Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Sonja C. Schriever"'
Autor:
Seun Akindehin, Arkadiusz Liskiewicz, Daniela Liskiewicz, Miriam Bernecker, Cristina Garcia-Caceres, Daniel J. Drucker, Brian Finan, Gerald Grandl, Robert Gutgesell, Susanna M. Hofmann, Ahmed Khalil, Xue Liu, Perla Cota, Mostafa Bakhti, Oliver Czarnecki, Aimée Bastidas-Ponce, Heiko Lickert, Lingru Kang, Gandhari Maity, Aaron Novikoff, Sebastian Parlee, Ekta Pathak, Sonja C. Schriever, Michael Sterr, Siegfried Ussar, Qian Zhang, Richard DiMarchi, Matthias H. Tschöp, Paul T. Pfluger, Jonathan D. Douros, Timo D. Müller
Publikováno v:
Molecular Metabolism, Vol 83, Iss , Pp 101915- (2024)
Objective: The glucose-dependent insulinotropic polypeptide (GIP) decreases body weight via central GIP receptor (GIPR) signaling, but the underlying mechanisms remain largely unknown. Here, we assessed whether GIP regulates body weight and glucose c
Externí odkaz:
https://doaj.org/article/4df457ac59ce49e8af09680efdd590e2
Autor:
Valentina S. Klaus, Sonja C. Schriever, José Manuel Monroy Kuhn, Andreas Peter, Martin Irmler, Janina Tokarz, Cornelia Prehn, Gabi Kastenmüller, Johannes Beckers, Jerzy Adamski, Alfred Königsrainer, Timo D. Müller, Martin Heni, Matthias H. Tschöp, Paul T. Pfluger, Dominik Lutter
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101295- (2021)
Objective: Technological advances have brought a steady increase in the availability of various types of omics data, from genomics to metabolomics. Integrating these multi-omics data is a chance and challenge for systems biology; yet, tools to fully
Externí odkaz:
https://doaj.org/article/d17775f6456844a1ba26907fd0446001
Autor:
Peter Baumann, Sonja C. Schriever, Stephanie Kullmann, Annemarie Zimprich, Andreas Peter, Valerie Gailus‐Durner, Helmut Fuchs, Martin Hrabe de Angelis, Wolfgang Wurst, Matthias H. Tschöp, Martin Heni, Sabine M. Hölter, Paul T. Pfluger
Publikováno v:
Brain and Behavior, Vol 11, Iss 1, Pp n/a-n/a (2021)
Abstract Background Dusp8 is the first GWAS‐identified gene that is predominantly expressed in the brain and has previously been linked with the development of diabetes type 2 in humans. In this study, we unravel how Dusp8 is involved in the regula
Externí odkaz:
https://doaj.org/article/f3346153e5b54e88bc62fe2207255e83
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Obesity and being overweight have become a worldwide epidemic affecting more than 1.9 billion adults and 340 million children. Efforts to curb this global health burden by developing effective long-term non-surgical weight loss interventions continue
Externí odkaz:
https://doaj.org/article/b0f708796eda4e198e96588cc7d354d5
Autor:
Katrin Pfuhlmann, Sonja C. Schriever, Beata Legutko, Peter Baumann, Luke Harrison, Dhiraj G. Kabra, Emily Violette Baumgart, Matthias H. Tschöp, Cristina Garcia-Caceres, Paul T. Pfluger
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-11 (2018)
Abstract ᅟ Astrocytosis is a reactive process involving cellular, molecular, and functional changes to facilitate neuronal survival, myelin preservation, blood brain barrier function and protective glial scar formation upon brain insult. The overal
Externí odkaz:
https://doaj.org/article/abbfdab518234e23897efe4b8a595c9a
Autor:
Dhiraj G. Kabra, Katrin Pfuhlmann, Cristina García-Cáceres, Sonja C. Schriever, Veronica Casquero García, Adam Fiseha Kebede, Esther Fuente-Martin, Chitrang Trivedi, Kristy Heppner, N. Henriette Uhlenhaut, Beata Legutko, Uma D. Kabra, Yuanqing Gao, Chun-Xia Yi, Carmelo Quarta, Christoffer Clemmensen, Brian Finan, Timo D. Müller, Carola W. Meyer, Marcelo Paez-Pereda, Kerstin Stemmer, Stephen C. Woods, Diego Perez-Tilve, Robert Schneider, Eric N. Olson, Matthias H. Tschöp, Paul T. Pfluger
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Histone deacetylases (HDACs) regulate energy metabolism in peripheral tissues, but whether HDACs expressed in the brain influence systemic metabolism is unknown. Here the authors show that hypothalamic HDAC5 expression is affected by the diet and HDA
Externí odkaz:
https://doaj.org/article/05d180e6a43443a4a0aaf1a16b919fe2
Autor:
Regina Ensenauer, Ralph Fingerhut, Sonja C. Schriever, Barbara Fink, Marc Becker, Nina C. Sellerer, Philipp Pagel, Andreas Kirschner, Torsten Dame, Bernhard Olgemöller, Wulf Röschinger, Adelbert A. Roscher
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 5, Pp 1012-1020 (2012)
Quantitative analysis of mitochondrial FA β-oxidation (FAO) has drawn increasing interest for defining lipid-induced metabolic dysfunctions, such as in obesity-induced insulin resistance, and evaluating pharmacologic strategies to improve β-oxidati
Externí odkaz:
https://doaj.org/article/d127472f521b4bbc9a5107b4d0905102
Autor:
Sonja C. Schriever, Paul T. Pfluger
Publikováno v:
Molecular Metabolism, Vol 4, Iss 5, Pp 363-364 (2015)
Externí odkaz:
https://doaj.org/article/abdafd85a6e84412a9c02376b1afa4f9
Autor:
Ismael González-García, Elena García-Clavé, Alberto Cebrian-Serrano, Ophélia Le Thuc, Raian E. Contreras, Yanjun Xu, Tim Gruber, Sonja C. Schriever, Beata Legutko, Jutta Lintelmann, Jerzy Adamski, Wolfgang Wurst, Timo D. Müller, Stephen C. Woods, Paul T. Pfluger, Matthias H. Tschöp, Alexandre Fisette, Cristina García-Cáceres
Publikováno v:
Cell metabolism 35(3), 438-455.e7 (2023). doi:10.1016/j.cmet.2023.02.004
Until menopause, women have a lower propensity to develop metabolic diseases than men, suggestive of a protective role for sex hormones. Although a functional synergy between central actions of estrogens and leptin has been demonstrated to protect ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea50ec13163a71892a9a6c287661c81
https://pub.dzne.de/record/256515
https://pub.dzne.de/record/256515
Light sheet fluorescence microscopy guided MALDI-imaging mass spectrometry of cleared tissue samples
Autor:
Kaspar Matiasek, Annette Feuchtinger, Achim Buck, Na Sun, Luke B. Harrison, Axel Walch, Jürgen Schlegel, Paul T. Pfluger, Zhihao Xu, David Wiles, Andreas Blutke, Thomas Kunzke, Sonja C. Schriever, Katharina Huber, Michaela Aichler, Stefanie M. Hauck
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Sci. Rep. 10:14461 (2020)
Scientific Reports
Sci. Rep. 10:14461 (2020)
Scientific Reports
Light sheet fluorescence microscopy (LSFM) of optically cleared biological samples represents a powerful tool to analyze the 3-dimensional morphology of tissues and organs. Multimodal combinations of LSFM with additional analyses of the identical sam