Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sonnet J.H. Arlander"'
Supplementary Figure Legends 1-3 from DNA Protein Kinase–Dependent G2 Checkpoint Revealed following Knockdown of Ataxia-Telangiectasia Mutated in Human Mammary Epithelial Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe0bd1414df86a609e623627afce200
https://doi.org/10.1158/0008-5472.22371335.v1
https://doi.org/10.1158/0008-5472.22371335.v1
Members of the phosphatidylinositol 3-kinase–related kinase family, in particular the ataxia-telangiectasia mutated (ATM) kinase and the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs), regulate cellular responses to DNA double-str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2aefa2c8d816f217535b684b1954b81
https://doi.org/10.1158/0008-5472.c.6496751
https://doi.org/10.1158/0008-5472.c.6496751
Supplementary Figure 3 from DNA Protein Kinase–Dependent G2 Checkpoint Revealed following Knockdown of Ataxia-Telangiectasia Mutated in Human Mammary Epithelial Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b8e63065676cb43b631163ec1348de
https://doi.org/10.1158/0008-5472.22371338
https://doi.org/10.1158/0008-5472.22371338
Supplementary Figure 2 from DNA Protein Kinase–Dependent G2 Checkpoint Revealed following Knockdown of Ataxia-Telangiectasia Mutated in Human Mammary Epithelial Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6269d063ab8030a4519ff872ff7be496
https://doi.org/10.1158/0008-5472.22371341
https://doi.org/10.1158/0008-5472.22371341
Supplementary Figure 1 from DNA Protein Kinase–Dependent G2 Checkpoint Revealed following Knockdown of Ataxia-Telangiectasia Mutated in Human Mammary Epithelial Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856ab420591afc8ea8727df509945761
https://doi.org/10.1158/0008-5472.22371344
https://doi.org/10.1158/0008-5472.22371344
Autor:
Yingchun Zhou, Dennis A. Simpson, Sonnet J.H. Arlander, Marila Cordeiro-Stone, Tong Zhou, Jacquelyn J. Bower, William K. Kaufmann, Richard S. Paules
Publikováno v:
Cell Cycle. 9:1617-1628
The decatenation G2 checkpoint is proposed to delay cellular progression from G2 into mitosis when intertwined daughter chromatids are insufficiently decatenated. Previous studies indicated that the ATM- and Rad3-related (ATR) checkpoint kinase, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::750a61806876358f0aab3f8bb887f0c4
https://doi.org/10.4161/cc.9.8.11470
https://doi.org/10.4161/cc.9.8.11470
Publikováno v:
Cancer Research. 68:89-97
Members of the phosphatidylinositol 3-kinase–related kinase family, in particular the ataxia-telangiectasia mutated (ATM) kinase and the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs), regulate cellular responses to DNA double-str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e471839ac01f9415d75c2ca06259b328
https://doi.org/10.1158/0008-5472.can-07-0675
https://doi.org/10.1158/0008-5472.can-07-0675
Autor:
Kevin M. Hopkins, Jennifer S. Hackbarth, Howard B. Lieberman, Junjie Chen, Yong Un Baek, Sonnet J.H. Arlander, Karen S. Flatten, Jill M. Wagner, Scott H. Kaufmann, M. Bijoy Thomas, David A. Loegering, Benjamin T. Vroman, William A. Cliby, Larry M. Karnitz
Publikováno v:
Molecular Pharmacology. 68:1636-1644
Two signaling pathways are activated by antineoplastic therapies that damage DNA and stall replication. In one pathway, double-strand breaks activate ataxia-telangiectasia mutated kinase (ATM) and checkpoint kinase 2 (Chk2), two protein kinases that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37aa34f018f32f3c981aa7025a7622e6
https://doi.org/10.1124/mol.105.012716
https://doi.org/10.1124/mol.105.012716
Autor:
B. Douglas Smith, Nga T. Dai, Heather Powell, Benjamin T. Vroman, David A. Loegering, Judith E. Karp, Karen S. Flatten, Charles Erlichman, Scott H. Kaufmann, Ruben A. Mesa, Larry M. Karnitz, Sonnet J.H. Arlander, Cynthia Ten Eyck, Michael P. Heldebrant
Publikováno v:
Blood. 106:318-327
Previous studies demonstrated that ataxia telangiectasia mutated– and Rad3-related (ATR) kinase and its downstream target checkpoint kinase 1 (Chk1) facilitate survival of cells treated with nucleoside analogs and other replication inhibitors. Rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e1a763aa89ea4f7bb15dd86cb5f150
https://doi.org/10.1182/blood-2004-09-3523
https://doi.org/10.1182/blood-2004-09-3523
Publikováno v:
DNA Repair. 3:1009-1014
Genotoxic stress activates checkpoint signaling pathways that block cell cycle progression, trigger apoptosis, and regulate DNA repair. Studies in yeast and humans have shown that Rad9, Hus1, Rad1, and Rad17 play key roles in checkpoint activation. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3ff7b7b331a4e48b129ffff2dd2037
https://doi.org/10.1016/j.dnarep.2004.03.032
https://doi.org/10.1016/j.dnarep.2004.03.032