Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sonja Riesenhuber"'
Autor:
Martina Gaggl, Alexandra Repitz, Sonja Riesenhuber, Christof Aigner, Christopher Sliber, Melanie Fraunschiel, Daniel Cejka, Gere Sunder-Plassmann
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background: Sodium bicarbonate supplementation is a mainstay in the treatment of metabolic acidosis in patients with chronic kidney disease (CKD). Recent studies showed reduction of progression of CKD and reduced all-cause mortality. However, additio
Externí odkaz:
https://doaj.org/article/67cd7da8f89d4b3c8488d2039e4472ae
Protein binding of clindamycin in vivo by means of intravascular microdialysis in healthy volunteers
Autor:
Elizaveta Kurdina, Valentin Al Jalali, Markus Zeitlinger, Peter Matzneller, Matthias G. Vossen, Christoph Dorn, Sebastian G. Wicha, Sonja Riesenhuber, Stephan F Carrion Carrera, Beatrix Wulkersdorfer, Edith Lackner
Publikováno v:
The Journal of antimicrobial chemotherapy. 76(8)
Objectives The efficacy of an anti-infective drug is influenced by its protein binding (PB), since only the free fraction is active. We hypothesized that PB may vary in vitro and in vivo, and used clindamycin, a drug with high and concentration-depen