Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sonja Scholz"'
Autor:
Esther Yoon, Sarah Ahmed, Ryan Li, Sara Bandres-Ciga, Cornelis Blauwendraat, Irene Dustin, Sonja Scholz, Mark Hallett, Debra Ehrlich
Publikováno v:
BMC Neurology, Vol 23, Iss 1, Pp 1-6 (2023)
Abstract Background Deep brain stimulation (DBS) is a well-established treatment option for select patients with Parkinson’s Disease (PD). However, response to DBS varies, therefore, the ability to predict who will have better outcomes can aid pati
Externí odkaz:
https://doaj.org/article/57a6aa8d89fe42aeaa690c5f30bb56b5
Autor:
Michael A Nalls, Javier Simon-Sanchez, J Raphael Gibbs, Coro Paisan-Ruiz, Jose Tomas Bras, Toshiko Tanaka, Mar Matarin, Sonja Scholz, Charles Weitz, Tamara B Harris, Luigi Ferrucci, John Hardy, Andrew B Singleton
Publikováno v:
PLoS Genetics, Vol 5, Iss 3, p e1000415 (2009)
This research investigates the influence of demographic factors on human genetic sub-structure. In our discovery cohort, we show significant demographic trends for decreasing autozygosity associated with population variation in chronological age. Aut
Externí odkaz:
https://doaj.org/article/f0509b98fc484dd9880240b36d4ff384
Autor:
David Melzer, John R B Perry, Dena Hernandez, Anna-Maria Corsi, Kara Stevens, Ian Rafferty, Fulvio Lauretani, Anna Murray, J Raphael Gibbs, Giuseppe Paolisso, Sajjad Rafiq, Javier Simon-Sanchez, Hana Lango, Sonja Scholz, Michael N Weedon, Sampath Arepalli, Neil Rice, Nicole Washecka, Alison Hurst, Angela Britton, William Henley, Joyce van de Leemput, Rongling Li, Anne B Newman, Greg Tranah, Tamara Harris, Vijay Panicker, Colin Dayan, Amanda Bennett, Mark I McCarthy, Aimo Ruokonen, Marjo-Riitta Jarvelin, Jack Guralnik, Stefania Bandinelli, Timothy M Frayling, Andrew Singleton, Luigi Ferrucci
Publikováno v:
PLoS Genetics, Vol 4, Iss 5, p e1000072 (2008)
There is considerable evidence that human genetic variation influences gene expression. Genome-wide studies have revealed that mRNA levels are associated with genetic variation in or close to the gene coding for those mRNA transcripts - cis effects,
Externí odkaz:
https://doaj.org/article/d2f227e9bb3c4268be2aa96b26a335ee
Autor:
Joyce van de Leemput, Jayanth Chandran, Melanie A Knight, Lynne A Holtzclaw, Sonja Scholz, Mark R Cookson, Henry Houlden, Katrina Gwinn-Hardy, Hon-Chung Fung, Xian Lin, Dena Hernandez, Javier Simon-Sanchez, Nick W Wood, Paola Giunti, Ian Rafferty, John Hardy, Elsdon Storey, R J McKinlay Gardner, Susan M Forrest, Elizabeth M C Fisher, James T Russell, Huaibin Cai, Andrew B Singleton
Publikováno v:
PLoS Genetics, Vol 3, Iss 6, p e108 (2007)
We observed a severe autosomal recessive movement disorder in mice used within our laboratory. We pursued a series of experiments to define the genetic lesion underlying this disorder and to identify a cognate disease in humans with mutation at the s
Externí odkaz:
https://doaj.org/article/c07c3fcc18404aefa53f46f3f49c9ec0
Autor:
Jon B, Toledo, Carla, Abdelnour, Rimona S, Weil, Daniel, Ferreira, Federico, Rodriguez-Porcel, Andrea, Pilotto, Kathryn A, Wyman-Chick, Michel J, Grothe, Joseph P M, Kane, Angela, Taylor, Arvid, Rongve, Sonja, Scholz, James B, Leverenz, Bradley F, Boeve, Dag, Aarsland, Ian G, McKeith, Simon, Lewis, Iracema, Leroi, John P, Taylor
Publikováno v:
Alzheimer's & Dementia. 19:318-332
Dementia with Lewy bodies (DLB) is clinically defined by the presence of visual hallucinations, fluctuations, rapid eye movement (REM) sleep behavioral disorder, and parkinsonism. Neuropathologically, it is characterized by the presence of Lewy patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bda907cb2c742b928f22be2abf7648a9
https://doi.org/10.1002/alz.12814
https://doi.org/10.1002/alz.12814
Autor:
Patrick May, Sonja Scholz
Background and ObjectivesIsolated/idiopathic REM sleep behavior disorder (iRBD) and Lewy body dementia (LBD) are synucleinopathies that have partial genetic overlap with Parkinson’s disease (PD). Previous studies have shown that neuroinflammation p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::531376fe326e8f0a0f132cbf7b838aa1
https://doi.org/10.1101/2023.01.31.23284682
https://doi.org/10.1101/2023.01.31.23284682
Autor:
Adam Michael Phillippy, Sonja Scholz
Long-read sequencing technologies substantially overcome the limitations of short-reads but to date have not been considered as feasible replacement at scale due to a combination of being too expensive, not scalable enough, or too error-prone. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc906478f171392ec0fa4e064ab40c09
https://doi.org/10.1101/2023.01.12.523790
https://doi.org/10.1101/2023.01.12.523790
Autor:
Caroline Warly Solsberg, Sara Bandrés Ciga, Hampton Leonard, Sonja Scholz, Mary Makarious, Julie Lake
Parkinson’s disease (PD) has a large heritable component and genome-wide association studies to date have identified over 90 variants associated with PD, providing deeper insights into the disease biology. However, there have not been large-scale r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50b0e9a656684fe2cf011ea46bad4505
https://doi.org/10.1101/2022.11.08.22280168
https://doi.org/10.1101/2022.11.08.22280168
Publikováno v:
Movement disorders : official journal of the Movement Disorder Society. 37(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56483fe913b5bd965596663d81f1e0db
https://pubmed.ncbi.nlm.nih.gov/36026530
https://pubmed.ncbi.nlm.nih.gov/36026530
Autor:
Romy Baguhl, Sonja Scholz, Roald Papke, Axel Kramer, Ulrike Seifert, Claus-Dieter Heidecke, Harald Below, S. Diedrich, Ojan Assadian
Publikováno v:
Surgical Infections. 21:293-298
Aim: Since the introduction of surgical gloves, one of the main challenges has been to improve donning and wearability. For the wearer, the formation of “glove juice” is problematic. To improve gli...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea202d903f1d1d05451eff791b80ecd1
https://doi.org/10.1089/sur.2019.098
https://doi.org/10.1089/sur.2019.098