Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sonja E. Gustin"'
Autor:
Emanuele Pelosi, Patrick S. Western, Dagmar Wilhelm, Andrew H. Sinclair, Raphael H. Rastetter, Kirsten Hogg, Denise C. Miles, Sonja E. Gustin, Jessica M Stringer
Publikováno v:
Developmental Biology. 412:250-260
Sexual development is initiated through differentiation of testicular Sertoli cells or ovarian granulosa cells. Although these supporting cells are considered to develop from common bipotential precursors, recent evidence suggests that distinct suppo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a0f44e6a27518641a0d14f80570a0b
https://doi.org/10.1016/j.ydbio.2016.02.024
https://doi.org/10.1016/j.ydbio.2016.02.024
Publikováno v:
Reproduction (Cambridge, England). 152(5)
Testis development is dependent on the key sex-determining factors SRY and SOX9, which activate the essential ligand FGF9. Although FGF9 plays a central role in testis development, it is unable to induce testis formation on its own. However, other gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6b041357bd2ecf6418527d3f5949bc5
https://pubmed.ncbi.nlm.nih.gov/27495231
https://pubmed.ncbi.nlm.nih.gov/27495231
Autor:
Patrick S. Western, Sonja E. Gustin, Sarah J Meachem, Amanda J. Notini, Andrew H. Sinclair, Peter Koopman, Vincent R. Harley, J.A. van den Bergen, Peter J. McClive
Publikováno v:
Sexual Development. 6:223-230
In an effort to identify novel candidate genes involved in testis determination, we previously used suppression subtraction hybridisation PCR on male and female whole embryonic (12.0–12.5 days post coitum) mouse gonads. One gene to emerge from our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cb475ef53ccde4bbab99c03cdff92c8
https://doi.org/10.1159/000339723
https://doi.org/10.1159/000339723
Publikováno v:
The Journal of Immunology. 177:5980-5989
c-Cbl and Cbl-b E3 ubiquitin ligases are abundantly expressed in hemopoietic cells where they negatively regulate the activity and levels of many cell surface receptors and associated signaling molecules. By comparing bone marrow-derived mast cells f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::912ea1b48b2eb63b06bfe9d38b2f5194
https://doi.org/10.4049/jimmunol.177.9.5980
https://doi.org/10.4049/jimmunol.177.9.5980
Autor:
Joachim R. Göthert, Berthold Göttgens, Uli Schmidt, Stephen M. Jane, Mark A. Hall, C. Glenn Begley, Anthony R. Green, J. Anke M. van Eekelen, David J. Izon, Sonja E. Gustin
Publikováno v:
Blood. 104:1769-1777
Tumor growth is dependent in part on “neoangiogenesis.” Functional involvement of bone marrow (BM)-derived cells in this process has been demonstrated. However, it remains controversial as to whether tumor endothelium itself is BM derived. Here w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd328f83ff4fa1bbac72c2f925353bf
https://doi.org/10.1182/blood-2003-11-3952
https://doi.org/10.1182/blood-2003-11-3952
Autor:
Sonja E. Gustin, Jane E. Olsen, David L. Ollis, Ian G. Young, James M. Murphy, P.D. Jeffrey, Sally C. Ford
Publikováno v:
Journal of Biological Chemistry. 279:26500-26508
Interleukin-3 (IL-3) is a cytokine produced by activated T-cells and mast cells that is active on a broad range of hematopoietic cells and in the nervous system and appears to be important in several chronic inflammatory diseases. In this study, alan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4c66cbb2a6e157605d3d255906dba7e
https://doi.org/10.1074/jbc.m402705200
https://doi.org/10.1074/jbc.m402705200
Autor:
David A. Mann, Sally C. Ford, Paul D. Carr, Ian G. Young, David L. Ollis, Sonja E. Gustin, Alice P. Church
Publikováno v:
European Journal of Biochemistry. 268:2905-2911
The major signalling entity of the receptors for the haemopoietic cytokines granulocyte-macrophage colony stimulating factor (GM-CSF), interleukin-3 (IL-3) and interleukin-5 (IL-5) is the shared βc receptor, which is activated by ligand-specific α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cd628ffa354ea2fafe455aa1fd815aa
https://doi.org/10.1046/j.1432-1327.2001.02178.x
https://doi.org/10.1046/j.1432-1327.2001.02178.x
Autor:
David L. Ollis, Paul D. Carr, Ian Walker, Alice P. Church, David A. Mann, Donna Woltring, Ian G. Young, James M. Murphy, Sonja E. Gustin, Sally C. Ford
Publikováno v:
Cell. 104(2):291-300
The receptor systems for the hemopoietic cytokines GM-CSF, IL-3, and IL-5 consist of ligand-specific alpha receptor subunits that play an essential role in the activation of the shared betac subunit, the major signaling entity. Here, we report the st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d9cd68675471c3367bb18d1554bf72
Autor:
Sally C. Ford, Ian G. Young, Lyndall J. Briggs, David A. Jans, Patricia Jans, Sonja E. Gustin
Publikováno v:
FEBS Letters. 406:315-320
Interleukin (IL)-5 is central in regulating eosinophilia in allergic disease and parasitic infections. We have identified a bipartite nuclear localisation signal (NLS) within amino acids 95–111 of human IL-5 (hIL-5), also present in mouse IL-5 (mIL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba35888f692d3bff9ad085a48c94fdf
https://doi.org/10.1016/s0014-5793(97)00293-7
https://doi.org/10.1016/s0014-5793(97)00293-7
Autor:
Patrick S. Western, Vincent R. Harley, Sonja E. Gustin, Peter Koopman, Peter J. McClive, Andrew H. Sinclair
Publikováno v:
Endocrinology. 149(12)
Ethanolamine kinase 2 (Eki2) was previously isolated from a differential expression screen designed to identify candidate genes involved in testis development and differentiation. In mouse, Eki2 is specifically up-regulated in Sertoli cells of the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15dc3865009a5efa3eac7e83c24728bb
https://pubmed.ncbi.nlm.nih.gov/18755794
https://pubmed.ncbi.nlm.nih.gov/18755794