Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Soo Hyeon Shin"'
Publikováno v:
Therapeutic Innovation & Regulatory Science. 54:693-700
For topically applied over-the-counter (OTC) products, the association of unwanted systemic exposure and adverse events may be difficult to ascertain without a recognition or determination of in vivo absorption. Evaluation of skin permeability using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50333289df2c9bf893922881885c7be
https://doi.org/10.1007/s43441-019-00104-3
https://doi.org/10.1007/s43441-019-00104-3
Autor:
Audra L. Stinchcomb, Mingming Yu, Sam G. Raney, Priyanka Ghosh, Soo Hyeon Shin, Hazem E. Hassan, Dana C. Hammell
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 342
The value of developing an in vitro/in vivo correlation (IVIVC) is substantial in biopharmaceutical drug development because once the model is developed and validated, an in vitro method may be used to efficiently assess and predict drug product perf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ffc2a9d6c22a17868baef74fc39efde
https://pubmed.ncbi.nlm.nih.gov/34838928
https://pubmed.ncbi.nlm.nih.gov/34838928
Autor:
Sam G. Raney, Priyanka Ghosh, Hazem E. Hassan, Elena Rantou, Soo Hyeon Shin, Audra L. Stinchcomb
Publikováno v:
Pharmaceutical Research. 37
The in vitro permeation test (IVPT) with a new statistical approach was investigated to evaluate the utility of an IVPT methodology as a sensitive tool to support a demonstration of bioequivalence (BE) for topical dermatological drug products. IVPT e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c8d2b42e389ec3d842dc93e98f50ac
https://doi.org/10.1007/s11095-020-02821-z
https://doi.org/10.1007/s11095-020-02821-z
Publikováno v:
Pharmaceutical Research. 37
Heat therapy is widely used for pain relief and may unintentionally be used in conjunction with pain relieving topical formulations. The purpose of this study was to evaluate the influence of heat on the permeation of diclofenac through porcine and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19388c7e25715d13d315d54a48426a7a
https://doi.org/10.1007/s11095-019-2741-1
https://doi.org/10.1007/s11095-019-2741-1
Autor:
Jukkarin Srivilai, Sarah Ibrahim, Hazem E. Hassan, Dana C. Hammell, Audra L. Stinchcomb, Soo Hyeon Shin, Caroline Strasinger
Publikováno v:
AAPS PharmSciTech. 19:2778-2786
Chemical penetration enhancers (CPEs) are frequently incorporated into transdermal delivery systems (TDSs) to improve drug delivery and to reduce the required drug load in formulations. However, the minimum detectable effect of formulation changes to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d26dab4ecaee9eedcf9d220c9dac5719
https://doi.org/10.1208/s12249-018-1130-0
https://doi.org/10.1208/s12249-018-1130-0
Autor:
Dana C. Hammell, Wilbur H. Chen, Melissa Billington, Sam G. Raney, Priyanka Ghosh, Sherin Thomas, Soo Hyeon Shin, Audra L. Stinchcomb, Hazem E. Hassan, Samer S. El-Kamary
Publikováno v:
Journal of Controlled Release. 270:76-88
The in vitro permeation test (IVPT) has been widely used to characterize the bioavailability (BA) of compounds applied on the skin. In this study, we performed IVPT studies using excised human skin (in vitro) and harmonized in vivo human serum pharma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f856b0b0cdad36ddd3e451274c5aebad
https://doi.org/10.1016/j.jconrel.2017.11.034
https://doi.org/10.1016/j.jconrel.2017.11.034
Autor:
Inas A. Abdallah, Audra L. Stinchcomb, Dana C. Hammell, Soo Hyeon Shin, Mingming Yu, Hazem E. Hassan
Publikováno v:
Bioanalysis. 9(20)
Aim: Fentanyl is an opioid agonist used for acute and chronic pain management. In this report, a highly sensitive and simple LC–MS/MS method using Hydrophilic Interaction Chromatography (HILIC) column was validated and used for fentanyl quantificat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9efeeeb73cab33be7915ab1b65bd3b3c
https://pubmed.ncbi.nlm.nih.gov/28914084
https://pubmed.ncbi.nlm.nih.gov/28914084
Autor:
Dana C. Hammell, Audra L. Stinchcomb, Hazem E. Hassan, Bryan Newman, Sam G. Raney, Priyanka Ghosh, Soo Hyeon Shin
Publikováno v:
Pharmaceutical research. 34(9)
At elevated temperatures, the rate of drug release and skin permeation from transdermal delivery systems (TDS) may be higher than at a normal skin temperature. The aim of this study was to compare the effect of heat on the transdermal delivery of two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a33e6d58718b0c1fa92873830cb383
https://pubmed.ncbi.nlm.nih.gov/28608140
https://pubmed.ncbi.nlm.nih.gov/28608140
Publikováno v:
Journal of pharmaceutical sciences. 100(4)
This study aimed to evaluate whether and how the internal structure and composition of liquid crystalline systems can be tailored to maximize paclitaxel cutaneous delivery. Liquid crystalline phases of water, Brij-97, and medium-chain mono/diglycerid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c69ba6caa8f58402bec9b3009750c3d
https://pubmed.ncbi.nlm.nih.gov/20957759
https://pubmed.ncbi.nlm.nih.gov/20957759