Synthesis and evaluation of benzoylbenzofurans and isoflavone derivatives as sirtuin 1 inhibitors with antiproliferative effects on cancer cells.

Autor: Selepe MA; Department of Chemistry, University of Pretoria, Lynnwood Rd, Hatfield, Pretoria 0002, South Africa. Electronic address: mamoalosi.selepe@up.ac.za., Kunyane P; Department of Chemistry, University of Pretoria, Lynnwood Rd, Hatfield, Pretoria 0002, South Africa., Seboletswe P; School of Chemistry and Physics, University of KwaZulu-Natal, P/Bag X54001, Westville, Durban 4000, South Africa., Nair S; Radiation Biophysics Division, Separated Sector Cyclotron Laboratory, NRF-iThemba LABS, Cape Town 7131, South Africa., Cele N; School of Chemistry and Physics, University of KwaZulu-Natal, P/Bag X54001, Westville, Durban 4000, South Africa., Engelbrecht M; Radiation Biophysics Division, Separated Sector Cyclotron Laboratory, NRF-iThemba LABS, Cape Town 7131, South Africa., Joubert DF; Department of Physiology, University of Pretoria, Lynnwood Rd, Hatfield, Pretoria 0002, South Africa., Vandevoorde C; Radiation Biophysics Division, Separated Sector Cyclotron Laboratory, NRF-iThemba LABS, Cape Town 7131, South Africa., Singh P; School of Chemistry and Physics, University of KwaZulu-Natal, P/Bag X54001, Westville, Durban 4000, South Africa. Electronic address: Singhp4@ukzn.ac.za., Sonopo MS; Radiochemistry, South African Nuclear Energy Corporation Ltd, Pelindaba, Brits 0240, South Africa. Electronic address: Molahlehi.Sonopo@necsa.co.za.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2022 Nov; Vol. 128, pp. 106101. Date of Electronic Publication: 2022 Aug 17.

Synthesis and Antifungal Activity of Chromones and Benzoxepines from the Leaves of Ptaeroxylon obliquum .

Autor: Malefo MS; Department of Chemistry, University of Pretoria, Lynnwood Road, Hatfield, Pretoria 0002, South Africa., Ramadwa TE; Phytomedicine Programme, Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, Pretoria 0110, South Africa., Famuyide IM; Phytomedicine Programme, Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, Pretoria 0110, South Africa., McGaw LJ; Phytomedicine Programme, Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, Pretoria 0110, South Africa., Eloff JN; Phytomedicine Programme, Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, Pretoria 0110, South Africa., Sonopo MS; Radiochemistry, South African Nuclear Energy Corporation (Necsa), Pelindaba, Brits R104, South Africa., Selepe MA; Department of Chemistry, University of Pretoria, Lynnwood Road, Hatfield, Pretoria 0002, South Africa.

Publikováno v: Journal of natural products [J Nat Prod] 2020 Aug 28; Vol. 83 (8), pp. 2508-2517. Date of Electronic Publication: 2020 Aug 13.

Synthesis of Isoflavones by Tandem Demethylation and Ring-Opening/Cyclization of Methoxybenzoylbenzofurans.

Autor: Kunyane P; Department of Chemistry , University of Pretoria , Lynnwood Road , Hatfield , Pretoria 0002 , South Africa., Sonopo MS; Radiochemistry , South African Nuclear Energy Corporation (Necsa) , Pelindaba , Brits 0240 , South Africa., Selepe MA; Department of Chemistry , University of Pretoria , Lynnwood Road , Hatfield , Pretoria 0002 , South Africa.

Publikováno v: Journal of natural products [J Nat Prod] 2019 Nov 22; Vol. 82 (11), pp. 3074-3082. Date of Electronic Publication: 2019 Nov 08.

Carbon-14 radiolabelling and tissue distribution evaluation of a potential anti-TB compound.

Autor: Sonopo MS; Radiochemistry, Necsa, P. O. Box 482, Pretoria, 0001, South Africa., Venter K; Medical Research Council of South Africa, Pretoria, South Africa., Winks S; iThemba Pharmaceuticals (Pty) Ltd, Johannesburg, South Africa., Marjanovic-Painter B; Radiochemistry, Necsa, P. O. Box 482, Pretoria, 0001, South Africa., Morgans GL; iThemba Pharmaceuticals (Pty) Ltd, Johannesburg, South Africa., Zeevaart JR; DST/NWU, Preclinical Drug Development Platform, North West University, Potchefstroom, South Africa.

Publikováno v: Journal of labelled compounds & radiopharmaceuticals [J Labelled Comp Radiopharm] 2016 Jun 15; Vol. 59 (7), pp. 264-9. Date of Electronic Publication: 2016 Apr 24.