemia using a nanoparticles delivery system targeted to
Autor:
Sun Youn Bae, Chaehong Lim, Won Bo Lee, Ji Ho Ryu, Dongjun Jung, Soochan Bae, Dae-Hyeong Kim, Peter M. Kang, Ji Woong Yu, Sang Ihn Han, Min-Cheol Lee, Hye Jin Hwang, Suji Choi, Taeghwan Hyeon, Kyungpyo Park, Ok Kyu Park, Cory M. Tschabrunn, Sang Woo Lee, Reza Nezafat
Publikováno v:
Nature Nanotechnology. 13:1048-1056
Wearable and implantable devices require conductive, stretchable and biocompatible materials. However, obtaining composites that simultaneously fulfil these requirements is challenging due to a trade-off between conductivity and stretchability. Here,
Publikováno v:
Advanced Therapeutics. 4:2000273
Autor:
Derek Eshun, Qingen Ke, Robina Matyal, Soochan Bae, Rabya Saraf, Dongwon Lee, Feroze Mahmood, Peter M. Kang, Jelliffe Jeganathan, Serkan Dilmen
Publikováno v:
Journal of Applied Physiology. 122:1388-1397
We generated a novel nanoparticle called PVAX, which has intrinsic antiapoptotic and anti-inflammatory properties. This nanoparticle was loaded with neuropeptide Y3–36 (NPY3–36), an angiogenic neurohormone that plays a central role in angiogenesi