Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sonja Witzel"'
Autor:
Verena Krähling, Stephanie Erbar, Alexandra Kupke, Sara S. Nogueira, Kerstin C. Walzer, Hendrik Berger, Erik Dietzel, Sandro Halwe, Cornelius Rohde, Lucie Sauerhering, Letícia Aragão-Santiago, Jorge Moreno Herrero, Sonja Witzel, Heinrich Haas, Stephan Becker, Ugur Sahin
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy.
Emerging and re-emerging viruses, such as Zaire Ebola virus (EBOV), pose a global threat and require immediate countermeasures, including the rapid development of effective vaccines that are easy to manufacture. Synthetic self-amplifying RNAs (saRNAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::421159fbb7876f703e67312842f660cb
https://pubmed.ncbi.nlm.nih.gov/36303436
https://pubmed.ncbi.nlm.nih.gov/36303436
Autor:
Kuldeep Singh, Natalia Malkova, Christian Hotz, Jan Diekmann, Gang Zheng, Sonja Witzel, Michelle Callahan, Qunyan Yu, Hui Qu, Joanne Lager, Dinesh S. Bangari, Serena Masciari, Gary J. Nabel, Julia Schlereth, Yu-an Zhang, Andreas Kuhn, Dmitri Wiederschain, Karl Hsu, Ugur Sahin, Marie Bernardo, Mustafa Diken, Mikhail Levit, Friederike Gieseke, Andy Hebert, Bodo Tillmann, Abderaouf Selmi, Jack Pollard, Sue Ryan, Christian Grunwitz, Fangxian Sun, Katalin Karikó, Lena Wicke, Hui Cao, William Weber, Timothy R. Wagenaar, Sebastian Kreiter, Tatiana Tolstykh
Publikováno v:
Cancer Cell
Local immunotherapy ideally stimulates immune responses against tumors while avoiding toxicities associated with systemic administration. Current strategies for tumor-targeted, gene-based delivery, however, are limited by adverse effects such as off-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ad00a44220c5d4522fd2289ce47795
https://doi.org/10.1126/scitranslmed.abc7804
https://doi.org/10.1126/scitranslmed.abc7804
Autor:
Sonja Witzel, Leonard Kaps, Tim Beissert, Christian Grunwitz, Yasmin Abassi, Patricia Gomes, Heinrich Haas, Sebastian Rosigkeit, Geethanjali Pickert, Fulvia Vascotto, Martin Meng, Jasmin Röder, Andreas Kuhn, Mustafa Diken, Andreas Kreft, Rosario Heck, Ugur Sahin, Nina Hayduk, Detlef Schuppan, Kira Ziegler, Ernesto Bockamp
Publikováno v:
Molecular pharmaceutics. 15(9)
Targeting mRNA to eukaryotic cells is an emerging technology for basic research and provides broad applications in cancer immunotherapy, vaccine development, protein replacement, and in vivo genome editing. Although a plethora of nanoparticles for ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b618edac37266dbedb6cfa87bdc5ea81
https://pubmed.ncbi.nlm.nih.gov/30028629
https://pubmed.ncbi.nlm.nih.gov/30028629
Autor:
Jan Diekmann, Jack Pollard, Sebastian Kreiter, Dmitri Wiederschain, Lena Wicke, Friederike Gieseke, Abderaouf Selmi, Timothy R. Wagenaar, Andreas Kuhn, Yu-an Zhang, Natalia Malkova, Hui Qu, Marie Jordan, Bodo Tillmann, Ugur Sahin, Gang Zheng, Christian Hotz, Tatiana Tolstykh, Fangxian Sun, Karl Hsu, Julia Schlereth, Serena Masciari, Hui Cao, Joanne Lager, Christian Grunwitz, Mustafa Diken, Gary J. Nabel, Andy Hebert, Sonja Witzel, Mikhail Levit, Qunyan Yu, Katalin Karikó
Publikováno v:
Cancer Research. 78:LB-130
Cancer immunotherapy localized to the tumor microenvironment holds great potential to promote innate and adaptive immune responses against tumors, while avoiding toxicities related to systemic administration of immuno-modulatory therapeutics. Current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caa99f28d7b11ec52234665def6c8f7c
https://doi.org/10.1158/1538-7445.am2018-lb-130
https://doi.org/10.1158/1538-7445.am2018-lb-130
Publikováno v:
ChemInform. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f6709f2960eda7397cbef74806280cf
https://doi.org/10.1002/chin.199819155
https://doi.org/10.1002/chin.199819155
Publikováno v:
Journal of Heterocyclic Chemistry. 34:1721-1723
The Synthesis of the title compound is described and its structure elucidated by 1H nmr spectroscopy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a636763e733bf0536e248ba2cd4e9ff7
https://doi.org/10.1002/jhet.5570340613
https://doi.org/10.1002/jhet.5570340613
Publikováno v:
ChemInform. 35
A series of 2′-nitroisoflavones 8–10, 15, 22, 27 and 28 was prepared via the (2-nitro-phenyl)-acetic acids 1, 13, 19 and 25. In order to obtain the corresponding 2′-aminoisoflavones the reduction of 8–10, 15, 22, 27 and 28 was undertaken. Sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c544174d9b9184534f0378ea3c2fd61
https://doi.org/10.1002/chin.200444125
https://doi.org/10.1002/chin.200444125