Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Soo K. Bae"'
Autor:
Wan Gyoon Shin, Jee Hyun Suh, Hee Eun Kang, Myung Gull Lee, Hye Duck Choi, Jeong Yoon Lee, Soo K. Bae
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 51:718-724
Hydrochlorothiazide (HCTZ) is used to treat uncomplicated hypertension. However, many studies have reported the variance of inter-individual response to HCTZ. A meta-analysis of published data was conducted to evaluate the pharmacogenetic association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6e59651442bd426051b0f988e13933
https://doi.org/10.5414/cp201899
https://doi.org/10.5414/cp201899
Autor:
Jae-Gook Shin, Soo K. Bae, Su-Jun Lee, Ji-Hong Shon, Byoung Doo Rhee, Chang-Woo Yeo, Eun Young Kim, Sang Seop Lee
Publikováno v:
Drug Metabolism and Disposition. 39:711-716
The objectives of this study were to identify the genetic variants of CYP2C8, analyze CYP2C8 single nucleotide polymorphisms (SNPs), and characterize their functional consequences in the CYP2C8 substrate drug rosiglitazone in humans. The direct full
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd0e1dd1fe20f9fdab7eac9a68772eee
https://doi.org/10.1124/dmd.110.035899
https://doi.org/10.1124/dmd.110.035899
Publikováno v:
Journal of Pharmacy and Pharmacology. 61:1637-1642
Objectives It has been reported that hepatic cytochrome P450 (CYP)2C9 and CYP3A4 are responsible for the metabolism of sildenafil and formation of its metabolite, N-desmethylsildenafil, in humans. However, in-vivo studies in rats have not been report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::486d024f7ea40a35326011fb9fca65cc
https://doi.org/10.1211/jpp.61.12.0008
https://doi.org/10.1211/jpp.61.12.0008
Publikováno v:
Biopharmaceutics & Drug Disposition. 28:87-95
It has been reported that plasma albumin concentrations were significantly lower in cancer patients than those in the healthy volunteers, and the expression and mRNA level of hepatic microsomal cytochrome P450 (CYP) 1A2 increased in mutant Nagase ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59fc0258d914dec6b02723f886f6b2d9
https://doi.org/10.1002/bdd.534
https://doi.org/10.1002/bdd.534
Publikováno v:
Biopharmaceutics & Drug Disposition. 28:385-392
It has been reported that the plasma (or serum) levels of albumin and globulins were lower and higher, respectively, than the serum levels in control rats. Hence, it could be expected that these changes could affect the renal clearance (Cl(r)) of met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa9968afa87e102630fc237e704df90d
https://doi.org/10.1002/bdd.565
https://doi.org/10.1002/bdd.565
Publikováno v:
Biopharmaceutics & Drug Disposition. 28:445-454
It has been reported that the expressions of hepatic microsomal cytochrome P450 (CYP) 1A1/2, 2B1/2 and 3A1/2 were not changed in rats with water deprivation for 72 h (rat model of dehydration) compared with the controls. It has been also reported tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5003badab82eba582e5893e77ebc3cff
https://doi.org/10.1002/bdd.573
https://doi.org/10.1002/bdd.573
Publikováno v:
Journal of Pharmaceutical Sciences. 95:998-1005
Pharmacokinetic parameters of oltipraz were compared after intravenous (10 mg/kg) and oral (50 mg/kg) administration to control male Sprague–Dawely rats and mutant Nagase analbuminemic rats (NARs). In NARs, the expression and mRNA level of CYP1A2 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755ec4dcdb252de15b06003954151326
https://doi.org/10.1002/jps.20602
https://doi.org/10.1002/jps.20602
Pharmacokinetics of oltipraz in rat models of diabetes mellitus induced by alloxan or streptozotocin
Publikováno v:
Life Sciences. 78:2287-2294
Pharmacokinetic parameters of oltipraz were compared after intravenous (10 mg/kg) and oral (30 mg/kg) administration in rat model of diabetes mellitus induced by alloxan (rat model of DMIA) or streptozotocin (rat model of DMIS) and their respective c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac280af6543913094303e909b1c53df
https://doi.org/10.1016/j.lfs.2005.09.031
https://doi.org/10.1016/j.lfs.2005.09.031
Publikováno v:
Biopharmaceutics & Drug Disposition. 27:147-156
The pharmacokinetic parameters of DA-7867 were compared after intravenous and oral administration at a dose of 10 mg/kg in control rats and in rats with water deprivation for 72 h (rat model of dehydration). After intravenous administration in the ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa82f9ab628ca381e07ad7a7afc9fab
https://doi.org/10.1002/bdd.496
https://doi.org/10.1002/bdd.496
Publikováno v:
Journal of Pharmacy and Pharmacology. 57:1397-1405
The pharmacokinetic interaction between 5-[2-propyloxy-5-(1-methyl-2-pyrollidinylethylamidosulfonyl)phenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo (4,3-d)pyrimidine-7-one (DA-8159), a new erectogenic, and nitroglycerin has been evaluated in rats.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004dfe9b10b192c17426f1ef24ec9a3f
https://doi.org/10.1211/jpp.57.11.0004
https://doi.org/10.1211/jpp.57.11.0004