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Publikováno v:
Acta Reumatológica Portuguesa, Vol 2018, Iss 3, Pp 210-216 (2018)
Background: Digital ulcers (DUs) in Systemic sclerosis (SSc) result from recurrent Raynaud’s phenomenon (RP) and microtrauma with high impact on quality of life. Medical use of ozone (triatomic oxygen) was initiated in the 19th century. Ozone has m