Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sonja Krösser"'
Autor:
Ahmad M. Fahmy, Jennifer S. Harthan, David G. Evans, Jack V. Greiner, Joseph Tauber, John D. Sheppard, Sonja Krösser, Jason L. Vittitow
Publikováno v:
Frontiers in Ophthalmology, Vol 4 (2024)
BackgroundDry eye disease (DED) is commonly caused by excessive tear film evaporation due to Meibomian gland dysfunction (MGD). There is a need for DED treatment options that address tear evaporation and benefit patients across a broad range of demog
Externí odkaz:
https://doaj.org/article/d4572072e7f04837aa628162d8099232
Publikováno v:
American Journal of Ophthalmology. 252:265-274
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 188:100-107
Publikováno v:
Ophthalmology.
To evaluate the efficacy and safety of NOV03 (perfluorohexyloctane) ophthalmic drop in patients with dry eye disease (DED) associated with meibomian gland dysfunction (MGD).Eight-week, phase 3, multicenter, randomized, double-masked, saline-controlle
Autor:
Esen K. Akpek, David L. Wirta, Johnathon E. Downing, Joseph Tauber, John D. Sheppard, Joseph B. Ciolino, Alice S. Meides, Sonja Krösser
Publikováno v:
JAMA Ophthalmology. 141:459
ImportanceDry eye disease (DED) is a common public health problem with significant impact on vision-related quality of life and well-being of patients. Medications with rapid onset of action and a good tolerability profile remain an unmet need.Object
Autor:
Lei Tian, Zuojun Gao, Lei Zhu, Xiaoru Shi, Shaozhen Zhao, Hao Gu, Guoxing Xu, Linnong Wang, Hong Dai, Hong Zhang, Xiuming Jin, Ke Ma, Yonggen Xu, Lixiao Ma, Cheng Pei, Bilian Ke, Sonja Krösser, Yunxia Zhang, Ying Jie
Publikováno v:
JAMA Ophthalmology. 141:385
ImportanceMeibomian gland dysfunction (MGD) is a leading cause of evaporative dry eye disease (DED). Medical and surgical management for DED is limited; therefore, new treatment options are sought.ObjectiveTo evaluate the efficacy and safety of SHR80
Publikováno v:
Cornea
Purpose: NOV03 has a unique dual mode of action to address dry eye disease (DED) associated with meibomian gland dysfunction. SEECASE evaluated the efficacy, safety, and tolerability of NOV03 at 2 dosing regimens compared with a saline comparator in
Topical semifluorinated alkane-based azithromycin suspension for the management of ocular infections
Autor:
Ilva D. Rupenthal, Simon Swift, Priyanka Agarwal, Kirsten Eickhoff, Jennifer P. Craig, Sonja Krösser
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 142:83-91
The management of ocular infections is challenging due to poor drug bioavailability and vehicle related adverse effects associated with current antibiotic eye drops. Semifluorinated alkanes (SFAs) are reportedly well-tolerated on the ocular surface a
Autor:
Dale W. Usner, Thomas Schlüter, George W Ousler, Joseph B. Ciolino, Blair E. Boehmer, Eugene B McLaurin, David Wirta, John D. Sheppard, Sonja Krösser, Meides Alice
Publikováno v:
Cornea
Dry eye disease (DED) is defined by the International Dry Eye Workshop (TFOS DEWS II) as a multifactorial disease of the ocular surface characterized by a loss of homeostasis of the tear film, and accompanied by ocular symptoms, in which tear film in
Autor:
Kathleen Kunert, Sonja Krösser, Johannes Menzel-Severing, Gerd Geerling, Philipp Steven, Elisabeth M. Messmer, Norbert Schrage, Florian T A Kretz, Albert J. Augustin, Michael Beckert, Wolfgang A. Schrems, Thomas Kaercher
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics
Purpose: Meibomian gland disease is generally accepted as the leading cause for evaporative dry eye disease (DED). In a previous study, perfluorohexyloctane, a semifluorinated alkane, has been demonstrated to significantly increase tear film breakup