Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sony Soman"'
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175118 (2017)
Preeclampsia (PE) is a gestational disorder, manifested in the second half of pregnancy by maternal hypertension, proteinuria and generalized edema. PE is a major cause of maternal and fetal morbidity and mortality, accounting for nearly 40% of all p
Externí odkaz:
https://doaj.org/article/2c8163af395744edaa7d110463f24245
Autor:
Michael C. Petriello, Sony Soman, Manjula Sunkara, Bernhard Hennig, Marian Pavuk, Linda S. Birnbaum, Richard Charnigo, Andrew J. Morris
Publikováno v:
Environmental Research. 162:211-218
Trimethylamine N-oxide (TMAO) is a diet and gut microbiota-derived metabolite that has been linked to cardiovascular disease risk in human studies and animal models. TMAO levels show wide inter and intra individual variability in humans that can like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af12557d7ebcbf94b1ce6d01b08f7bd7
https://doi.org/10.1016/j.envres.2018.01.007
https://doi.org/10.1016/j.envres.2018.01.007
Autor:
Ahmed Abdel-Latif, Michael C. Petriello, Liping Yang, Banrida Wahlang, Andrew J. Morris, Himi Tripathi, Jazmyne Barney, Sony Soman, Bernhard Hennig, Eun Y. Lee, Xiang Ye, Jessie B. Hoffman, Chunyan Wang, J. Anthony Brandon, Xiang-An Li
Publikováno v:
Toxicological Sciences. 162:548-558
Exposure to dioxins and related persistent organic pollutants likely contributes to cardiovascular disease (CVD) risk through multiple mechanisms including the induction of chronic inflammation. Epidemiological studies have shown that leaner individu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e88994ba1abcba709a88a45cad2aff
https://doi.org/10.1093/toxsci/kfx275
https://doi.org/10.1093/toxsci/kfx275
Autor:
Simon J. F. Macdonald, Willem-Jan Keune, Tatjana Heidebrecht, Fernando Salgado-Polo, Ahmed Abdel Latif, Craig Jamieson, Andrew J. Morris, Anastassis Perrakis, Sony Soman, Lakshman Chelvarajan, Frances Potjewyd, Allan J. B. Watson
Publikováno v:
Journal of Medicinal Chemistry. 60:2006-2017
Autotaxin produces the bioactive lipid lysophosphatidic acid (LPA), and is a drug target of considerable interest for numerous pathologies. We report the expedient, structure-guided evolution of weak physiological allosteric inhibitors (bile salts) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6ac11a2ba5be89d16af98070e874e66
https://doi.org/10.1021/acs.jmedchem.6b01743
https://doi.org/10.1021/acs.jmedchem.6b01743
Autor:
Victoria L. English, Nika Larian, Erin N. Jackson, Kevin J. Pearson, Jiaying Weng, Andrew J. Morris, Sean E. Thatcher, Sony Soman, Hollie I. Swanson, Arnold J. Stromberg, Lisa A. Cassis
Publikováno v:
Environmental Health Perspectives
Lipophilic polychlorinated biphenyls (PCBs) accumulate with obesity, but during weight loss, liberated PCBs act as ligands of the aryl hydrocarbon receptor (AhR) to negatively influence health. Previous studies demonstrated that PCB-77 administration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::064e97fc054b6ba5d13a3b4fac8cb391
https://doi.org/10.1289/ehp4133
https://doi.org/10.1289/ehp4133
Autor:
Fredrick O. Onono, Ebubechi Adindu, Baoxiang Yan, Sony Soman, Courtney Hammill, Andrew J. Morris
Publikováno v:
Cancer Research. 79:3601-3601
Lysophosphatidic acid (LPA) is a pleiotropic growth-factor lysophospholipid that promotes cancer cell survival, growth, migration, invasion, metastasis, and resistance to chemotherapy and radiotherapy. The main precursor for LPA, lysophosphatidylchol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19e8d2ff7491ef480dd938f21e4de65d
https://doi.org/10.1158/1538-7445.am2019-3601
https://doi.org/10.1158/1538-7445.am2019-3601
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175118 (2017)
PLoS ONE
PLoS ONE
Introduction Preeclampsia (PE) is a gestational disorder, manifested in the second half of pregnancy by maternal hypertension, proteinuria and generalized edema. PE is a major cause of maternal and fetal morbidity and mortality, accounting for nearly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb966ec87b5c297409f9d80ac843d2c8
http://europepmc.org/articles/PMC5383057?pdf=render
http://europepmc.org/articles/PMC5383057?pdf=render
Autor:
Andrew J. Morris, Manjula Sunkara, J. Brandon, Susan S. Smyth, Sony Soman, Fredrick O. Onono, Paul Mueller
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36
Diet-dependent obesity is a risk factor for coronary artery disease and a powerful risk factor for some cancers particularly in women. One mechanism that has been proposed to link diet-dependent obesity to disease is that diets high in fats and lipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fcfc063df0df89cca4653455b2b0f39
https://doi.org/10.1161/atvb.36.suppl_1.396
https://doi.org/10.1161/atvb.36.suppl_1.396
Publikováno v:
Mechanisms of Ageing and Development. 132:443-448
Previous studies show increased oxidative DNA and RNA damage and diminished 8-oxoguanine glycosylase (OGG1) mediated base excision repair in vulnerable brain regions of mild cognitive impairment and late-stage Alzheimer's disease (LAD) subjects compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bace8a753ab5ceefc193d615009190a2
https://doi.org/10.1016/j.mad.2011.08.003
https://doi.org/10.1016/j.mad.2011.08.003
Publikováno v:
Journal of chromatography. A. 1269
Various organic-based monoliths were prepared and optimized for immobilization of the protein human serum albumin (HSA) as a binding agent for chiral separations and high-performance affinity chromatography. These monoliths contained co-polymers base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5cf804cb4c07499a217fcf3dd912eb
https://pubmed.ncbi.nlm.nih.gov/23010249
https://pubmed.ncbi.nlm.nih.gov/23010249