Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Sonja I. Gringhuis"'
Autor:
Melissa Stunnenberg, Joris K. Sprokholt, John L. van Hamme, Tanja M. Kaptein, Esther M. Zijlstra-Willems, Sonja I. Gringhuis, Teunis B. H. Geijtenbeek
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Strong innate and adaptive immune responses are paramount in combating viral infections. Dendritic cells (DCs) detect viral infections via cytosolic RIG-I like receptors (RLRs) RIG-I and MDA5 leading to MAVS-induced immunity. The DEAD-box RNA helicas
Externí odkaz:
https://doaj.org/article/fd20377470564fb0a29ea1ba5bcc16a1
Autor:
Melissa Stunnenberg, Lisa van Pul, Joris K. Sprokholt, Karel A. van Dort, Sonja I. Gringhuis, Teunis B. H. Geijtenbeek, Neeltje A. Kootstra
Publikováno v:
Viruses, Vol 12, Iss 7, p 764 (2020)
The mitochondrial antiviral protein MAVS is a key player in the induction of antiviral responses; however, human immunodeficiency virus 1 (HIV-1) is able to suppress these responses. Two linked single nucleotide polymorphisms (SNPs) in the MAVS gene
Externí odkaz:
https://doaj.org/article/5e0729a89e67458e89bd07ae1f7bb3a6
Autor:
Sonja I. Gringhuis, Tanja M. Kaptein, Ester B. M. Remmerswaal, Agata Drewniak, Brigitte A. Wevers, Bart Theelen, Geert R. A. M. D’Haens, Teun Boekhout, Teunis B. H. Geijtenbeek
Publikováno v:
Nature Immunology, 23(12), 1735-1748. Nature Publishing Group
Nature immunology, 23(12), 1735-1748. Nature Publishing Group
Nature immunology, 23(12), 1735-1748. Nature Publishing Group
The non-pathogenic TH17 subset of helper T cells clears fungal infections, whereas pathogenic TH17 cells cause inflammation and tissue damage; however, the mechanisms controlling these distinct responses remain unclear. Here we found that fungi sensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb95b9e0a1be7f25f872ff5b9849bad7
https://pure.knaw.nl/portal/en/publications/02768b71-10f2-4c54-9daa-117c4aec0199
https://pure.knaw.nl/portal/en/publications/02768b71-10f2-4c54-9daa-117c4aec0199
Autor:
Melissa, Stunnenberg, John L, van Hamme, Esther M, Zijlstra-Willems, Sonja I, Gringhuis, Teunis B H, Geijtenbeek
Publikováno v:
Journal of Leukocyte Biology. FASEB
Pathogens trigger multiple pattern recognition receptors (PRRs) that together dictate innate and adaptive immune responses. Understanding the crosstalk between PRRs is important to enhance vaccine efficacy. Abortive HIV-1 RNA transcripts are produced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f7c079a899e687aa41e8dd0e66d705
https://research.vumc.nl/en/publications/91b770e8-a60d-4b79-b582-4a940cd42736
https://research.vumc.nl/en/publications/91b770e8-a60d-4b79-b582-4a940cd42736
Autor:
Sonja I, Gringhuis, Tanja M, Kaptein, Ester B M, Remmerswaal, Agata, Drewniak, Brigitte A, Wevers, Bart, Theelen, Geert R A M, D'Haens, Teun, Boekhout, Teunis B H, Geijtenbeek
Publikováno v:
Nature immunology.
The non-pathogenic T
Autor:
Sonja I. Gringhuis, Joris K. Sprokholt, Melissa Stunnenberg, Neeltje A. Kootstra, Karel A. van Dort, Lisa van Pul, Teunis B. H. Geijtenbeek
Publikováno v:
Viruses, 12(7):764. Multidisciplinary Digital Publishing Institute (MDPI)
Viruses, Vol 12, Iss 764, p 764 (2020)
Viruses
Volume 12
Issue 7
Viruses, Vol 12, Iss 764, p 764 (2020)
Viruses
Volume 12
Issue 7
The mitochondrial antiviral protein MAVS is a key player in the induction of antiviral responses
however, human immunodeficiency virus 1 (HIV-1) is able to suppress these responses. Two linked single nucleotide polymorphisms (SNPs) in the MAVS g
however, human immunodeficiency virus 1 (HIV-1) is able to suppress these responses. Two linked single nucleotide polymorphisms (SNPs) in the MAVS g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f892081448d77b918cfc0d8505b33f1
https://pure.amc.nl/en/publications/mavs-genetic-variation-is-associated-with-decreased-hiv1-replication-in-vitro-and-reduced-cd4-t-cell-infection-in-hiv1infected-individuals(ece10630-def1-4553-a969-c5a883ae197f).html
https://pure.amc.nl/en/publications/mavs-genetic-variation-is-associated-with-decreased-hiv1-replication-in-vitro-and-reduced-cd4-t-cell-infection-in-hiv1infected-individuals(ece10630-def1-4553-a969-c5a883ae197f).html
Autor:
Joris K. Sprokholt, Teunis B. H. Geijtenbeek, Esther M. Zijlstra-Willems, John L. van Hamme, Melissa Stunnenberg, Tanja M. Kaptein, Sonja I. Gringhuis
Publikováno v:
Frontiers in Immunology
Frontiers in immunology, 11:8. Frontiers Media S.A.
Frontiers in Immunology, Vol 11 (2020)
Frontiers in immunology, 11:8. Frontiers Media S.A.
Frontiers in Immunology, Vol 11 (2020)
Strong innate and adaptive immune responses are paramount in combating viral infections. Dendritic cells (DCs) detect viral infections via cytosolic RIG-I like receptors (RLRs) RIG-I and MDA5 leading to MAVS-induced immunity. The DEAD-box RNA helicas
Autor:
Joppe W R Hovius, Marein A W P de Jong, Jeroen den Dunnen, Manja Litjens, Erol Fikrig, Tom van der Poll, Sonja I Gringhuis, Teunis B H Geijtenbeek
Publikováno v:
PLoS Pathogens, Vol 4, Iss 2, p e31 (2008)
Ixodes ticks are major vectors for human pathogens, such as Borrelia burgdorferi, the causative agent of Lyme disease. Tick saliva contains immunosuppressive molecules that facilitate tick feeding and B. burgdorferi infection. We here demonstrate, to
Externí odkaz:
https://doaj.org/article/fc03abd8a9664cb38d2c90db72a5cb93
Publikováno v:
Cytokine & growth factor reviews, 40, 32-39. Elsevier BV
Cytokine & Growth Factor Reviews
Cytokine & Growth Factor Reviews
HIV-1 sensors and their signaling features have been an ongoing topic of intense research over the last decade, as these mechanisms fail to establish protective immunity against HIV-1. Here, we discuss how HIV-1 infects dendritic cells (DCs) and whic
Autor:
Kim van Noort, Lotte B. Westerhof, Jaap Bakker, Nicole N. Driessen, Maria Yazdanbakhsh, Bart Everts, Ruud H. P. Wilbers, Geert Smant, Aska Goverse, Sonja I. Gringhuis, Cornelis H. Hokke, Hermelijn H. Smits, Arjen Schots, Katja Obieglo, Gabriele Schramm
Publikováno v:
Scientific reports, 7. Nature Publishing Group
Scientific Reports, 7
Scientific Reports
Scientific Reports 7 (2017)
Scientific Reports, 7
Scientific Reports
Scientific Reports 7 (2017)
Helminth parasites control host-immune responses by secreting immunomodulatory glycoproteins. Clinical trials and mouse model studies have demonstrated the potential of helminth-derived glycoproteins for the treatment of immune-related diseases, like