Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Sonja M Kessler"'
Autor:
Sonja M Kessler, Bettina Leber, Jessica Hoppstädter, Nicole Golob-Schwarzl, Eva M Hofer, Christina S Schultheiss, Hans-Jörg Mischinger, Bernadette Liegl-Atzwanger, Carolin Lackner, Philipp Stiegler, Johannes Haybaeck
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0214756 (2019)
Background & aimPrimary hepatic angiosarcoma is a rare tumor with poor prognosis. The aim of this study was to generate a new angiosarcoma model to improve research on hepatic angiosarcoma.MethodsPigs sus scrofa were treated with different regimens o
Externí odkaz:
https://doaj.org/article/31e8a2d31fa44c51a4b667d816187d02
Autor:
Sonja M Kessler, Stephan Laggai, Elien Van Wonterghem, Katja Gemperlein, Rolf Müller, Johannes Haybaeck, Roosmarijn E. Vandenbroucke, Manfred Ogris, Claude Libert, Alexandra Kathrin Kiemer
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
Externí odkaz:
https://doaj.org/article/613cb79fbeb04a7eaa13250fcec72d09
Autor:
Sonja M Kessler, Stephan eLaggai, Elien evan Wonterghem, Katja eGemperlein, Rolf eMüller, Johannes eHaybaeck, Roosmarijn E Vandenbroucke, Manfred eOgris, Claude eLibert, Alexandra K Kiemer
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
Although insulin-like growth factor 2 (IGF2) has been reported to be overexpressed in steatosis and steatohepatitis, a causal role of IGF2 in steatosis development remains elusive. Aim of our study was to decipher the role of IGF2 in steatosis develo
Externí odkaz:
https://doaj.org/article/ebe9f798b3584fe5a8a53adbcd4e7fd2
Autor:
Vera H I Fengler, Tanja Macheiner, Sonja M Kessler, Beate Czepukojc, Katja Gemperlein, Rolf Müller, Alexandra K Kiemer, Christoph Magnes, Johannes Haybaeck, Carolin Lackner, Karine Sargsyan
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155163 (2016)
Although non-alcoholic and alcoholic fatty liver disease have been intensively studied, concerning pathophysiological mechanisms are still incompletely understood. This may be due to the use of different animal models and resulting model-associated v
Externí odkaz:
https://doaj.org/article/c01733df64fb40cea1c6182e40bb0915
Autor:
Miriam Krumbein, Froma Oberman, Yuval Cinnamon, Mordechai Golomb, Dalit May, Gilad Vainer, Vitali Belzer, Karen Meir, Irina Fridman, Johannes Haybaeck, Gerhard Poelzl, Izhak Kehat, Ronen Beeri, Sonja M. Kessler, Joel K. Yisraeli
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract The IGF2BP family of RNA binding proteins consists of three paralogs that regulate intracellular RNA localization, RNA stability, and translational control. Although IGF2BP1 and 3 are oncofetal proteins, IGF2BP2 expression is maintained in m
Externí odkaz:
https://doaj.org/article/d88543a9bb2e446cb1e179d0e5dbafe2
Autor:
Shilpee Chanda, Konstantin Lepikhov, Charlotte Dahlem, Hanna S. Schymik, Jessica Hoppstädter, An-Kristin Geber, Konrad Wagner, Sonja M. Kessler, Martin Empting, Alexandra K. Kiemer
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 1, p 41 (2024)
Background: The RNA-binding protein IGF2BP2/IMP2/VICKZ2/p62 is an oncofetal protein that is overexpressed in several cancer entities. Employing IMP2 knockout colorectal cancer cells, we could show the important role of IMP2 in several hallmarks of ca
Externí odkaz:
https://doaj.org/article/89d6e122b66b49bd99ed274709c6606a
Autor:
Marcel H. Schulz, Nina Gasparoni, Karl Nordström, Gilles Gasparoni, Stephan Laggai, Xinyi Yang, Anupam Sinha, Peter Ebert, Maren Falk-Paulsen, Sarah Kinkley, Ho-Ryun Chung, Philip Rosenstiel, Jan G. Hengstler, Jörn Walter, Sonja M. Kessler, Alexandra K. Kiemer, Ranjan Kumar Maji, Beate Czepukojc, Michael Scherer, Sascha Tierling
Fatty liver disease or the buildup of fat in the liver, has been reported to affect the global population. This comes with an increased risk for the development of fibrosis, cirrhosis, and hepatocellular carcinoma. Yet, little is known about the effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6252f9941037ffbe0378d2b7b2f7ebc5
https://doi.org/10.21203/rs.3.rs-2711309/v1
https://doi.org/10.21203/rs.3.rs-2711309/v1
Autor:
Kemal Hüsnü Can Başer, Alexandra K. Kiemer, Alden S. Estep, Ozlem Akbal-Dagistan, Afife Mat, Zulfiye Gul, James J. Becnel, Burcu Sen-Utsukarci, Sonja M. Kessler, Nurhayat Tabanca, Esra Eroglu-Ozkan, Serpil Demirci-Kayiran, Hilal Bardakci, Mine Kürkçüoğlu
Publikováno v:
South African Journal of Botany. 141:306-312
Zika, dengue, and Yellow fever are transmitted primarily by Aedes aegypti mosquitoes. Investigations to find more natural but highly effective pesticidal agents against Ae. aegypti have increased in the last few years. Plant-based compounds have been
Autor:
Nikolai Köhler, Marcus Höring, Beate Czepukojc, Tim Daniel Rose, Christa Buechler, Tarek Kröhler, Johannes Haybaeck, Gerhard Liebisch, Josch K. Pauling, Sonja M. Kessler, Alexandra K. Kiemer
Massive accumulation of lipids is a characteristic of alcoholic liver disease. Excess of hepatic fat activates Kupffer cells (KCs), which affect disease progression. Yet, KCs contribute to the resolution and advancement of liver injury. Aim of the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c22011588228cc46fa0a234798dc6f
Autor:
Charlotte Dahlem, Ali Abuhaliema, Sonja M. Kessler, Tarek Kröhler, Ben G. E. Zoller, Shilpee Chanda, Yingwen Wu, Simon Both, Fabian Müller, Konstantin Lepikhov, Susanne H. Kirsch, Stephan Laggai, Rolf Müller, Martin Empting, Alexandra K. Kiemer
The RNA-binding protein IGF2BP2/IMP2/VICKZ2/p62 is overexpressed in several tumor entities, promotes tumorigenesis and tumor progression, and has been suggested to worsen the disease outcome. The aim of this study is to (I) validate IMP2 as a potenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a59c5d6d4dcec614f0f81a5158e7e3ca