Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Soo Peang Khor"'
Autor:
Soo-Peang Khor, Ann Hsu
Publikováno v:
Current Clinical Pharmacology. 2:234-243
Levodopa, a prodrug of dopamine, remains to be one of the main drugs in the treatment of Parkinson's disease. All current levodopa products are formulated with aromatic amino acid decarboxylase inhibitors such as carbidopa or benserazide to prevent t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9659b2bb7887ed7c5a7b8af2dd5f6711
https://doi.org/10.2174/157488407781668802
https://doi.org/10.2174/157488407781668802
Autor:
Leo M. Albert, Chih-Ming Leo Tseng, Andrew J. Dorner, Page Bouchard, Ron L. Peterson, James C. Keith, Soo-Peang Khor
Publikováno v:
Pharmaceutical Research. 17:482-485
Recently, rhIL-11 was developed as an enteric-coated In Vivo Absorption Properties of multiparticulate formulation for oral dosing of patients with Orally Administered Recombinant inflammatory bowel disease. Therefore, we conducted a series of PK stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7771ad91a40545009523588ef2a4c03d
https://doi.org/10.1023/a:1007545524408
https://doi.org/10.1023/a:1007545524408
Publikováno v:
Pharmaceutical Research. 15:1643-1646
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3262b9b76612ba645725f71ef72152b3
https://doi.org/10.1023/a:1011979822478
https://doi.org/10.1023/a:1011979822478
Autor:
Eric K. Rowinsky, Marna Doucette, Ross C. Donehower, Sharyn D. Baker, Louise B. Grochow, Alex A. Adjei, Tom Spector, Dennis A. Noe, John A. Hohneker, Soo Peang Khor, S E Sartorius
Publikováno v:
Journal of Clinical Oncology. 14:3085-3096
PURPOSE To study the absolute bioavailability and pharmacokinetics of an oral solution of fluorouracil (5-FU) in patients treated with 776C85, an oral inactivator of dihydropyrimidine dehydrogenase (DPD), and to evaluate the feasibility of administer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88f1202712115b0093ceccf9d8dffa17
https://doi.org/10.1200/jco.1996.14.12.3085
https://doi.org/10.1200/jco.1996.14.12.3085
Autor:
Natarajan Raghunand, David Brown Wilson, Soo-Peang Khor, Olivia Longacre, Jason D. Lickliter, Howard P. Hendrickson, Evan C. Unger
Publikováno v:
Journal of Clinical Oncology. 33:TPS2078-TPS2078
TPS2078 Background: Post-resected glioblastoma multiforme (GMB) patients were treated with dodecafluoropentane emulsion (DDFPe) to evaluate the pharmacokinetics (PK), safety and potential survival ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::103a28f85c38f44073e0af1301a016de
https://doi.org/10.1200/jco.2015.33.15_suppl.tps2078
https://doi.org/10.1200/jco.2015.33.15_suppl.tps2078
Autor:
Marina W.H. Shen, Mario D. Gonzalez, John C. McKew, Wen Zhang, Tam Steve Yik-Kai, Howard Sard, Kun Wu, Soo Peang Khor, Paresh Thakker, Mark L. Behnke, Shanghao Liu, Megan A. Foley, Frank Lovering, Fuk-Wah Sum, Anu Mahadevan, James D. Clark
Publikováno v:
Journal of medicinal chemistry. 49(1)
Compound 1 was previously reported to be a potent inhibitor of cPLA(2)alpha in both artificial monomeric substrate and cell-based assays. However, 1 was inactive in whole blood assays previously used to characterize cyclooxygenase and lipoxygenase in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97c459eda2a1b8504a723428c64b087
https://pubmed.ncbi.nlm.nih.gov/16392799
https://pubmed.ncbi.nlm.nih.gov/16392799
Publikováno v:
Journal of pharmacological and toxicological methods. 47(1)
Introduction: The purpose of this study was to evaluate the feasibility of using gel electrophoresis combined with autoradiographic image analysis for quantitating protein drug concentrations in biological fluid for pharmacokinetic studies. Methods:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf323407a4b125ccdf4403111cf0a4d
https://pubmed.ncbi.nlm.nih.gov/12387940
https://pubmed.ncbi.nlm.nih.gov/12387940
Autor:
Go Ning, Denise Nazzal, Lyssa Villarreal, Preeti Pattamata, Soo-Peang Khor, Karen Delavan-Boorsma, Tong Lin, Robert J. Tressler
Publikováno v:
Cancer Research. 70:3202-3202
Telomerase activation is a hallmark of cancer and is critical for dysregulated cell proliferation and cell immortality. Increased telomerase activities were detected in essentially all epithelium derived cancers tested up-to-date and in many hematolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::993d89236e1e107e3eaf05c74393123b
https://doi.org/10.1158/1538-7445.am10-3202
https://doi.org/10.1158/1538-7445.am10-3202
Publikováno v:
Journal of pharmaceutical sciences. 80(11)
We evaluate here an area term, the area under the rate of change of concentration-time curve (AURC), which allows the determination of the initial or central volume of distribution (V 1 ). It has previously been shown that AURC is equal to the sum of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a054c895d43afea3e0b544c48628613
https://pubmed.ncbi.nlm.nih.gov/1815055
https://pubmed.ncbi.nlm.nih.gov/1815055
Autor:
Jennifer A. Smith, Carol Ann Huff, Mohamad A. Hussein, Laurence Elias, Asher A. Chanan-Khan, Nikhil C. Munshi, Soo-Peang Khor, Benedetti Fabio
Publikováno v:
Blood. 112:3688-3688
Telomerase over-expression is the predominant mechanism by which cancer cells maintain adequate telomere length to achieve immortalization. Telomere length is often decreased and telomerase activity is often increased in MM. GRN163L is a 13-mer oligo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebc97e643eabb4f71c8f8af2b7c4f48d
https://doi.org/10.1182/blood.v112.11.3688.3688
https://doi.org/10.1182/blood.v112.11.3688.3688