Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sonja C Bernhard"'
Autor:
Gabriele Pohlig, Sonja C Bernhard, Johannes Blum, Christian Burri, Alain Mpanya, Jean-Pierre Fina Lubaki, Alfred Mpoo Mpoto, Blaise Fungula Munungu, Patrick Mangoni N'tombe, Gratias Kambau Manesa Deo, Pierre Nsele Mutantu, Florent Mbo Kuikumbi, Alain Fukinsia Mintwo, Augustin Kayeye Munungi, Amadeu Dala, Stephen Macharia, Constantin Miaka Mia Bilenge, Victor Kande Betu Ku Mesu, Jose Ramon Franco, Ndinga Dieyi Dituvanga, Richard R Tidwell, Carol A Olson
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 2, p e0004363 (2016)
BACKGROUND:Sleeping sickness (human African trypanosomiasis [HAT]) is a neglected tropical disease with limited treatment options that currently require parenteral administration. In previous studies, orally administered pafuramidine was well tolerat
Externí odkaz:
https://doaj.org/article/54ad4e12d63a49d885737d44dd4774db
Autor:
Christian Burri, Patrick D Yeramian, James L Allen, Ada Merolle, Kazadi Kyanza Serge, Alain Mpanya, Pascal Lutumba, Victor Kande Betu Ku Mesu, Constantin Miaka Mia Bilenge, Jean-Pierre Fina Lubaki, Alfred Mpoo Mpoto, Mark Thompson, Blaise Fungula Munungu, Francisco Manuel, Théophilo Josenando, Sonja C Bernhard, Carol A Olson, Johannes Blum, Richard R Tidwell, Gabriele Pohlig
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 2, p e0004362 (2016)
BACKGROUND:Sleeping sickness (human African trypanosomiasis [HAT]) is caused by protozoan parasites and characterized by a chronic progressive course, which may last up to several years before death. We conducted two Phase 2 studies to determine the
Externí odkaz:
https://doaj.org/article/85fe4504afb44d6aa8d68789bbb6f651
Autor:
Bruno Scherrer, Victor Kande Betu Ku Mesu, Crispin Lumbala, Olaf Valverde Mordt, Nathalie Strub-Wourgaft, Wilfried Mutombo Kalonji, Séverine Blesson, Willy Kuziena, Jean Pierre Fina Lubaki, Steven Lumeya Vuvu, Pathou Nganzobo Ngima, Augustin Kasongo Bonama, François Simon, Lewis Kaninda Badibabi, Jean Louis Lumaliza Solomo, Medard Ilunga, Sonja C. Bernhard, Francis Regongbenga Dama, Josué Amici Heradi, Guylain Mandula, Papy Kavunga Lukula, Clélia Bardonneau, Hélène Mahenzi Mbembo, Digas Ngolo Tete, Sophie Delhomme, Antoine Tarral
Publikováno v:
The Lancet. 391:144-154
Summary Background Few therapeutic options are available to treat the late-stage of human African trypanosomiasis, a neglected tropical disease, caused by Trypanosoma brucei gambiense (g-HAT). The firstline treatment is a combination therapy of oral
Autor:
Jean Pierre Fina Lubaki, Blaise Fungula Munungu, Gabriele Pohlig, James L. Allen, Francisco Manuel, Victor Kande Betu Ku Mesu, Alain Mpanya, Théophilo Josenando, Johannes Blum, Alfred Mpoo Mpoto, Carol A. Olson, Mark E. Thompson, Sonja C. Bernhard, A Merolle, Christian Burri, Patrick Yeramian, Pascal Lutumba, Constantin Miaka Mia Bilenge, Richard R. Tidwell, Kazadi Kyanza Serge
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 2, p e0004362 (2016)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background Sleeping sickness (human African trypanosomiasis [HAT]) is caused by protozoan parasites and characterized by a chronic progressive course, which may last up to several years before death. We conducted two Phase 2 studies to determine the
Autor:
Christian Burri, Patrick Mangoni N’tombe, Richard R. Tidwell, Carol A. Olson, Pierre Nsele Mutantu, José R. Franco, Alain Fukinsia Mintwo, Johannes Blum, Amadeu Dala, Alfred Mpoo Mpoto, Constantin Miaka Mia Bilenge, Stephen Macharia, Augustin Kayeye Munungi, Gabriele Pohlig, Florent Mbo Kuikumbi, Alain Mpanya, Gratias Kambau Manesa Deo, Ndinga Dieyi Dituvanga, Sonja C. Bernhard, Victor Kande Betu Ku Mesu, Jean Pierre Fina Lubaki, Blaise Fungula Munungu
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 2, p e0004363 (2016)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background Sleeping sickness (human African trypanosomiasis [HAT]) is a neglected tropical disease with limited treatment options that currently require parenteral administration. In previous studies, orally administered pafuramidine was well tolerat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e60a4421a5baa6e621690fefdd5db0
Publikováno v:
International Journal for Parasitology. 37:1443-1448
Resistance to melarsoprol and pentamidine was induced in bloodstream-form Trypanosoma brucei rhodesiense STIB 900 in vitro, and drug sensitivity was determined for melarsoprol, pentamidine and furamidine. The resistant populations were also inoculate