Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sonja Kuschel"'
Autor:
John W. Ward, Malcolm A. Y. Gall, Sonja Kuschel, Daniel J. Tetlow, Matthew O. Kitching, Guillaume De Bo, David A. Leigh
Publikováno v:
Journal of the American Chemical Society, 2017, Vol.139(31), pp.10875-10879 [Peer Reviewed Journal]
De Bo, G, Gall, M, Kitching, M, Kuschel, S, Leigh, D, Tetlow, D & Ward, J 2017, ' Sequence-Specific Beta-Peptide Synthesis by a Rotaxane-Based Molecular Machine ', American Chemical Society. Journal . https://doi.org/10.1021/jacs.7b05850
De Bo, G, Gall, M, Kitching, M, Kuschel, S, Leigh, D, Tetlow, D & Ward, J 2017, ' Sequence-Specific Beta-Peptide Synthesis by a Rotaxane-Based Molecular Machine ', American Chemical Society. Journal . https://doi.org/10.1021/jacs.7b05850
We report on the synthesis and operation of a three-barrier, rotaxane-based, artificial molecular machine capable of sequence-specific beta-homo (β3) peptide synthesis. The machine utilizes non-proteinogenic β3-amino acids, a class of amino acids n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e5f0161018af06c4f0ac51afe3710a6
https://doi.org/10.1021/jacs.7b05850
https://doi.org/10.1021/jacs.7b05850
Autor:
Sonja Kuschel, David A. Leigh, Malcolm A. Y. Gall, Julien De Winter, Pascal Gerbaux, Guillaume De Bo
Publikováno v:
De Bo, G, Gall, M A Y, Kuschel, S, De Winter, J, Gerbaux, P & Leigh, D A 2018, ' An artificial molecular machine that builds an asymmetric catalyst ', Nature Nanotechnology, vol. 13, no. 5, pp. 381-385 . https://doi.org/10.1038/s41565-018-0105-3
Biomolecular machines perform types of complex molecular-level tasks that artificial molecular machines can aspire to. The ribosome, for example, translates information from the polymer track it traverses (messenger RNA) to the new polymer it constru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390a37989cfcfefa1a0b781b930ee0c1
https://doi.org/10.1038/s41565-018-0105-3
https://doi.org/10.1038/s41565-018-0105-3
Autor:
Marcus Papmeyer, Bartosz Lewandowski, John W. Ward, David A. Leigh, Guillaume De Bo, Sonja Kuschel
Publikováno v:
De Bo, G, Kuschel, S, Leigh, D A, Lewandowski, B, Papmeyer, M & Ward, J W 2014, ' Efficient assembly of threaded molecular machines for sequence-specific synthesis ', Journal of the American Chemical Society, vol. 136, no. 15, pp. 5811-5814 . https://doi.org/10.1021/ja5022415
We report on an improved strategy for the preparation of artificial molecular machines that can pick up and assemble reactive groups in sequence by traveling along a track. In the new approach a preformed rotaxane synthon is attached to the end of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d13981a86d6b198360625e17836d77
https://doi.org/10.1021/ja5022415
https://doi.org/10.1021/ja5022415
Autor:
Marcus Papmeyer, Guillaume De Bo, John W. Ward, Stephen M. Goldup, Sonja Kuschel, Antony E. Fernandes, Daniel M. D'Souza, Philipp M. E. Gramlich, Dominik Heckmann, Bartosz Lewandowski, David A. Leigh, María J. Aldegunde
Publikováno v:
Lewandowski, B, De Bo, G, Ward, J W, Papmeyer, M, Kuschel, S, Aldegunde, M J, Gramlich, P M E, Heckmann, D, Goldup, S M, D'Souza, D M, Fernandes, A E & Leigh, D A 2013, ' Sequence-specific peptide synthesis by an artificial small-molecule machine. ', Science (New York, NY), vol. 339, no. 6116, pp. 189-193 . https://doi.org/10.1126/science.1229753
Ribosomal Rotaxane? The ribosome is an extraordinarily sophisticated molecular machine, assembling amino acids into proteins based on the precise sequence dictated by messenger RNA. Lewandowski et al. (p. 189 ) have now taken a step toward the prepar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fac1f93a2e8d54a80a82627fd4e4e7db
https://doi.org/10.1126/science.1229753
https://doi.org/10.1126/science.1229753
Publikováno v:
Tetrahedron Letters. 53:1717-1719
This Letter concerns the investigation of a solid phase based method for no carrier-added nucleophilic [ 18 F]fluorination of aromatic compounds via de-diazofluorination. Initial screening of reaction conditions was conducted using soluble analogues,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47a8da6ace58ab92ab91a6a15291be8a
https://doi.org/10.1016/j.tetlet.2012.01.082
https://doi.org/10.1016/j.tetlet.2012.01.082
Publikováno v:
Bioconjugate chemistry. 22(3)
In this study, we investigated the use of poly-mer-bound precursor for generating a radiolabeled prosthetic group to be used for conjugate labeling of biological macromolecules. For the approach, a trialkyltin chloride in which the tin was bound to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67cae6596a522c4f0755e94c24c3b271
https://pubmed.ncbi.nlm.nih.gov/21309585
https://pubmed.ncbi.nlm.nih.gov/21309585