Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sonja Moos"'
Autor:
Christina Lückel, Felix Picard, Hartmann Raifer, Lucia Campos Carrascosa, Anna Guralnik, Yajuan Zhang, Matthias Klein, Stefan Bittner, Falk Steffen, Sonja Moos, Federico Marini, Renee Gloury, Florian C. Kurschus, Ying-Yin Chao, Wilhelm Bertrams, Veronika Sexl, Bernd Schmeck, Lynn Bonetti, Melanie Grusdat, Michael Lohoff, Christina E. Zielinski, Frauke Zipp, Axel Kallies, Dirk Brenner, Michael Berger, Tobias Bopp, Björn Tackenberg, Magdalena Huber
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Dimethyl fumarate (DMF) is a therapy for multiple sclerosis (MS) with undetermined mechanism of action. Here the authors find that clinical response to DMF associates with decrease in IL-17-producing CD8+ T cells (Tc17), delineate molecular pathways
Externí odkaz:
https://doaj.org/article/2e2f0c2356834c5db881aabfe09b997c
Autor:
Katharina Bitschar, Birgit Sauer, Jule Focken, Hanna Dehmer, Sonja Moos, Martin Konnerth, Nadine A. Schilling, Stephanie Grond, Hubert Kalbacher, Florian C. Kurschus, Friedrich Götz, Bernhard Krismer, Andreas Peschel, Birgit Schittek
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Lugdunin is a peptide antibiotic produced by the skin commensal Staphylococcus lugdunensis. Here, the authors show that lugdunin reduces Staphylococcus aureus colonization in human keratinocytes and mouse skin by inducing the expression of human LL-3
Externí odkaz:
https://doaj.org/article/cdeeef7531844cd4aa56780138aa628c
Autor:
Florian Wanke, Sonja Moos, Andrew L. Croxford, André P. Heinen, Stephanie Gräf, Bettina Kalt, Denise Tischner, Juan Zhang, Isabelle Christen, Julia Bruttger, Nir Yogev, Yilang Tang, Morad Zayoud, Nicole Israel, Khalad Karram, Sonja Reißig, Sonja M. Lacher, Christian Reichhold, Ilgiz A. Mufazalov, Avraham Ben-Nun, Tanja Kuhlmann, Nina Wettschureck, Andreas W. Sailer, Klaus Rajewsky, Stefano Casola, Ari Waisman, Florian C. Kurschus
Publikováno v:
Cell Reports, Vol 18, Iss 5, Pp 1270-1284 (2017)
Arrival of encephalitogenic T cells at inflammatory foci represents a critical step in development of experimental autoimmune encephalomyelitis (EAE), the animal model for multiple sclerosis. EBI2 and its ligand, 7α,25-OHC, direct immune cell locali
Externí odkaz:
https://doaj.org/article/4430b96b5b16407db24119db388b3fa8
Autor:
Isabel Seeland, Ying Xiong, Christian Orlik, Daniel Deibel, Sandra Prokosch, Günter Küblbeck, Beate Jahraus, Daniela De Stefano, Sonja Moos, Florian C Kurschus, Bernd Arnold, Yvonne Samstag
Publikováno v:
PLoS Biology, Vol 16, Iss 7, p e2005380 (2018)
Cofilin is an essential actin remodeling protein promoting depolymerization and severing of actin filaments. To address the relevance of cofilin for the development and function of T cells in vivo, we generated knock-in mice in which T-cell-specific
Externí odkaz:
https://doaj.org/article/215b2d2a6d6c4815a62fab95592f1a5a
Autor:
Sonja Moos, Tommy Regen, Florian Wanke, Yizhu Tian, Lucas T. Arendholz, Judith Hauptmann, André P. Heinen, Lisa Bleul, Katharina Bier, Khalifa El Malki, Christoph Reinhardt, Immo Prinz, Andreas Diefenbach, Christiane Wolz, Birgit Schittek, Ari Waisman, Florian C. Kurschus
Publikováno v:
Journal of Investigative Dermatology.
Autor:
Felix Simon Ruben Picard, Veronika Lutz, Anna Brichkina, Felix Neuhaus, Teresa Ruckenbrod, Anna Hupfer, Hartmann Raifer, Matthias Klein, Tobias Bopp, Petra Ina Pfefferle, Rajkumar Savai, Immo Prinz, Ari Waisman, Sonja Moos, Hyun-Dong Chang, Stefan Heinrich, Detlef K Bartsch, Malte Buchholz, Shiv Singh, Mengyu Tu, Lukas Klein, Christian Bauer, Robert Liefke, Andreas Burchert, Ho-Ryun Chung, Philipp Mayer, Thomas M Gress, Matthias Lauth, Matthias Gaida, Magdalena Huber
Publikováno v:
Gut. :gutjnl-2022
ObjectivePancreatic ductal adenocarcinoma (PDAC) is characterised by an abundant desmoplastic stroma composed of cancer-associated fibroblasts (CAF) and interspersed immune cells. A non-canonical CD8+T-cell subpopulation producing IL-17A (Tc17) promo
Autor:
Florian C. Kurschus, Tobias Bopp, Ingo Bechman, Ari Waisman, Harald Binder, Silvia Cardoso, Subhashini Bolisetty, Lisa Johann, Judith Hauptmann, Federico Marini, Elisa Colombo, Ilgiz A. Mufazalov, Markus Schwaninger, Miguel P. Soares, Judith Strauß, Sonja Moos, Anupam Agarwal, Fred Lühder, Matthias Klein, Maja Kitic, Florian Wanke, Khalad Karram, Martin Krueger, Tommy Regen
Publikováno v:
Acta Neuropathologica
The proinflammatory cytokine interleukin 1 (IL-1) is crucially involved in the pathogenesis of multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE). Herein, we studied the role of IL-1 signaling in blood–brai
Autor:
Peter Vangheluwe, Jialin Chen, Verena Wüllner, Ann-Kathrin Herrmann, Jonas Graf, Sonja Moos, Florian C. Kurschus, Axel Methner, Philipp Albrecht, Bernd C. Kieseier
Publikováno v:
Free Radical Biology and Medicine. 141:338-347
Dimethyl fumarate (DMF) is widely used to treat the human autoimmune diseases multiple sclerosis (MS) and psoriasis. DMF causes short-term oxidative stress and activates the antioxidant response via the transcription factor Nrf2 but its immunosuppres
Publikováno v:
Journal of Investigative Dermatology. 139:1110-1117
The pathology of psoriasis strongly depends on IL-17A. Monoclonal antibodies blocking either the cytokine or its receptor are among the most efficient treatments for psoriatic patients. Keratinocytes can be activated upon exposure to IL-17A and tumor