Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sonja Ploetz"'
Autor:
Florian Krach, Judith Stemick, Tom Boerstler, Alexander Weiss, Ioannis Lingos, Stephanie Reischl, Holger Meixner, Sonja Ploetz, Michaela Farrell, Ute Hehr, Zacharias Kohl, Beate Winner, Juergen Winkler
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Krach et al. dissect the molecular mechanism of the alternative splicing modulator Branaplam in Huntington’s disease. They show that the drug lowers mutant HTT protein levels and ameliorates alternative splicing pathology in an iPSC disease model.
Externí odkaz:
https://doaj.org/article/de498125578b4e53ac4080e1dc3242e6
Autor:
Sebastien Couillard-Despres, Rudolf Finkl, Beate Winner, Sonja Ploetz, Dirk Wiedermann, Robert Aigner, Ulrich Bogdahn, Juergen Winkler, Mathias Hoehn, Ludwig Aigner
Publikováno v:
Molecular Imaging, Vol 7 (2008)
Adult neurogenesis is a highly dynamic process modulated by several pathologic and environmental factors, as well as by various compounds. So far, available techniques to study neurogenesis are lengthy and personnel and cost intensive. We developed a
Externí odkaz:
https://doaj.org/article/a399ffc39a61467b995389cc97162b98
Autor:
Martin Regensburger, Mandy Krumbiegel, Steffen Uebe, Sonja Ploetz, Anita Rauch, Udo Trautmann, Arif B. Ekici, Frank Edenhofer, Katharina Günther, Annika Sommer, Beate Winner, Bernt Popp, Cornelia Kraus, Zacharias Kohl, André Reis, Michaela Farrell, Janina Grosch, Jürgen Winkler, Reza Asadollahi
Publikováno v:
Scientific reports
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Genetic integrity of induced pluripotent stem cells (iPSCs) is essential for their validity as disease models and for potential therapeutic use. We describe the comprehensive analysis in the ForIPS consortium: an iPSC collection from donors with neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a1174c087161ef3c0f9230fa525275
http://gala.gre.ac.uk/id/eprint/36707/1/36707_ASADOLLAHI_Need_for_high_resolution.pdf
http://gala.gre.ac.uk/id/eprint/36707/1/36707_ASADOLLAHI_Need_for_high_resolution.pdf
Autor:
Steffen Uebe, Cornelia Kraus, Arif B. Ekici, Beate Winner, Katharina Günther, Michaela Farrell, André Reis, Sonja Ploetz, Janina Grosch, Bernt Popp, J. Winkler, Zacharias Kohl, Martin Regensburger, Anita Rauch, Reza Asadollahi, Udo Trautmann, Mandy Krumbiegel, Frank Edenhofer, Annika Sommer
Genetic integrity of induced pluripotent stem cells (iPSCs) is essential for their validity as disease models and for potential therapeutic use. We describe the comprehensive analysis in the ForIPS consortium: an iPSC collection from donors with neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48792d209918b9a905eaf693e7924ee6
https://doi.org/10.1101/379818
https://doi.org/10.1101/379818
Autor:
Alexandra Karl, Jürgen Winkler, Robert Aigner, Jochen Klucken, Jörn Laemke, Eliezer Masliah, Beate Winner, Sonja Ploetz, Ludwig Aigner, Christian Hagl, Paula Desplats, Erich Buerger
Publikováno v:
Experimental Neurology. 219:543-552
Cell proliferation of neural progenitors in the subventricular zone (SVZ) of Parkinson disease (PD) patients and animal models is decreased. It was previously demonstrated that the neurotransmitter dopamine modulates cell proliferation in the embryon
Autor:
J. Marienhagen, Andreas Hehr, G. Uyanik, Joachim Weis, Ulrich Bogdahn, Haluk Topaloglu, Daniela Lenz, Josep Gamez, Bernhard H. F. Weber, Olaf Riess, Peter Bauer, Beate Winner, Thomas M. Ringer, Ute Hehr, Michael Bonin, Juergen Winkler, Akguen Olmez, Ludger Schöls, Anna Engel, Sonja Ploetz, Wolfgang Koehler, Gerhard Schuierer, Arndt Rolfs, Andrea Seibel, Rebecca Schüle
Publikováno v:
Annals of Neurology. 62:656-665
Objective: Hereditary spastic paraplegias (HSPs) comprise a heterogeneous group of neurodegenerative disorders resulting in progressive spasticity of the lower limbs. One form of autosomal recessive hereditary spastic paraplegia (ARHSP) with thin cor
Autor:
Norbert Weidner, G. Uyanik, Frank-Peter Wachs, Johanna Kaesbauer, Sonja Ploetz, Juergen Winkler, Clive N. Svendsen, Ludwig Aigner, Maurice Vroemen, Daniel Wilhelm, Jochen Klucken, Maren Engelhardt, Johanna Tebbing, Hans-Georg Kuhn, Sebastien Couillard-Despres, Claudia Karl
Publikováno v:
Laboratory Investigation. 83:949-962
Neural stem cells (NSCs) from the adult central nervous system are currently being investigated for their potential use in autologous cell replacement strategies. High expansion rates of NSCs in culture are crucial for the generation of a sufficient
Publikováno v:
Neuropediatrics. 31:195-198
Isolated Lissencephaly Sequence (ILS) and Double-Cortex Syndrome (DC) are neuronal heterotopias caused by developmental defects in neuronal precursor cell migration. We report on the clinical and genetic assessment of a German pedigree with DCIILS. A
Autor:
Dirk Wiedermann, Sebastien Couillard-Despres, Rudolf Finkl, Mathias Hoehn, Sonja Ploetz, Juergen Winkler, Beate Winner, Ulrich Bogdahn, Ludwig Aigner, Robert Aigner
Publikováno v:
Molecular Imaging, Vol 7 (2008)
Adult neurogenesis is a highly dynamic process modulated by several pathologic and environmental factors, as well as by various compounds. So far, available techniques to study neurogenesis are lengthy and personnel and cost intensive. We developed a
Autor:
Sebastien Couillard-Despres, Massimiliano Caioni, Ulrich Bogdahn, Francisco J. Rivera, Xiomara Pedré, Ludwig Aigner, Carlos Lois, Sonja Ploetz
Publikováno v:
BASE-Bielefeld Academic Search Engine
Adult stem cells reside in different tissues and organs of the adult organism. Among these cells are MSCs that are located in the adult bone marrow and NSCs that exist in the adult central nervous system (CNS). In transplantation experiments, MSCs de