Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sonya Pritchard"'
Autor:
Bruce Ruggeri, Jean Husten, Robert L. Hudkins, Allison L. Zulli, Candace S. Worrell, Mark A. Ator, Ralph E. Parchment, Natalie McGann, Hong Chang, Jennifer Grobelny, Sonya Pritchard, Sheila J. Miknyoczki, James Deibold
Publikováno v:
Molecular cancer therapeutics. 6(8)
The effect of the potent and selective poly(ADP-ribose) (PAR) polymerase-1 [and PAR polymerase-2] inhibitor CEP-8983 on the ability to sensitize chemoresistant glioblastoma (RG2), rhabdomyosarcoma (RH18), neuroblastoma (NB1691), and colon carcinoma (
Autor:
Hugh Zhao, Hong Chang, Susan Jones-Bolin, Pawel Dobrzanski, Candy Robinson, Bruce Ruggeri, Kathryn Hunter, Sonya Pritchard
Publikováno v:
Cancer research. 64(3)
Tumor-associated angiogenesis is critical for tumor growth and metastasis and is controlled by various pro- and antiangiogenic factors. The Eph family of receptor tyrosine kinases has emerged as one of the pivotal regulators of angiogenesis. Here we
Autor:
Sheila J, Miknyoczki, Susan, Jones-Bolin, Sonya, Pritchard, Kathryn, Hunter, Hugh, Zhao, Weihua, Wan, Mark, Ator, Ronald, Bihovsky, Robert, Hudkins, Sankar, Chatterjee, Andres, Klein-Szanto, Craig, Dionne, Bruce, Ruggeri
Publikováno v:
Molecular cancer therapeutics. 2(4)
Poly(ADP-ribose) polymerase 1 (PARP-1) is a nuclear zinc finger DNA-binding protein that is implicated in the repair of DNA damage. Inhibition of PARP-1 through genetic knockouts causes cells to become hypersensitive to various chemotherapeutic agent