Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Soo Mun Ngoi"'
Publikováno v:
Toxins, Vol 2, Iss 7, Pp 1898-1912 (2010)
In response to environmental cues the human pathogen Staphylococcus aureus synthesizes and releases proteinaceous enterotoxins. These enterotoxins are natural etiologic entities of severe food poisoning, toxic shock syndrome, and acute diseases. Stap
Externí odkaz:
https://doaj.org/article/dffb9d14f6274db49e389bd563964991
Autor:
John T. Chang, Ichiro Taniuchi, Kiyokazu Kakugawa, Sonia Feau, Björn F. Lillemeier, Bjoern Peters, Ikuo Takazawa, Hitoshi Iwaya, Amnon Altman, Laetitia Seguin, Ildefonso Vicente-Suarez, Hilde Cheroutre, Pandurangan Vijayanand, Nicolas Thiault, Benjamin J Schmiedel, Soo-Mun Ngoi, Jr-Wen Shui, Stéphane Bécart, Christopher J. Lena, Mitchell Kronenberg, Alexandre Larange, Yujun Huang
Publikováno v:
SSRN Electronic Journal.
Ligation of nuclear retinoic acid receptors (RARs) by retinoic acid (RA) activates transcription and promotes cell differentiation. RARs can also participate in non-genomic functions in extra-nuclear spaces. Here we identify an alternative isoform of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4929541d753e45e19441349e7409058f
https://doi.org/10.2139/ssrn.3335780
https://doi.org/10.2139/ssrn.3335780
Autor:
Stephen P. Mayfield, John T. Chang, Charles B. Shoemaker, Michelle Debatis, Yung-Nien Chang, Julian N. Rosenberg, George A. Oyler, Daniel J. Barrera, Soo-Mun Ngoi, Joanna G. Chiu
Publikováno v:
Plant Biotechnology Journal. 13:117-124
Summary We have produced three antitoxins consisting of the variable domains of camelid heavy chainonly antibodies (V H H) by expressing the genes in the chloroplast of green algae. These antitoxins accumulate as soluble proteins capable of binding a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e63cc97aea7f9df8a3ee81ec8eb07220
https://doi.org/10.1111/pbi.12244
https://doi.org/10.1111/pbi.12244
Publikováno v:
Journal of Leukocyte Biology. 88:21-31
The data provide impetus for using TLR-based peripheral vaccination to augment specific Th17 immunity in the gut mucosa. Lipopolysaccharide (LPS) is a potent natural adjuvant, commonly used to amplify Th1 responses. Here, we report that systemic immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2070744e01fef254b84089df1ca33377
https://doi.org/10.1189/jlb.0909631
https://doi.org/10.1189/jlb.0909631
Autor:
Antoine Ménoret, David L. Allen, Nicholas A. Eddy, Seung-Joo Lee, Soo-Mun Ngoi, Nitya G. Chakraborty, Gabriel Fenteany, Bijay Mukherji, Robert J. Rossi, Swagatam Ray, Anthony T. Vella, Jeremy P. McAleer
Publikováno v:
The Journal of Immunology. 183:7489-7496
Damaging inflammation arising from autoimmune pathology and septic responses results in severe cases of disease. In both instances, anti-inflammatory compounds are used to limit the excessive or deregulated cytokine responses. We used a model of robu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56c70355a53b38f49e9570553383387e
https://doi.org/10.4049/jimmunol.0901414
https://doi.org/10.4049/jimmunol.0901414
Publikováno v:
Molecular Pharmacology. 70:267-276
The MDR1 multidrug transporter represents one of the better characterized drug transporters that play an important role in protecting the body against xenobiotic insults. Single nucleotide polymorphisms (SNPs) and SNP haplotypes within this gene have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0deafb000bc42dcdd0133242ab05489
https://doi.org/10.1124/mol.105.019810
https://doi.org/10.1124/mol.105.019810
Autor:
Dirk E. Smith, Anthony T. Vella, Antoine Ménoret, Soo Mun Ngoi, Adam J. Adler, Marie-Clare St. Rose, Michael G. Tovey
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(26)
The synthetic double-stranded RNA poly(I:C) is commonly used as an adjuvant to boost CD8 T-cell function; however, polyinosinic:polycytidylic acid [poly(I:C)] can also suppress autoimmune disease. The mechanism by which a single adjuvant achieves two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::821a149cf06c428cf839317268933519
https://pubmed.ncbi.nlm.nih.gov/22689946
https://pubmed.ncbi.nlm.nih.gov/22689946
Publikováno v:
Discovery medicine. 12(66)
Over the past three decades the incidence of allergic disorders and autoimmune diseases has risen and this trend is particularly prominent in developed nations. The hygiene hypothesis suggests that as a living environment becomes more sanitized, chil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::80b869bb338ec436f36b1f97f6c33033
https://pubmed.ncbi.nlm.nih.gov/22127111
https://pubmed.ncbi.nlm.nih.gov/22127111
Poly(I:C) is an adjuvant used for antitumor treatment and vaccines because of its prominent effects on CD8 T cells and NK cells. Poly(I:C) binds TLR3 and this interaction is thought to be central for driving cell-mediated immune responses. We investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2861ec29f5dabbdbb120547bc62359b
https://europepmc.org/articles/PMC2676428/
https://europepmc.org/articles/PMC2676428/
Publikováno v:
Current gene therapy. 4(1)
Efficient and regulated co-expression of multiple genes is an important consideration in the design of gene therapy vectors. While the augmentation of a single therapeutic gene is often sufficient for gene therapy of simple mendelian disorders, strat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531ad20bb7f84c35c1b912c19afeeb0d
https://pubmed.ncbi.nlm.nih.gov/15032611
https://pubmed.ncbi.nlm.nih.gov/15032611