Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sonja Schlicht"'
Autor:
Felix C. Weber, Claas A. Meyer, Martin Ebeling, Per-Ola Freskgard, Antonio Iglesias, Michael Reth, Peter Bruenker, Thomas Singer, Sonja Schlicht, Daniel Breustedt, Jens Niewoehner
Publikováno v:
Pharmaceutical Research
Purpose Administration of therapeutic monoclonal antibodies (mAbs) is frequently accompanied by severe first infusion reactions (FIR). The mechanism driving FIR is still unclear. This study aimed to investigate the cellular and molecular mechanisms c
Autor:
Juliana Bessa, Claas A. Meyer, Antonio Iglesias, Maria Cristina De Vera Mudry, Javier Cote-Sierra, Sonja Schlicht, Susan H. Smith
Publikováno v:
Journal of Autoimmunity. 55:33-41
Non-resolving inflammation is a major contributor to chronic disease pathogenesis, including that of cancer, chronic obstructive pulmonary disease, asthma, arthritis, inflammatory bowel disease, multiple sclerosis and obesity. Some cytokines, such as
Autor:
Sonja Schlicht, Björn Boll, Sabine Boeckle, Anna Kiialainen, Martin Ebeling, Thomas Singer, Hermann Beck, Thomas Buckel, Thomas Weiser, Antonius G. Rolink, Atanas Koulov, Antonio Iglesias, Juliana Bessa
Publikováno v:
Pharmaceutical research. 32(7)
Protein aggregates have been discussed as a potential risk factor related to immunogenicity. Here we developed a novel human IgG transgenic (tg) mouse system expressing a mini-repertoire of human IgG1 antibodies (Abs) for the assessment of immunogeni