Zobrazeno 1 - 10
of 139
pro vyhledávání: '"SooYeun Lee"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Persistent neurochemical and biological disturbances resulting from repeated cycles of drug reward, withdrawal, and relapse contribute to drug dependence. Methamphetamine (MA) is a psychostimulant with substantial abuse potential and neuroto
Externí odkaz:
https://doaj.org/article/5820fdd670f245e6a1fdeb1332838782
Autor:
Khang-Yen Pham, Shristi Khanal, Ganesh Bohara, Nikesh Rimal, Sang-Hoon Song, Thoa Thi Kim Nguyen, In-Sun Hong, Jinkyung Cho, Jong-Sun Kang, Sooyeun Lee, Dong-Young Choi, Simmyung Yook
Publikováno v:
Redox Biology, Vol 79, Iss , Pp 103457- (2025)
The dynamic equilibrium between acetylation and deacetylation is vital for cellular homeostasis. Parkinson's disease (PD), a neurodegenerative disorder marked by α-synuclein (α-syn) accumulation and dopaminergic neuron loss in the substantia nigra,
Externí odkaz:
https://doaj.org/article/31b1be9379a74c7c8c5a1efd31c40186
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 568 (2024)
Age-related macular degeneration (AMD) severely affects central vision due to progressive macular degeneration and its staggering prevalence is rising globally, especially in the elderly population above 55 years. Increased oxidative stress with agin
Externí odkaz:
https://doaj.org/article/b84572099b6049778f2978df499e67cc
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2024)
IntroductionMethamphetamine use disorder (MUD) is a chronic relapsing disorder characterized by compulsive Methamphetamine (MA) use despite its detrimental effects on physical, psychological, and social well-being. The development of MUD is a complex
Externí odkaz:
https://doaj.org/article/501fc284e81c4d74b3ee5377afd8dd40
Autor:
Sang-Hoon Song, Won-Jun Jang, Eun Young Jang, Oc-Hee Kim, Haesoo Kim, Taekwon Son, Dong-Young Choi, Sooyeun Lee, Chul-Ho Jeong
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
MicroRNA (miRNA)-mediated striatal gene regulation may play an important role in methamphetamine (METH) addiction. This study aimed to identify changes in novel miRNAs and their target genes during METH self-administration and investigate their roles
Externí odkaz:
https://doaj.org/article/5faed25a30e445d4b2714d7a4d4544c5
Autor:
Suji Kim, Suein Choi, Min Seo Lee, Mingyu Kim, Maria Park, Sungpil Han, Seunghoon Han, Hye Suk Lee, Sooyeun Lee
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Gamma-hydroxybutyric acid (GHB), used as a therapeutic and an illegal anesthetic, is a human neurotransmitter produced during gamma-aminobutyric acid (GABA) biosynthesis and metabolism. Potential biomarker metabolites of GHB intoxication have been id
Externí odkaz:
https://doaj.org/article/7b3c83fd0ad8462fbf7900a818817d35
Publikováno v:
Metabolites, Vol 13, Iss 2, p 180 (2023)
Gamma-hydroxybutyric acid (GHB) is a potent, short-acting central nervous system depressant as well as an inhibitory neurotransmitter or neuromodulator derived from gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter. The sodium salt
Externí odkaz:
https://doaj.org/article/a2e29816fe2245a0890466b5a196a5cd
Autor:
Kwang-Hyun Hur, YouYoung Lee, Audrey Lynn Donio, Shi-Xun Ma, Bo-Ram Lee, Seon-Kyung Kim, Jae-Gyeong Lee, Young-Jung Kim, MinJeong Kim, SeolMin Yoon, SooYeun Lee, Yong-Sup Lee, Seok-Yong Lee, Choon-Gon Jang
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 710 (2022)
Mepirapim is a synthetic cannabinoid that has recently been abused for recreational purposes. Although serious side effects have been reported from users, the dangerous pharmacological effects of Mepirapim have not been scientifically demonstrated. I
Externí odkaz:
https://doaj.org/article/bc50556167c644cba4219c6b3ab03d0a
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Cudratrixanthone U (CTU) is a prenylated xanthone compound isolated from Maclura tricuspidata Bureau (Moraceae). Prenylated xanthones have been reported to exhibit a variety of biological activities. However, the effects of prenylated xanthone on ost
Externí odkaz:
https://doaj.org/article/593eba8c0e784ab7b000ab96d20ae73d
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 7, Pp 1-13 (2018)
Protein modification: Effect on activity Enzymes that modify proteins by adding an acetyl group have profound effects on metabolism and development, as well as disease. This process, known as acetylation, is carried out by KAT proteins, which are pre
Externí odkaz:
https://doaj.org/article/b02f128f87d345e89b285e4d1736c06d