Cellular Models of Alpha-Synuclein Aggregation: What Have We Learned and Implications for Future Study.

Autor: Albert K; A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210 Kuopio, Finland., Kälvälä S; A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210 Kuopio, Finland., Hakosalo V; A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210 Kuopio, Finland., Syvänen V; A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210 Kuopio, Finland., Krupa P; A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210 Kuopio, Finland., Niskanen J; A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210 Kuopio, Finland., Peltonen S; A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210 Kuopio, Finland., Sonninen TM; A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210 Kuopio, Finland., Lehtonen Š; A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210 Kuopio, Finland.; Neuroscience Center, University of Helsinki, 00014 Helsinki, Finland.

Publikováno v: Biomedicines [Biomedicines] 2022 Oct 20; Vol. 10 (10). Date of Electronic Publication: 2022 Oct 20.

Generation of a human induced pluripotent stem cell line (UEFi003-A) carrying heterozygous A673T variant in amyloid precursor protein associated with a reduced risk of Alzheimer's disease.

Autor: Rolova T; Neuroscience Center, University of Helsinki, Helsinki, Finland., Wu YC; Neuroscience Center, University of Helsinki, Helsinki, Finland., Koskuvi M; Neuroscience Center, University of Helsinki, Helsinki, Finland; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Voutilainen J; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Sonninen TM; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio University Hospital, Kuopio, Finland., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio University Hospital, Kuopio, Finland., Hämäläinen RH; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Koistinaho J; Neuroscience Center, University of Helsinki, Helsinki, Finland; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Lehtonen Š; Neuroscience Center, University of Helsinki, Helsinki, Finland; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland. Electronic address: sarka.lehtonen@uef.fi.

Publikováno v: Stem cell research [Stem Cell Res] 2020 Oct; Vol. 48, pp. 101968. Date of Electronic Publication: 2020 Sep 02.

Metabolic alterations in Parkinson's disease astrocytes.

Autor: Sonninen TM; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Neulaniementie 2, 70211, Kuopio, Finland., Hämäläinen RH; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Neulaniementie 2, 70211, Kuopio, Finland., Koskuvi M; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Neulaniementie 2, 70211, Kuopio, Finland., Oksanen M; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Neulaniementie 2, 70211, Kuopio, Finland., Shakirzyanova A; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Neulaniementie 2, 70211, Kuopio, Finland., Wojciechowski S; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Neulaniementie 2, 70211, Kuopio, Finland., Puttonen K; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Neulaniementie 2, 70211, Kuopio, Finland., Naumenko N; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Neulaniementie 2, 70211, Kuopio, Finland., Goldsteins G; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Neulaniementie 2, 70211, Kuopio, Finland., Laham-Karam N; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Neulaniementie 2, 70211, Kuopio, Finland., Lehtonen M; School of Pharmacy, University of Eastern Finland, Kuopio, Finland.; LC-MS Metabolomics Center, Biocenter Kuopio, Kuopio, Finland., Tavi P; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Neulaniementie 2, 70211, Kuopio, Finland., Koistinaho J; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Neulaniementie 2, 70211, Kuopio, Finland.; Neuroscience Center, University of Helsinki, Haartmaninkatu 8, 00014, Helsinki, Finland., Lehtonen Š; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Neulaniementie 2, 70211, Kuopio, Finland. sarka.lehtonen@uef.fi.; Neuroscience Center, University of Helsinki, Haartmaninkatu 8, 00014, Helsinki, Finland. sarka.lehtonen@uef.fi.

Publikováno v: Scientific reports [Sci Rep] 2020 Sep 02; Vol. 10 (1), pp. 14474. Date of Electronic Publication: 2020 Sep 02.

Generation of a human induced pluripotent stem cell line from a patient with a rare A673T variant in amyloid precursor protein gene that reduces the risk for Alzheimer's disease.

Autor: Lehtonen Š; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland; Neuroscience Center, University of Helsinki, Finland., Höytyläinen I; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Voutilainen J; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Sonninen TM; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio University Hospital, Kuopio, Finland., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio University Hospital, Kuopio, Finland., Hämäläinen RH; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Oksanen M; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Koistinaho J; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland; Neuroscience Center, University of Helsinki, Finland. Electronic address: jari.koistinaho@uef.fi.

Publikováno v: Stem cell research [Stem Cell Res] 2018 Jul; Vol. 30, pp. 96-99. Date of Electronic Publication: 2018 May 19.