Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Sonja Welsch"'
Autor:
Iskander Khusainov, Natalie Romanov, Camille Goemans, Beata Turoňová, Christian E. Zimmerli, Sonja Welsch, Julian D. Langer, Athanasios Typas, Martin Beck
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Ribosomes translate the genetic code into proteins. Recent technical advances have facilitated in situ structural analyses of ribosome functional states inside eukaryotic cells and the minimal bacterium Mycoplasma. However, such analyses of
Externí odkaz:
https://doaj.org/article/1c4cdc672cfd47959501921623d1dff2
Autor:
Vinzent Schulz, Ralf Steinhilper, Jonathan Oltmanns, Sven-A. Freibert, Nils Krapoth, Uwe Linne, Sonja Welsch, Maren H. Hoock, Volker Schünemann, Bonnie J. Murphy, Roland Lill
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Maturation of iron-sulfur proteins in eukaryotes is initiated in mitochondria by the core iron-sulfur cluster assembly (ISC) complex, consisting of the cysteine desulfurase sub-complex NFS1-ISD11-ACP1, the scaffold protein ISCU2, the electro
Externí odkaz:
https://doaj.org/article/8ffd93ab41574bbc8173c92d34b5c889
Autor:
Patrick C. Hoffmann, Jan Philipp Kreysing, Iskander Khusainov, Maarten W. Tuijtel, Sonja Welsch, Martin Beck
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
The translational states of eukaryotic ribosomes have so far been only investigated in vitro. Here, authors obtained the 3.8 Å in situ 80S ribosome structure, the distribution of translational states and unique arrangement of rRNA expansion segments
Externí odkaz:
https://doaj.org/article/61565a935e9f4e16a4c80b3f1fb12c5e
Autor:
Tamara N. Grund, Yoshiki Kabashima, Tomoichirou Kusumoto, Di Wu, Sonja Welsch, Junshi Sakamoto, Hartmut Michel, Schara Safarian
Publikováno v:
Frontiers in Chemistry, Vol 10 (2023)
Cytochromes bd are essential for microaerobic respiration of many prokaryotes including a number of human pathogens. These enzymes catalyze the reduction of molecular oxygen to water using quinols as electron donors. Their importance for prokaryotic
Externí odkaz:
https://doaj.org/article/82fa77d068ce43f9890438abcd4bf1d7
Autor:
Schara Safarian, Helen K. Opel-Reading, Di Wu, Ahmad R. Mehdipour, Kiel Hards, Liam K. Harold, Melanie Radloff, Ian Stewart, Sonja Welsch, Gerhard Hummer, Gregory M. Cook, Kurt L. Krause, Hartmut Michel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
M. tuberculosis cytochrome bd oxidase is of interest as a TB drug target. Here, the authors present the 2.5 Å cryo-EM structure of M. tuberculosis cytochrome bd oxidase and identify a disulfide bond within the canonical quinol binding and oxidation
Externí odkaz:
https://doaj.org/article/d59d3dd24560451195a1764a95c9ea6d
Autor:
Kanwal Kayastha, Alexander Katsyv, Christina Himmrich, Sonja Welsch, Jan M Schuller, Ulrich Ermler, Volker Müller
Publikováno v:
eLife, Vol 11 (2022)
Lactate oxidation with NAD+ as electron acceptor is a highly endergonic reaction. Some anaerobic bacteria overcome the energetic hurdle by flavin-based electron bifurcation/confurcation (FBEB/FBEC) using a lactate dehydrogenase (Ldh) in concert with
Externí odkaz:
https://doaj.org/article/e81572dee7df4488a0400afc5d9a5796
Autor:
Olga Dolnik, Larissa Kolesnikova, Sonja Welsch, Thomas Strecker, Gordian Schudt, Stephan Becker
Publikováno v:
PLoS Pathogens, Vol 10, Iss 10, p e1004463 (2014)
Endosomal sorting complex required for transport (ESCRT) machinery supports the efficient budding of Marburg virus (MARV) and many other enveloped viruses. Interaction between components of the ESCRT machinery and viral proteins is predominantly medi
Externí odkaz:
https://doaj.org/article/d43c2906e6fb482f98c357f0a8784b15
Autor:
Tanmay A M Bharat, James D Riches, Larissa Kolesnikova, Sonja Welsch, Verena Krähling, Norman Davey, Marie-Laure Parsy, Stephan Becker, John A G Briggs
Publikováno v:
PLoS Biology, Vol 9, Iss 11, p e1001196 (2011)
Several major human pathogens, including the filoviruses, paramyxoviruses, and rhabdoviruses, package their single-stranded RNA genomes within helical nucleocapsids, which bud through the plasma membrane of the infected cell to release enveloped viri
Externí odkaz:
https://doaj.org/article/add284b5168b49b7a8f0d8b2547f688e
Publikováno v:
PLoS Pathogens, Vol 7, Iss 9, p e1002226 (2011)
Direct cell-cell spread of Human Immunodeficiency Virus type-1 (HIV-1) at the virological synapse (VS) is an efficient mode of dissemination between CD4(+) T cells but the mechanisms by which HIV-1 proteins are directed towards intercellular contacts
Externí odkaz:
https://doaj.org/article/077248f9c06745e6a0cabe8d9b9f4d07
Autor:
Sonja Welsch, Larissa Kolesnikova, Verena Krähling, James D Riches, Stephan Becker, John A G Briggs
Publikováno v:
PLoS Pathogens, Vol 6, Iss 4, p e1000875 (2010)
The filoviruses, Marburg and Ebola, are non-segmented negative-strand RNA viruses causing severe hemorrhagic fever with high mortality rates in humans and nonhuman primates. The sequence of events that leads to release of filovirus particles from cel
Externí odkaz:
https://doaj.org/article/23365fcaa7544805b42cefc54604f872