Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Sonja Vermeren"'
Autor:
Utsa Karmakar, Julia Y. Chu, Kruthika Sundaram, Anne L. Astier, Hannah Garside, Carsten G. Hansen, Ian Dransfield, Sonja Vermeren
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-13 (2021)
Abstract Persistent neutrophilic inflammation drives host damage in autoimmune diseases that are characterized by abundant immune complexes. Insoluble immune complexes (iICs) potently activate pro-inflammatory neutrophil effector functions. We and ot
Externí odkaz:
https://doaj.org/article/b1787cc0631143feb3407852a0bf8d83
Autor:
Waywen Loh, Sonja Vermeren
Publikováno v:
Cells, Vol 11, Iss 24, p 4076 (2022)
Neutrophils are highly abundant circulating leukocytes that are amongst the first cells to be recruited to sites of infection or sterile injury. Their ability to generate and release powerful cytotoxic products ties with their role in host defence fr
Externí odkaz:
https://doaj.org/article/95a4576f41714b6e99d22448449d4fd7
Autor:
Irina Balazs, Angela Horvath, Bettina Leber, Nicole Feldbacher, Wolfgang Sattler, Florian Rainer, Günter Fauler, Sonja Vermeren, Vanessa Stadlbauer
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 2, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/7d32d581398042c48e11959929b6af0f
Autor:
Nicole D. Barth, Ramon Subiros-Funosas, Lorena Mendive-Tapia, Rodger Duffin, Mario A. Shields, Jennifer A. Cartwright, Sónia Troeira Henriques, Jesus Sot, Felix M. Goñi, Rodolfo Lavilla, John A. Marwick, Sonja Vermeren, Adriano G. Rossi, Mikala Egeblad, Ian Dransfield, Marc Vendrell
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Programmed cell death or apoptosis is an essential biological process that is impaired in some diseases and can be used to assess the effectiveness of drugs. Here the authors design Apo-15 as a fluorogenic peptide for the detection and real-time imag
Externí odkaz:
https://doaj.org/article/7e4b972f90a04057803fb05db7c472e8
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/9cab24fb2d45457ca407c240f50f6a0c
Autor:
Melina Michael, Barry McCormick, Karen E. Anderson, Utsa Karmakar, Matthieu Vermeren, Stéphane Schurmans, Augustin Amour, Sonja Vermeren
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Neutrophils, the most abundant circulating leukocytes in humans have key roles in host defense and in the inflammatory response. Agonist-activated phosphoinositide 3-kinases (PI3Ks) are important regulators of many facets of neutrophil biology. PIP3
Externí odkaz:
https://doaj.org/article/305b1d79709942fd9a9faaf72e14e6d7
Autor:
Justin Killick, Joanne Hay, Elena Morandi, Sonja Vermeren, Saniya Kari, Thibault Angles, Anna Williams, Jan Damoiseaux, Anne L. Astier
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS), in which T-cell migration into the CNS is key for pathogenesis. Patients with MS exhibit impaired regulatory T cell populations, and both Foxp3+ Tregs and
Externí odkaz:
https://doaj.org/article/751aecc714fa45b3a0a1fb1bd1001f26
Publikováno v:
Cell Reports, Vol 17, Iss 2, Pp 374-386 (2016)
Neutrophils are peripheral blood leukocytes that represent the first line of immune cell defense against bacterial and fungal infections but are also crucial players in the generation of the inflammatory response. Many neutrophil cell surface recepto
Externí odkaz:
https://doaj.org/article/82d67d764e3645259443a11ab17d6ae9
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e116107 (2014)
ARAP3 is a GTPase-activating protein (GAP) that inactivates Arf6 and RhoA small GTPases. ARAP3 deficiency in mice causes a sprouting angiogenic defect resulting in embryonic lethality by E11. Mice with an ARAP3 R302,303A mutation (Arap3KI/KI) that pr
Externí odkaz:
https://doaj.org/article/f57c8c1baf5e43fd967d9478f503d2ff
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27385 (2011)
Angiogenesis is the generation of mature vascular networks from pre-existing vessels. Angiogenesis is crucial during the organism' development, for wound healing and for the female reproductive cycle. Several murine experimental systems are well suit
Externí odkaz:
https://doaj.org/article/712e3f46dac54c8698e06dde76b10117