Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Sonja Thaler"'
Autor:
Cristina L. Cotarelo, Arno Schad, Marcus Schmidt, Arnd Hönig, Jonathan P. Sleeman, Sonja Thaler
Publikováno v:
Cancers, Vol 15, Iss 6, p 1860 (2023)
Oncogene-induced senescence is thought to constitute a barrier to carcinogenesis by arresting cells at risk of malignant transformation. However, numerous findings suggest that senescent cells may conversely promote tumor growth and metastatic progre
Externí odkaz:
https://doaj.org/article/35493606ad794e72beef9a0522f2bdd1
Autor:
Claudia Koch, Andra Kuske, Simon A Joosse, Gökhan Yigit, George Sflomos, Sonja Thaler, Daniel J Smit, Stefan Werner, Kerstin Borgmann, Sebastian Gärtner, Parinaz Mossahebi Mohammadi, Laura Battista, Laure Cayrefourcq, Janine Altmüller, Gabriela Salinas‐Riester, Kaamini Raithatha, Arne Zibat, Yvonne Goy, Leonie Ott, Kai Bartkowiak, Tuan Zea Tan, Qing Zhou, Michael R Speicher, Volkmar Müller, Tobias M Gorges, Manfred Jücker, Jean‐Paul Thiery, Cathrin Brisken, Sabine Riethdorf, Catherine Alix‐Panabières, Klaus Pantel
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 9, Pp n/a-n/a (2020)
Abstract Functional studies giving insight into the biology of circulating tumor cells (CTCs) remain scarce due to the low frequency of CTCs and lack of appropriate models. Here, we describe the characterization of a novel CTC‐derived breast cancer
Externí odkaz:
https://doaj.org/article/6fcb45740e9c4955a376a11179160a9e
Publikováno v:
Cells, Vol 10, Iss 11, p 2868 (2021)
Around 70% of breast cancers express the estrogen receptor alpha (ERα). This receptor is of central importance for breast cancer development and estrogen-dependent tumor growth. However, the molecular mechanisms that are responsible for the control
Externí odkaz:
https://doaj.org/article/e4f6ebe1ff594e199a4765aecaf02fdf
Autor:
Sven Roßwag, Cristina L. Cotarelo, Klaus Pantel, Sabine Riethdorf, Jonathan P. Sleeman, Marcus Schmidt, Sonja Thaler
Publikováno v:
Cancers, Vol 13, Iss 8, p 1810 (2021)
Mechanisms of acquired endocrine resistance and late recurrence in patients with ER+/HER2− breast cancer are complex and not fully understood. Here, we evaluated mechanisms of acquired resistance in circulating tumor cells (CTCs) from an ER+/HER2
Externí odkaz:
https://doaj.org/article/2338aca974ce40e4a34418e0380c03c6
Publikováno v:
Cancers, Vol 12, Iss 9, p 2689 (2020)
The estrogen receptor alpha (ERα) is expressed by the majority of breast cancers and plays an important role in breast cancer development and tumor outgrowth. Although ERα is well known to be a specific and efficient therapeutic target, the molecul
Externí odkaz:
https://doaj.org/article/b253eb1fcdb445d3b05a1aa18ef3d1d5
Autor:
Martin Schuler, Matthias Theobald, Christoph Huber, Edite Antunes, Sonja Thaler, Patricia S. Hähnel
Supplementary Figure Legends 1-5 from Targeting AKT Signaling Sensitizes Cancer to Cellular Immunotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8504b85e8c8eb889f6037e21885558fb
https://doi.org/10.1158/0008-5472.22370118.v1
https://doi.org/10.1158/0008-5472.22370118.v1
Autor:
Martin Schuler, Matthias Theobald, Christoph Huber, Edite Antunes, Sonja Thaler, Patricia S. Hähnel
Supplementary Figure 2 from Targeting AKT Signaling Sensitizes Cancer to Cellular Immunotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c92cc738055fc9a6d40eb3325f0897e
https://doi.org/10.1158/0008-5472.22370130
https://doi.org/10.1158/0008-5472.22370130
Supplementary Figure Legend from RASSF1A Mediates p21Cip1/Waf1-Dependent Cell Cycle Arrest and Senescence through Modulation of the Raf-MEK-ERK Pathway and Inhibition of Akt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7394cebc70120c13def9a9c1264042da
https://doi.org/10.1158/0008-5472.22380089
https://doi.org/10.1158/0008-5472.22380089
Promoter hypermethylation preventing expression of the RAS association domain family 1 isoform A (RASSF1A) gene product is among the most abundant epigenetic deregulations in human cancer. Restoration of RASSF1A inhibits tumor cell growth in vitro an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22530883afd8e4ffea758209820b4d24
https://doi.org/10.1158/0008-5472.c.6499445
https://doi.org/10.1158/0008-5472.c.6499445
Autor:
Martin Schuler, Matthias Theobald, Christoph Huber, Edite Antunes, Sonja Thaler, Patricia S. Hähnel
Supplementary Figure 5 from Targeting AKT Signaling Sensitizes Cancer to Cellular Immunotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4963dd4d10da79c35de10c1b45467568
https://doi.org/10.1158/0008-5472.22370121
https://doi.org/10.1158/0008-5472.22370121