Avian Bornaviruses Escape Recognition by the Innate Immune System

Autor: Antje Reuter, Andreas Ackermann, Sonja Kothlow, Monika Rinder, Bernd Kaspers, Peter Staeheli

Publikováno v: Viruses, Vol 2, Iss 4, Pp 927-938 (2010)

Like other pathogens that readily persist in animal hosts, members of the Bornaviridae family have evolved effective mechanisms to evade the innate immune response. The prototype of this virus family, Borna disease virus employs an unusual replicatio

Externí odkaz: https://doaj.org/article/dd283a2ac1b0415091a5e3b3cb8cc08e

Prolonged effect of BAFF on chicken B cell development revealed by RCAS retroviral gene transfer in vivo

Autor: Michael J. H. Ratcliffe, Bernd Kaspers, Katharina Schenk-Weibhauser, Sonja Kothlow

Publikováno v: Molecular Immunology. 47:1619-1628

Chickens provide an important model for developmental biology as well as phylogenetic studies of the immune system. In many species cytokines are important regulators of immune functions and recently we identified the chicken homologue of BAFF (B cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64000d01974236646418eaf98e08134
https://doi.org/10.1016/j.molimm.2010.01.011

CD40 ligand supports the long-term maintenance and differentiation of chicken B cells in culture

Autor: Bernd Kaspers, John R. Young, Sonja Kothlow, Iris Morgenroth, Clive A. Tregaskes

Publikováno v: Developmental & Comparative Immunology. 32:1015-1026

TNF family members play crucial roles in mammalian B-cell differentiation and function, many of which have not been demonstrated in other species. To investigate the avian CD40/CD40L system, a chicken CD40 cDNA, obtained by expression screening, was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0edb533cdc338617ea3d458bddadeaf
https://doi.org/10.1016/j.dci.2008.01.012

Mycoplasma synoviae lipoprotein MSPB, the N-terminal part of VlhA haemagglutinin, induces secretion of nitric oxide, IL-6 and IL-1β in chicken macrophages

Autor: Mojca Narat, Dušan Benčina, Sonja Kothlow, Miha Lavric, Bernd Kaspers

Publikováno v: Veterinary Microbiology. 121:278-287

Mycoplasma synoviae is a major pathogen of chickens and turkeys, causing respiratory disease and infectious synovitis. M. synoviae haemagglutinin VlhA is an abundant surface-exposed lipoprotein and immunodominant antigen. Post-translational cleavage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d74b230f3d37002cd84870019c0ec2
https://doi.org/10.1016/j.vetmic.2006.12.005

Acute paretic syndrome in juvenile White Leghorn chickens resembles late stages of acute inflammatory demyelinating polyneuropathies in humans

Autor: Sophie R. Bader, Sonja Kothlow, Kaspar Matiasek, Bernd Kaspers, Susanne C. N. Schwarz, Wolfgang W. Schmahl, Steffen Weigend, Ahmad Reza Sharifi, Sascha Trapp, Rudolf Preisinger, Hans-Christian Philipp

Publikováno v: Journal of Neuroinflammation
Journal of Neuroinflammation, BioMed Central, 2010, 7, pp.7. ⟨10.1186/1742-2094-7-7⟩
Journal of Neuroinflammation, Vol 7, Iss 1, p 7 (2010)
Journal of Neuroinflammation (7), 7. (2010)

BackgroundSudden limb paresis is a common problem in White Leghorn flocks, affecting about 1% of the chicken population before achievement of sexual maturity. Previously, a similar clinical syndrome has been reported as being caused by inflammatory d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca24f7012c23e34fe4dfe4be159bc6eb
https://doi.org/10.1186/1742-2094-7-7