Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sonja, Markwart"'
Supplementary Data from Inhibition of mTOR Radiosensitizes Soft Tissue Sarcoma and Tumor Vasculature
Autor:
Daniel A. Hamstra, Michael E. Ray, Sonja Markwart, Yash R. Somnay, Aaron C. Spalding, James D. Murphy
Supplementary Data from Inhibition of mTOR Radiosensitizes Soft Tissue Sarcoma and Tumor Vasculature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d985c4687ec84f3dc5aae94df1452d5
https://doi.org/10.1158/1078-0432.22440364
https://doi.org/10.1158/1078-0432.22440364
Autor:
Kathleen M. Woods Ignatoski, Navdeep K. Grewal, Sonja Markwart, Donna L. Livant, Stephen P. Ethier
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 5, Iss 2, Pp 128-134 (2003)
We have previously shown that human breast cancer cells that overexpress erbB-2 are growth factorindependent. In order to test the contribution of erbB2 to this and other transformed phenotypes without the genetic instability of cancer cells, erbB-2
Externí odkaz:
https://doaj.org/article/f6b5fa36f950403288dee93d2ebec07c
Autor:
Kevin S. Fay, Aaron C. Spalding, Donna L. Livant, Korrene F. Rockwood, Sonja Markwart, Evan D. Staszewski, Hongren Yao, Zhao-Zhu Zeng
Publikováno v:
Translational Oncology. 2:8-20
Angiogenesis requires endothelial cell invasion and is crucial for wound healing and for tumor growth and metastasis. Invasion of native collagen is mediated by the alpha(5)beta(1) integrin fibronectin receptor. Thus, alpha(5)beta(1) up-regulation on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c329fcba3a31620c1883e32cbc2b74c1
https://doi.org/10.1593/tlo.08187
https://doi.org/10.1593/tlo.08187
Autor:
James D. Murphy, Aaron C. Spalding, Michael E. Ray, Yash R. Somnay, Daniel A. Hamstra, Sonja Markwart
Publikováno v:
Clinical Cancer Research. 15:589-596
Purpose: The PI3K/Akt/mTOR prosurvival pathway is frequently up-regulated in soft tissue sarcoma. Mammalian target of rapamycin (mTOR) inhibitors, such as rapamycin, have recently shown clinical benefit in soft tissue sarcoma, and mTOR inhibition has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528c187bf5306a76d152262982268231
https://doi.org/10.1158/1078-0432.ccr-08-1019
https://doi.org/10.1158/1078-0432.ccr-08-1019
Autor:
Evan T. Keller, Arul M. Chinnaiyan, Kathleen M. Woods Ignatoski, Sonja Markwart, Adaikkalam Vellaichamy, Kam C. Yeung, Michael E. Ray, Navdeep K. Grewal
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 72:153-160
Purpose External beam radiotherapy (RT) is often used in an attempt to cure localized prostate cancer (PCa), but it is only palliative against disseminated disease. Raf kinase inhibitory protein (RKIP) is a metastasis suppressor whose expression is r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07fa1af59710148942a5d2fb48f4924b
https://doi.org/10.1016/j.ijrobp.2008.04.072
https://doi.org/10.1016/j.ijrobp.2008.04.072
Autor:
Kathleen M. Woods Ignatoski, Zhao-Zhu Zeng, Yifeng Jia, Donna L. Livant, Stephen P. Ethier, Korrene F. Rockwood, Sonja Markwart
Publikováno v:
Cancer Research. 64:8674-8681
Integrins contribute to progression in many cancers, including breast cancer. For example, the interaction of alpha(5)beta(1) with plasma fibronectin causes the constitutive invasiveness of human prostate cancer cells. Inhibition of this process redu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603cf588ccb7fb04728964505a482486
https://doi.org/10.1158/0008-5472.can-04-0069
https://doi.org/10.1158/0008-5472.can-04-0069
Autor:
Donna L. Livant, Kathleen M. Woods Ignatoski, Stephen P. Ethier, Navdeep K. Grewal, Sonja Markwart
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 5, Iss 2, Pp 128-134 (2003)
We have previously shown that human breast cancer cells that overexpress erbB-2 are growth factor-independent. In order to test the contribution of erbB-2 to this and other transformed phenotypes without the genetic instability of cancer cells, erbB-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64ab1638f39af7a893cb0cfe35f7019
Autor:
Donna L. Livant, Sonja Markwart, Mats Ljungman, Michelle T. Paulsen, Erica S. Dyer, Meidee Goh
Publikováno v:
International Journal of Cancer. 101:496-499
Histone deacetylase inhibitors, such as phenylbutyrate, are currently undergoing clinical trials as potential anticancer agents. Phenylbutyrate can induce cell differentiation and apoptosis in a number of cancer cell types and can act in synergy with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a44485364f9f97676370b6010f01f3f
https://doi.org/10.1002/ijc.10609
https://doi.org/10.1002/ijc.10609
Autor:
Ronald C. Haaseth, Philip C. Andrews, David L. Allen, Stephen P. Ethier, Donna L. Livant, Yanling Wu, Kotoku Kurachi, Sonja Markwart, R. Kaye Brabec
Publikováno v:
Journal of Clinical Investigation. 105:1537-1545
The PHSRN sequence of the plasma fibronectin (pFn) cell-binding domain induces human keratinocytes and fibroblasts to invade the naturally serum-free extracellular matrices of sea urchin embryos. The potency of acetylated, amidated PHSRN (Ac-PHSRN-NH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::873a34f18543860e64f7f545a7dea55a
https://doi.org/10.1172/jci8527
https://doi.org/10.1172/jci8527
Autor:
Kathleen M. Woods Ignatoski, Tomohiko Maehama, Donna L. Livant, Jack E. Dixon, Stephen P. Ethier, Sonja Markwart
Publikováno v:
British Journal of Cancer
Amplification and overexpression of ERBB-2 in human breast cancer is thought to play a significant role in the progression of the disease; however, its precise role in the aetiology of altered phenotypes associated with human breast cancer is unknown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa4a9f1e6b8e5738aad6b3d8856b76a7
http://europepmc.org/articles/PMC2363331
http://europepmc.org/articles/PMC2363331