Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Sonja M Best"'
Autor:
Shanna S. Leventhal, Thomas Bisom, Dean Clift, Deepashri Rao, Kimberly Meade-White, Carl Shaia, Justin Murray, Evan A. Mihalakakos, Troy Hinkley, Steven J. Reynolds, Sonja M. Best, Jesse H. Erasmus, Leo C. James, Heinz Feldmann, David W. Hawman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Crimean-Congo Hemorrhagic Fever Virus (CCHFV) is a negative-sense RNA virus spread by Hyalomma genus ticks across Europe, Asia, and Africa. CCHF disease begins as a non-specific febrile illness which may progress into a severe hemorrhagic di
Externí odkaz:
https://doaj.org/article/a6d956186c9942bda98b2bc1f3d16cfd
Autor:
Gayatri Subramanian, Adam Hage, Friederike Feldmann, Abhilash I. Chiramel, Kristin L. McNally, Gail L. Sturdevant, Paul A. Beare, Sonja M. Best
Publikováno v:
Viruses, Vol 16, Iss 9, p 1377 (2024)
The unprecedented research effort associated with the emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) included several extensive proteomic studies that identified host proteins that interact with individual viral gene produc
Externí odkaz:
https://doaj.org/article/b6f86d9456e7430c99d8646e2ca3fe4f
Autor:
Shelly J. Robertson, Olivia Bedard, Kristin L. McNally, Carl Shaia, Chad S. Clancy, Matthew Lewis, Rebecca M. Broeckel, Abhilash I. Chiramel, Jeffrey G. Shannon, Gail L. Sturdevant, Rebecca Rosenke, Sarah L. Anzick, Elvira Forte, Christoph Preuss, Candice N. Baker, Jeffrey M. Harder, Catherine Brunton, Steven Munger, Daniel P. Bruno, Justin B. Lack, Jacqueline M. Leung, Amirhossein Shamsaddini, Paul Gardina, Daniel E. Sturdevant, Jian Sun, Craig Martens, Steven M. Holland, Nadia A. Rosenthal, Sonja M. Best
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Inflammation in response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection drives severity of coronavirus disease 2019 (COVID-19) and is influenced by host genetics. To understand mechanisms of inflammation, animal mo
Externí odkaz:
https://doaj.org/article/4707d2cef54a462c9164528ec8d5861f
Publikováno v:
Viruses, Vol 16, Iss 7, p 997 (2024)
The evolutionary pressures exerted by viral infections have led to the development of various cellular proteins with potent antiviral activities, some of which are known as antiviral restriction factors. TRIpartite Motif-containing protein 5 alpha (T
Externí odkaz:
https://doaj.org/article/984f30febf0b4e30a98e0c1aabbbc04a
Autor:
Yongli Xiao, Paul A. Beare, Sonja M. Best, David M. Morens, Marshall E. Bloom, Jeffery K. Taubenberger
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Rocky Mountain spotted fever (RMSF) is a rapidly progressive and often fatal tick-borne disease caused by Rickettsia rickettsii. Its discovery and characterization by Howard Ricketts has been hailed as a remarkable historical example of dete
Externí odkaz:
https://doaj.org/article/7e4c405387b44c7f8416fe26a2682682
Publikováno v:
Pathogens, Vol 13, Iss 2, p 167 (2024)
Single-cell RNA sequencing has soared in popularity in recent years. The ability to deeply profile the states of individual cells during the course of disease or infection has helped to expand our knowledge of coordinated responses. However, signific
Externí odkaz:
https://doaj.org/article/5b877b4717a34e428dcc232105ab2f33
Autor:
Xueqiao Liu, Hong-Su Park, Yumiko Matsuoka, Celia Santos, Lijuan Yang, Cindy Luongo, Ian N Moore, Reed F Johnson, Nicole L Garza, Peng Zhang, Paolo Lusso, Sonja M Best, Ursula J Buchholz, Cyril Le Nouën
Publikováno v:
PLoS Pathogens, Vol 19, Iss 6, p e1011057 (2023)
The pediatric live-attenuated bovine/human parainfluenza virus type 3 (B/HPIV3)-vectored vaccine expressing the prefusion-stabilized SARS-CoV-2 spike (S) protein (B/HPIV3/S-2P) was previously evaluated in vitro and in hamsters. To improve its immunog
Externí odkaz:
https://doaj.org/article/eb32882f2f894b40aeab331f51b202e1
Autor:
Rosa C Coldbeck-Shackley, Ornella Romeo, Sarah Rosli, Linden J Gearing, Jodee A Gould, San S Lim, Kylie H Van der Hoek, Nicholas S Eyre, Byron Shue, Sarah A Robertson, Sonja M Best, Michelle D Tate, Paul J Hertzog, Michael R Beard
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1010843 (2023)
The immunological surveillance factors controlling vulnerability of the female reproductive tract (FRT) to sexually transmitted viral infections are not well understood. Interferon-epsilon (IFNɛ) is a distinct, immunoregulatory type-I IFN that is co
Externí odkaz:
https://doaj.org/article/5466e29dbea44bb9bb2a994a75c3a117
Autor:
Guoli Shi, Abhilash I. Chiramel, Tiansheng Li, Kin Kui Lai, Adam D. Kenney, Ashley Zani, Adrian C. Eddy, Saliha Majdoul, Lizhi Zhang, Tirhas Dempsey, Paul A. Beare, Swagata Kar, Jonathan W. Yewdell, Sonja M. Best, Jacob S. Yount, Alex A. Compton
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 24 (2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in immunocompromised individuals is associated with prolonged virus shedding and evolution of viral variants. Rapamycin and its analogs (rapalogs, including everolimus, temsirolim
Externí odkaz:
https://doaj.org/article/54c02ef4c7e14f2d8fd82a8b248817d9
Autor:
Luwanika Mlera, Danielle K. Offerdahl, David W. Dorward, Aaron Carmody, Abhilash I. Chiramel, Sonja M. Best, Marshall E. Bloom
Publikováno v:
Emerging Microbes and Infections, Vol 10, Iss 1, Pp 1378-1389 (2021)
The vector-borne flaviviruses (VBFVs) are well known for causing great misery and death in humans worldwide. The VBFVs include those transmitted by mosquitos, such as Zika virus (ZIKV), dengue virus; and those transmitted by ticks including the tick-
Externí odkaz:
https://doaj.org/article/d4d892f0a3a84e28937b0e437a4aabfb