Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Sonja Kallendrusch"'
Autor:
Anja Seckinger, Sara Majocchi, Valéry Moine, Lise Nouveau, Hoang Ngoc, Bruno Daubeuf, Ulla Ravn, Nicolas Pleche, Sebastien Calloud, Lucile Broyer, Laura Cons, Adeline Lesnier, Laurence Chatel, Anne Papaioannou, Susana Salgado-Pires, Sebastian Krämer, Ines Gockel, Florian Lordick, Krzysztof Masternak, Yves Poitevin, Giovanni Magistrelli, Pauline Malinge, Limin Shang, Sonja Kallendrusch, Klaus Strein, Dirk Hose
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-23 (2023)
Abstract Background T-cell retargeting to eliminate CEACAM5-expressing cancer cells via CEACAM5xCD3 bispecific antibodies (BsAbs) showed limited clinical activity so far, mostly due to insufficient T-cell activation, dose-limiting toxicities, and for
Externí odkaz:
https://doaj.org/article/30b29a2c343143119fd06970474edb47
Autor:
Changwu Wu, Siming Gong, Yingjuan Duan, Chao Deng, Sonja Kallendrusch, Laura Berninghausen, Georg Osterhoff, Nikolas Schopow
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-22 (2023)
Abstract Background The tumor microenvironment (TME) has a central role in the oncogenesis of osteosarcomas. The composition of the TME is essential for the interaction between tumor and immune cells. The aim of this study was to establish a prognost
Externí odkaz:
https://doaj.org/article/9453d0d9a13743d693443cb5287e04ed
Autor:
David Junk, Sebastian Krämer, Johannes Broschewitz, Hennig Laura, Chiara Massa, Yousef Moulla, Ngoc Anh Hoang, Astrid Monecke, Uwe Eichfeld, Ingo Bechmann, Florian Lordick, Barbara Seliger, Sonja Kallendrusch
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Despite novel immunotherapies being approved and established for the treatment of non-small cell lung cancer (NSCLC), ex vivo models predicting individual patients’ responses to immunotherapies are missing. Especially immune modulating the
Externí odkaz:
https://doaj.org/article/93c3f2ef09034aa991047266a691170c
Autor:
Siming Gong, Changwu Wu, Franziska Köhler, Jürgen Meixensberger, Nikolas Schopow, Sonja Kallendrusch
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Lower-grade glioma (LGG) is a group of tumors arising from the cells of the central nervous system. Although various therapy interventions are used, the prognosis remains different. Novel biomarkers are needed for the prognosis of disease and novel t
Externí odkaz:
https://doaj.org/article/f1135ba052db4e97b7e959f668039179
Autor:
Ina Patties, Sonja Kallendrusch, Lisa Böhme, Eva Kendzia, Henry Oppermann, Frank Gaunitz, Rolf-Dieter Kortmann, Annegret Glasow
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-16 (2019)
Abstract Background Glioblastoma is the most common and aggressive brain tumour in adults with a median overall survival of only 14 months after standard therapy with radiation therapy (IR) and temozolomide (TMZ). In a novel multimodal treatment appr
Externí odkaz:
https://doaj.org/article/3e5fedde859f4e2caead25268b769921
Publikováno v:
Genes, Vol 13, Iss 5, p 787 (2022)
Despite various treatment attempts, the heterogenous group of soft tissue sarcomata (STS) with more than 100 subtypes still shows poor outcomes. Therefore, effective biomarkers for prognosis prediction and personalized treatment are of high importanc
Externí odkaz:
https://doaj.org/article/c45b29a53d5043a09c650111dfe17763
Autor:
Marlon Hußtegge, Ngoc Anh Hoang, Jakob Rebstock, Astrid Monecke, Ines Gockel, Arved Weimann, Guido Schumacher, Ingo Bechmann, Florian Lordick, Sonja Kallendrusch, Justus Körfer
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Emerging immunotherapies quest for better patient stratification in cancer treatment decisions. Moderate response rates of PD-1 inhibition in gastric and esophagogastric junction cancers urge for meaningful human model systems that allow for investig
Externí odkaz:
https://doaj.org/article/c3b19dbf19ac44c8bd1dbe30434846cd
Publikováno v:
Cancers, Vol 14, Iss 2, p 448 (2022)
Soft tissue sarcomas (STS) are a rare disease with high recurrence rates and poor prognosis. Missing therapy options together with the high heterogeneity of this tumor type gives impetus to the development of individualized treatment approaches. This
Externí odkaz:
https://doaj.org/article/09312edd8b3c43409f8af0a1b6df7234
Autor:
Nikolas Schopow, Sonja Kallendrusch, Siming Gong, Felicitas Rapp, Justus Körfer, Martin Gericke, Nick Spindler, Christoph Josten, Stefan Langer, Ingo Bechmann
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233152 (2020)
Obesity is associated with significantly higher mortality rates, and excess adipose tissue is involved in respective pathologies. Here we established a human adipose tissue slice cultures (HATSC) model ex vivo. HATSC match the in vivo cell compositio
Externí odkaz:
https://doaj.org/article/5b483f91be29459ebbd4dea19bf28e54
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9903 (2021)
The overexpression of the enzymes involved in the degradation of procollagen lysine is correlated with various tumor entities. Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (PLOD3) expression was found to be correlated to the progression and mig
Externí odkaz:
https://doaj.org/article/45f111cf76bf428bb61efcd3d3af4949