A Comparison Between Recombinant Listeria GAPDH Proteins and GAPDH Encoding mRNA Conjugated to Lipids as Cross-Reactive Vaccines for Listeria, Mycobacterium, and Streptococcus

Autor: Hector Teran-Navarro, David Salcines-Cuevas, Ricardo Calderon-Gonzalez, Raquel Tobes, Jorge Calvo-Montes, Inmaculada Concepción Pérez-Del Molino Bernal, Sonsoles Yañez-Diaz, Manuel Fresno, Carmen Alvarez-Dominguez

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Cross-reactive vaccines recognize common molecular patterns in pathogens and are able to confer broad spectrum protection against different infections. Antigens common to pathogenic bacteria that induce broad immune responses, such as the glyceraldeh

Externí odkaz: https://doaj.org/article/a41c4dc468da4c2d89cb65d45e5a75db

Pre-clinical development of Listeria-based nanovaccines as immunotherapies for solid tumours: insights from melanoma

Autor: Hector Terán-Navarro, Ricardo Calderon-Gonzalez, David Salcines-Cuevas, Isabel García, Marco Marradi, Javier Freire, Erwan Salmon, Mar Portillo-Gonzalez, Elisabet Frande-Cabanes, Almudena García-Castaño, Virginia Martinez-Callejo, Javier Gomez-Roman, Raquel Tobes, Fernando Rivera, Sonsoles Yañez-Diaz, Carmen Álvarez-Domínguez

Publikováno v: OncoImmunology, Vol 8, Iss 2 (2019)

Gold glyconanoparticles loaded with the listeriolysin O peptide 91–99 (GNP-LLO91-99), a bacterial peptide with anti-metastatic properties, are vaccine delivery platforms facilitating immune cell targeting and increasing antigen loading. Here, we pr

Externí odkaz: https://doaj.org/article/1f27fc9b9d0441b78d7ab7e29e2b2a5b

A novel therapy for melanoma developed in mice: transformation of melanoma into dendritic cells with Listeria monocytogenes.

Autor: Lucia Bronchalo-Vicente, Estela Rodriguez-Del Rio, Javier Freire, Ricardo Calderon-Gonzalez, Elisabet Frande-Cabanes, Jose Javier Gomez-Roman, Hector Fernández-Llaca, Sonsoles Yañez-Diaz, Carmen Alvarez-Dominguez

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0117923 (2015)

Listeria monocytogenes is a gram-positive bacteria and human pathogen widely used in cancer immunotherapy because of its capacity to induce a specific cytotoxic T cell response in tumours. This bacterial pathogen strongly induces innate and specific

Externí odkaz: https://doaj.org/article/c2637bd9c4304389a51064a5074524b4

Glyceraldehyde-3-phosphate Dehydrogenase Common Peptides of Listeria monocytogenes, Mycobacterium marinum and Streptococcus pneumoniae as Universal Vaccines

Autor: Sonsoles Yañez-Diaz, Jorge Calvo-Montes, David Salcines-Cuevas, Carmen Alvarez-Dominguez, Paula Torres-Rodriguez, Ricardo Calderon-Gonzalez, Manuel Fresno, I. Concepción Pérez Del Molino-Bernal, Hector Teran-Navarro, Raquel Tobes

Publikováno v: Vaccines
Volume 9
Issue 3
Vaccines, Vol 9, Iss 269, p 269 (2021)
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Digital.CSIC. Repositorio Institucional del CSIC

Universal vaccines can be prepared with antigens common to different pathogens. In this regard, the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a common virulence factor among pathogenic bacteria of the genera Listeria, Mycobacterium and Stre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8973b7f99fd03bbf7f8aa5bcb37f7af8

GNP-GAPDH1-22 nanovaccines prevent neonatal listeriosis by blocking microglial apoptosis and bacterial dissemination

Autor: Sonsoles Yañez-Diaz, Fernando Rivera, Hector Teran-Navarro, Javier Gómez-Román, Isabel García, Claudia González-Rico, Carmen Alvarez-Dominguez, Manuel Fresno, Soledad Penadés, Javier Freire, Marco Marradi, David Salcines-Cuevas, Carmen Punzón, Elisabet Frande-Cabanes, Ana Castañeda-Sampedro, Ricardo Calderon-Gonzalez, M. Carmen Fariñas, José María Marimón, Mirian Alkorta-Gurrutxaga, Aida San Nicolas-Gomez

Publikováno v: Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Oncotarget. 2017 Jul 20;8(33):53916-53934
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)

Clinical cases of neonatal listeriosis are associated with brain disease and fetal loss due to complications in early or late pregnancy, which suggests that microglial function is altered. This is believed to be the first study to link microglial apo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd59113e83e6461d6eb08fd124e6212
https://doi.org/10.18632/oncotarget.19405