Zobrazeno 1 - 10
of 271
pro vyhledávání: '"Soo Woong, Kim"'
Publikováno v:
The World Journal of Men's Health, Vol 39, Iss 3, Pp 541-549 (2021)
Purpose: To determine if chronic administration of Jun-amino terminal kinase (JNK)-inhibitors and LIM-kinase 2 (LIMK2)-inhibitors from the immediate post-injury period in a rat model of cavernous-nerve-crush-injury could normalize cavernous-veno-occl
Externí odkaz:
https://doaj.org/article/c8b0012204a3466c821723f6edd3086d
Publikováno v:
The Journal of Sexual Medicine. 20:749-755
Background Structural alterations of the penis, including cavernosal apoptosis and fibrosis, induce venous leakage into the corpus cavernosum or cavernosal veno-occlusive dysfunction, a key pathophysiology associated with erectile dysfunction after r
Publikováno v:
The World Journal of Men's Health, Vol 37, Iss 2, Pp 210-218 (2019)
Purpose: To compare the improving effects of diabetic erectile dysfunction with two anti-glycemic agents; phlorizin and insu-lin. Materials and Methods: Sixty Sprague-Dawley rats were divided into four groups (n=15 in each group): normal control (C)
Externí odkaz:
https://doaj.org/article/64cbd93a4e1e4546b3562d3b2caf36d0
Autor:
Min Chul Cho, Jung Kwon Kim, Sang Hoon Song, Sung Yong Cho, Sang Wook Lee, Soo Woong Kim, Jae-Seung Paick
Publikováno v:
Asian Journal of Andrology, Vol 20, Iss 1, Pp 69-74 (2018)
This study aimed to investigate perceived ejaculatory function/satisfaction before treatment for lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH) and to identify associations between specific categories of ejaculatory dysfunctio
Externí odkaz:
https://doaj.org/article/ea07994d1c9b404cb3052fd9aa285ba6
Publikováno v:
Asian Journal of Andrology, Vol 20, Iss 1, Pp 50-55 (2018)
The present study aimed to identify which mitogen-activated protein kinase (p38 or Jun amino-terminal kinase [JNK]) was involved in cavernosal apoptosis during the acute phase after cavernosal nerve crush injury (CNCI) in rats to ameliorate apoptosis
Externí odkaz:
https://doaj.org/article/66249ca277244336a0cd54f40bcb0961
Autor:
Juhyun Park, Sung Yong Cho, Kwanjin Park, Ji Sun Chai, Hwancheol Son, Soo Woong Kim, Jae-Seung Paick, Min Chul Cho
Publikováno v:
Asian Journal of Andrology, Vol 20, Iss 4, Pp 372-378 (2018)
We evaluated whether LIM-kinase 2 inhibitor (LIMK2i) could improve erectile function by suppressing corporal fibrosis through the normalization of the Rho-associated coiled-coil protein kinase 1 (ROCK1)/LIMK2/Cofilin pathway in a rat model of caverno
Externí odkaz:
https://doaj.org/article/bca059e41a5c4baa8594c839a1dc5847
Publikováno v:
Cells, Vol 11, Iss 1, p 78 (2021)
The LIM kinases (LIMK1 and LIMK2), known as downstream effectors, and the Rho-associated protein kinase (ROCK), a regulator of actin dynamics, have effects on a diverse set of cellular functions. The LIM kinases are involved in the function of the ma
Externí odkaz:
https://doaj.org/article/82d9b71f3d694d259eb964b3a4782b34
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 12698 (2021)
We determined if combined administration of JNK-inhibitors and HGF (hepatocyte-growth-factor) would restore erectile-function through both antiapoptotic and regenerative effects in a rat model of cavernous-nerve-crush-injury (CNCI), and compared the
Externí odkaz:
https://doaj.org/article/f3e2d925b9d44a369a3ed8b450ee8e40
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213586 (2019)
We evaluated whether chronic administration of LIMK2-inhibitors could improve erectile function by alleviating CVOD through suppressing cavernosal fibrosis in a rat model of cavernosal nerve crush-injury (CNCI). Forty-two 12-week-old rats were equall
Externí odkaz:
https://doaj.org/article/f9dd8e05516a4c128218bddf9c3aecaf
Publikováno v:
Andrology. 10:758-766
The main pathophysiologic conditions of erectile dysfunction (ED) after radical prostatectomy are considered to be corporal fibrosis and apoptosis induced by cavernosal nerve (CN) injury.In a rat model of CN crush injury (CNCI), we investigated wheth