Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sonya G. Wilson"'
Autor:
Jorge D. Brioni, Peter R. Hollingsworth, Sonya G. Wilson, Michael W. Decker, Prisca Honore, Robert B. Moreland, Gin C. Hsieh, Odile EI-Kouhen, Chang Z. Zhu, Renjie Chang, Joe Mikusa
Publikováno v:
Pain. 114:195-202
Metabotropic glutamate receptors (mGluRs) have previously been shown to play a role in pain transmission during inflammatory or neuropathic pain states. However, the role of mGluR5 in post-operative pain remains to be fully investigated. The present
Autor:
Prisca Honore, Joseph P. Mikusa, Donna M. Gauvin, Michael W. Decker, Chang Z. Zhu, Sonya G. Wilson, Carol T. Wismer, Carrie L. Wade, James J. Lynch
Publikováno v:
European Journal of Pharmacology. 506:107-118
Preclinical data, performed in a limited number of pain models, suggest that functional blockade of metabotropic glutamate (mGlu) receptors may be beneficial for pain management. In the present study, effects of 2-methyl-6-(phenylethynyl)-pyridine (M
The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans
Autor:
Alexander V. Mayorov, Kumar V.S. Nemmani, Roger B. Fillingim, Toni L. Glover, M. Kristina Groce, Judith E. Grisel, Sonya G. Wilson, Roland Staud, Magda Stankova, Lee M. Kaplan, Andrew L. Rankin, Margaret R. Wallace, Jeffrey S. Mogil, Victor J. Hruby, Elissa J. Chesler, William R. Lariviere, Timothy J. Ness
Publikováno v:
Proceedings of the National Academy of Sciences. 100:4867-4872
Sex specificity of neural mechanisms modulating nociceptive information has been demonstrated in rodents, and these qualitative sex differences appear to be relevant to analgesia from κ-opioid receptor agonists, a drug class reported to be clinicall
Autor:
Sandra L. Rodriguez-Zas, William R. Lariviere, Sonya G. Wilson, Jeffrey S. Mogil, Elissa J. Chesler
Publikováno v:
Neuroscience & Biobehavioral Reviews. 26:907-923
Laboratory conditions in biobehavioral experiments are commonly assumed to be ‘controlled’, having little impact on the outcome. However, recent studies have illustrated that the laboratory environment has a robust effect on behavioral traits. Gi
Publikováno v:
The Journal of Pain. 3:181-189
The formalin test is commonly used as a model of persistent pain. Besides producing pain behavior, hind paw formalin injection induces the expression of the immediate-early gene, c- fos . A current controversy is whether noxious stimulus-induced Fos
Autor:
Seetal M. Adhikari, Tinna M. Laughlin, William R. Lariviere, Sonya G. Wilson, Erin E. West, Anna Kokayeff, You Wan, Jeffrey S. Mogil
Publikováno v:
Pain. 97:75-86
We and others have previously demonstrated that nociception in the mouse is heritable. A genetic correlation analysis of 12 common measures of nociception among a common set of inbred strains revealed three major clusters (or 'types') of nociception
Autor:
Joel Z. Schwarz, Stanford B. Call, John K. Belknap, Michael R. Murray, Andrew L. Rankin, Sandra L. Rodriguez-Zas, Erin E. West, Elissa J. Chesler, Heather S. Hain, Sonya G. Wilson, Cory Teuscher, Jeffrey S. Mogil
Publikováno v:
Pain. 96:385-391
Sensitivity to pain is widely variable, and much of this variability is genetic in origin. The specific genes responsible have begun to be identified, but only for thermal nociception. In order to facilitate the identification of polymorphic, pain-re
Autor:
Sonya G. Wilson, Jeffrey S. Mogil
Publikováno v:
Behavioural Brain Research. 125:65-73
The increasing popularity of the mouse as a subject in basic science studies of pain can largely be attributed to the development of transgenic ‘knockout’ technology in this species only. To take advantage of this biological technique, many inves
Publikováno v:
Pharmacogenetics and Genomics. 9:619-626
The ability to predict interindividual differences in drug efficacy or toxicity, based on genetic factors that influence drug disposition or drug action, is fast becoming a realistic goal. The purpose of the present study was to determine whether epi
Publikováno v:
Neuroscience Letters. 261:147-150
Despite much study since its discovery in 1995, the effects of orphanin FQ/nociceptin (OFQ/N), the endogenous ligand of the `orphan' opioid receptor, on nociceptive sensitivity remain unclear. Different laboratories have variously reported hyperalges