Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sonoko Chikamatsu"'
Autor:
Sonoko Chikamatsu, Ken Saijo, Hiroo Imai, Koichi Narita, Yoshifumi Kawamura, Tadashi Katoh, Chikashi Ishioka
Publikováno v:
Cancer Medicine, Vol 8, Iss 12, Pp 5662-5672 (2019)
Abstract Liphagal, isolated from the marine sponge Aka coralliphaga, exhibits phosphatidylinositol 3‐kinase alpha (PI3Kα) inhibitory activity and cytotoxic effects in human cancer cells. Siphonodictyal B, the biogenetic precursor of liphagal, also
Externí odkaz:
https://doaj.org/article/13552b373c0c4621a3f1069c9620e2f0
Autor:
Masahiro Takahashi, Masanobu Takahashi, Keigo Komine, Hideharu Yamada, Yuki Kasahara, Sonoko Chikamatsu, Akira Okita, Shukuei Ito, Kota Ouchi, Yoshinari Okada, Hiroo Imai, Ken Saijo, Hidekazu Shirota, Shin Takahashi, Takahiro Mori, Hideki Shimodaira, Chikashi Ishioka
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179694 (2017)
Some elderly cancer patients, even with good Eastern Cooperative Oncology Group performance status (ECOG-PS), have poor survival outcomes and cannot tolerate standard therapy. Few studies have detailed the associations between the G8 screening tool,
Externí odkaz:
https://doaj.org/article/7428c8e7332240c4aa5164edec14e8a0
Publikováno v:
Cancer Science
Phosphatidylinositol‐3 kinase (PI3K) inhibitor and histone deacetylase (HDAC) inhibitor have been developed as potential anticancer drugs. However, the cytotoxicity of PI3K inhibitor or HDAC inhibitor alone is relatively weak. We recently developed
Autor:
Yoshikazu Takahashi, Akira Okita, Keigo Komine, Masahiro Takahashi, Kota Ouchi, Sonoko Chikamatsu, Yoshinari Okada, Sadayuki Kawai, Yuki Kasahara, Hidekazu Shirota, Chikashi Ishioka, Hiroo Imai, Ken Saijo, Masanobu Takahashi, Shin Takahashi, Makio Gamoh, Shukuei Ito
Publikováno v:
International Journal of Clinical Oncology
Background Recombinant human soluble thrombomodulin (rTM) has been established and introduced in the clinic as a standard treatment for disseminated intravascular coagulation (DIC). However, the efficacy and safety of rTM for DIC associated with soli
Publikováno v:
Cancer Science
Histone deacetylase (HDAC)/phosphatidylinositol 3-kinase (PI3K) dual inhibition is a promising strategy for the treatment of intractable cancers because of the advantages of overcoming potential resistance and showing synergistic effects. Therefore,
Autor:
Sonoko Chikamatsu, Ken Saijo, Hiroo Imai, Koichi Narita, Yoshifumi Kawamura, Tadashi Katoh, Chikashi Ishioka
Publikováno v:
Cancer Medicine. 8
The cover image is based on the original research In Vitro and in Vivo antitumor activity and the mechanism of siphonodictyal B in human colon cancer cells by Sonoko Chikamatsu et al., https://doi.org/10.1002/cam4.2409. Cover image © Sonojo Chikamat
Autor:
Chikashi Ishioka, Yoshinari Okada, Yuki Kasahara, Masahiro Takahashi, Shin Takahashi, Ken Saijo, Akira Okita, Hidekazu Shirota, Akihiro Kobayashi, Masanobu Takahashi, Takayuki Oishi, Hideki Shimodaira, Sonoko Chikamatsu, Hiroo Imai, Keigo Komine
Publikováno v:
Chemotherapy. 61:262-268
Background: Incomplete cross-resistances between paclitaxel (PTX) and docetaxel (DTX) has been demonstrated in several types of cancer. The objective of the present study was to assess the existence of cross-resistance between PTX and DTX in esophage
Autor:
Koichi Narita, Yoshifumi Kawamura, Chikashi Ishioka, Sonoko Chikamatsu, Tadashi Katoh, Ken Saijo, Hiroo Imai
Publikováno v:
Cancer Medicine
Cancer Medicine, Vol 8, Iss 12, Pp 5662-5672 (2019)
Cancer Medicine, Vol 8, Iss 12, Pp 5662-5672 (2019)
Liphagal, isolated from the marine sponge Aka coralliphaga, exhibits phosphatidylinositol 3‐kinase alpha (PI3Kα) inhibitory activity and cytotoxic effects in human cancer cells. Siphonodictyal B, the biogenetic precursor of liphagal, also has PI3K
Autor:
Keigo Komine, Masahiro Takahashi, Hidekazu Shirota, Hideki Shimodaira, Yuki Kasahara, Hiroo Imai, Chikashi Ishioka, Sonoko Chikamatsu, Yoshinari Okada, Takahiro Mori, Shukuei Ito, Masanobu Takahashi, Kota Ouchi, Shin Takahashi, Ken Saijo, Hideharu Yamada, Akira Okita
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 6, p e0179694 (2017)
PLoS ONE, Vol 12, Iss 6, p e0179694 (2017)
Background Some elderly cancer patients, even with good Eastern Cooperative Oncology Group performance status (ECOG-PS), have poor survival outcomes and cannot tolerate standard therapy. Few studies have detailed the associations between the G8 scree
Autor:
Masanobu Takahashi, Yoshifumi Kawamura, Yoshinari Okada, Ken Saijo, Akira Okita, Hiroo Imai, Masahiro Takahashi, Sakura Hiraide, Yuki Kasahara, Hidekazu Shirota, Hideharu Yamada, Chikashi Ishioka, Sho Umegaki, Sonoko Chikamatsu, Keigo Komine
Publikováno v:
Annals of Oncology. 29:vii8