Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Soo Hyeon, Lee"'
Publikováno v:
Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-12 (2024)
Abstract Alcohol consumption, a pervasive societal issue, poses considerable health risks and socioeconomic consequences. Alcohol-induced hepatic disorders, such as fatty liver disease, alcoholic hepatitis, chronic hepatitis, liver fibrosis, and cirr
Externí odkaz:
https://doaj.org/article/2a782b1fd24c4b6095f2c1f60ff20bd6
Autor:
Yongjun Sunwoo, Sae Hyun Eom, Ji Seong Yun, Yujin Kim, Jeongmin Lee, Soo Hyeon Lee, Sooyoung Shin, Yeo Jin Choi
Publikováno v:
Medicina, Vol 60, Iss 7, p 1028 (2024)
Background and Objectives: Despite high incidences of cognitive impairment with aging, evidence on the prevalence and the seriousness of drug-induced cognitive impairment is limited. This study aims to evaluate the prevalence and the severity of drug
Externí odkaz:
https://doaj.org/article/35ce6241909a4713a465068fdc536537
Autor:
Kyung Hyeon Lee, Nadia Fazal Ali, Soo Hyeon Lee, Zhimin Zhang, Marie Burdick, Zachary J. Beaulac, Greg Petruncio, Linxia Li, Jiangdong Xiang, Ezra M. Chung, Kenneth W. Foreman, Schroeder M. Noble, Yun M. Shim, Mikell Paige
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The aminopeptidase activity (AP) of the leukotriene A4 hydrolase (LTA4H) enzyme has emerged as a therapeutic target to modulate host immunity. Initial reports focused on the benefits of augmenting the LTA4H AP activity and clearing its putat
Externí odkaz:
https://doaj.org/article/5e035599853c418c91141324ae6d3acc
Autor:
Hye-Jeong Kong, Dong-Hyun Kang, Tae-Sung Ahn, Kwang-Seock Kim, Tae-Wan Kim, Soo-Hyeon Lee, Dong-Woo Lee, Jae-Sung Ryu, Moo-Jun Beak
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16704 (2023)
Colorectal cancer (CRC) is one of the most common and deadly cancers in the world. However, no effective treatment for the disease has yet been found. For this reason, several studies are being carried out on the treatment of CRC. Currently, there is
Externí odkaz:
https://doaj.org/article/9d23cb0aad384c34959fa639d52ed781
Autor:
Yeon Hee Park, Samir Lal, Jeong Eon Lee, Yoon-La Choi, Ji Wen, Sripad Ram, Ying Ding, Soo-Hyeon Lee, Eric Powell, Se Kyung Lee, Jong Han Yu, Keith A. Ching, Jae-Yong Nam, Seok Won Kim, Seok Jin Nam, Ji-Yeon Kim, Soo Youn Cho, Seri Park, Jinho Kim, Soohyn Hwang, Yu Jin Kim, Vinicius Bonato, Diane Fernandez, Shibing Deng, Shuoguo Wang, Hyuntae Shin, Eun-Suk Kang, Woong-Yang Park, Paul A. Rejto, Jadwiga Bienkowska, Zhengyan Kan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Neoadjuvant chemotherapy is a therapeutic option for the treatment of breast cancer. Here, the authors characterize changes in the gene expression profiles and immune microenvironment in serial breast cancer biopsies taken before, during and after ne
Externí odkaz:
https://doaj.org/article/d34ef5fb3216481893b451cd685dff30
Autor:
Cheng-Hui Lin, Young Joo Sun, Soo Hyeon Lee, Elena M. Mujica, Caitlin R. Kunchur, Man-Ru Wu, Jing Yang, Youn Soo Jung, Bryce Chiang, Sui Wang, Vinit B. Mahajan
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101143- (2022)
Summary: Ocular drug implants (ODIs) are beneficial for treating ocular diseases. However, the lack of a robust injection approach for small-eyed model organisms has been a major technical limitation in developing ODIs. Here, we present a cost-effect
Externí odkaz:
https://doaj.org/article/c6541ccd293545ea8ee0602b6d77adb9
Autor:
Yoseop Kim, Soo-Hyeon Lee, Cheol-Jung Kim, Je-Jung Lee, Dohyeon Yu, Soomin Ahn, Dong-Jun Shin, Sang-Ki Kim
Publikováno v:
BMC Veterinary Research, Vol 15, Iss 1, Pp 1-11 (2019)
Abstract Background The antibody-dependent cellular cytotoxicity (ADCC) is a cell-mediated immune defense mechanism in which effector immune cells actively lyse antibody-coated target cells. The ADCC of tumor cells is employed in the treatment of var
Externí odkaz:
https://doaj.org/article/a391446f71a14eada791212e84fcf83f
Autor:
Hee Kyung Kim, Soo-Hyeon Lee, Yu Jin Kim, Song Ee Park, Han Sang Lee, Sung Won Lim, Jang Ho Cho, Ji-Yeon Kim, Jin Seok Ahn, Young-Hyuck Im, Jong Han Yu, Yeon Hee Park
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background In this study, we observe the patterns initial palliative treatment for premenopausal patients with HR-positive/HER2-negative MBC and determine if nonadherence to clinical guidelines are associated with worse clinical outcomes in
Externí odkaz:
https://doaj.org/article/d5b1472b3a79453bb818d90fbd70245a
Publikováno v:
World Journal of Gastrointestinal Surgery. 15:992-999
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a78a18774b3cacd73f382dc4703498d5
https://doi.org/10.4240/wjgs.v15.i5.992
https://doi.org/10.4240/wjgs.v15.i5.992
Autor:
Jennifer T. Vu, Elena Wang, Jolan Wu, Young Joo Sun, Gabriel Velez, Alexander G. Bassuk, Soo Hyeon Lee, Vinit B. Mahajan
Publikováno v:
Trends in Molecular Medicine. 28:644-661
Ophthalmic neurodegenerative diseases encompass a wide array of molecular pathologies unified by calpain dysregulation. Calpains are calcium-dependent proteases that perpetuate cellular death and inflammation when hyperactivated. Calpain inhibition t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f7a9c292bcb9484e484d9b1c019d4c
https://doi.org/10.1016/j.molmed.2022.05.007
https://doi.org/10.1016/j.molmed.2022.05.007