Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sonja Mertins"'
Autor:
Alexander Klimka, Sonja Mertins, Anne Kristin Nicolai, Liza Marie Rummler, Paul G. Higgins, Saskia Diana Günther, Bettina Tosetti, Oleg Krut, Martin Krönke
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract Staphylococcus aureus represents a serious infectious threat to global public health and a vaccine against S. aureus represents an unmet medical need. We here characterise two S. aureus vaccine candidates, coproporphyrinogen III oxidase (Cgo
Externí odkaz:
https://doaj.org/article/e431207387584fa2afd867fea5da2aca
Autor:
Sonja Mertins, Paul G. Higgins, Caroline Thunissen, Henri Magein, Quentin Gilleman, Pascal Mertens, María González Rodríguez, Liza Marie Maus, Harald Seifert, Martin Krönke, Alexander Klimka
Publikováno v:
Journal of Medical Microbiology. 72
Introduction. Acinetobacter baumannii infections can be extremely challenging to treat owing to the worldwide prevalence of multidrug-resistant isolates, especially against carbapenems. Colonization with carbapenem-resistant A. baumannii (CRAb) requi
Autor:
Alexander Klimka, Paul G. Higgins, María González Rodríguez, Pascal Mertens, Céline Borlon, Harald Seifert, Quentin Gilleman, Sonja Mertins, Martin Krönke
Publikováno v:
Journal of Medical Microbiology. 68:1021-1032
Introduction. The spread of carbapenem-resistant Acinetobacter baumannii has led to a worldwide healthcare problem. Carbapenem resistance in A. baumannii is mainly mediated by the acquisition of the carbapenem-hydrolyzing oxacillinase OXA-23. The phe
Publikováno v:
Avian Diseases. 57:116-122
Campylobacter jejuni, a gram-negative motile bacterium commonly found in the chicken gastrointestinal tract, is one of the leading causes of bacterial gastroenteritis in humans worldwide. An intact and functional flagellum is important for C. jejuni
Publikováno v:
Microbiology. 154:3856-3876
PrfA is the major transcriptional activator of most virulence genes of Listeria monocytogenes. Its activity is modulated by a variety of culture conditions. Here, we studied the PrfA activity in the L. monocytogenes wild-type strain EGD and an isogen
Autor:
Sonja Mertins, Regina Ecke, Biju Joseph, Werner Goebel, Gerald Seidel, Mareen Sprehe, Monika Goetz, Wolfgang Hillen, Stefanie Müller-Altrock
Publikováno v:
Journal of Bacteriology. 189:473-490
Analysis ofListeria monocytogenes ptsH,hprK, andccpAmutants defective in carbon catabolite repression (CCR) control revealed significant alterations in the expression of PrfA-dependent genes. ThehprKmutant showed high up-regulation of PrfA-dependent
Autor:
Heather L. Wilson, Volker Gerdts, Siew Hon Ng, Rachelle M. Buchanan, J. Alex Pasternak, George Mutwiri, Sonja Mertins
Publikováno v:
BMC Veterinary Research
Background We previously determined that newborn piglets orally gavaged with Ovalbumin (OVA) responded to systemic OVA re-exposure with tolerance; if adjuvants were included in oral vaccine, piglets responded with antibody-mediated immunity (Vet Immu
Autor:
Mareen Sprehe, Norman Mauder, Stefanie Müller-Altrock, Wolfgang Hillen, Regina Ecke, Sonja Mertins, Daniela I. M. Loeffler, Werner Goebel, Gerald Seidel
Publikováno v:
Journal of Bacteriology. 188:7941-7956
PrfA, the master regulator of LIPI-1, is indispensable for the pathogenesis of the human pathogen Listeria monocytogenes and the animal pathogen Listeria ivanovii . PrfA is also present in the apathogenic species Listeria seeligeri , and in this stud
Publikováno v:
Journal of Bacteriology. 188:3887-3901
Listeria monocytogenesstrains expressing high levels of the virulence regulator PrfA (mutant PrfA* or wild-type PrfA) show strong growth inhibition in minimal media when they are supplemented with glucose but not when they are supplemented with gluco
Autor:
Regina Stoll, Adelbert Bacher, Eva Eylert, Sonja Mertins, Wolfgang Eisenreich, Werner Goebel, Jennifer Schär
Publikováno v:
Molecular microbiology. 69(4)
The intracellular metabolism of Listeria monocytogenes was studied by (13)C-isotopologue profiling using murine J774A.1 macrophages as host cells. Six hours after infection, bacteria were separated from the macrophages and hydrolyzed. Amino acids wer