Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Sonja, Johann"'
Publikováno v:
Cells, Vol 12, Iss 14, p 1836 (2023)
In mammals, the circadian system controls various physiological processes to maintain metabolism, behavior, and immune function during a daily 24 h cycle. Although driven by a cell-autonomous core clock in the hypothalamus, rhythmic activities are en
Externí odkaz:
https://doaj.org/article/6a2cefb4d88c4e95bf214b7f5c6ffd99
Autor:
Cordian Beyer, Joachim Weis, Anna Pösch, Sonja Johann, Eleonora Aronica, Carmen Hummel, Omid Leylamian
Publikováno v:
Neuroscience, 463, 288-302. Elsevier Limited
Inflammasomes are key components of the innate immune system and activation of these multiprotein platforms is a crucial event in the etiopathology of amyotrophic lateral sclerosis (ALS). Inflammasomes consist of a pattern recognition receptor (PRR),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a44fa19687302c137ac93ff37dc38f
https://pure.amc.nl/en/publications/expression-and-cell-typespecific-localization-of-inflammasome-sensors-in-the-spinal-cord-of-sod1g93a-mice-and-sporadic-amyotrophic-lateral-sclerosis-patients(81fbbfc5-09ce-4cc1-b13f-e01551fef92d).html
https://pure.amc.nl/en/publications/expression-and-cell-typespecific-localization-of-inflammasome-sensors-in-the-spinal-cord-of-sod1g93a-mice-and-sporadic-amyotrophic-lateral-sclerosis-patients(81fbbfc5-09ce-4cc1-b13f-e01551fef92d).html
Publikováno v:
Neuroscience. 472
G-protein-coupled-estrogen-receptor 1 (GPER1) is a membrane-bound receptor that mediates estrogen signaling via intracellular signaling cascades. We recently showed that GPER1 promotes the distal dendritic enrichment of hyperpolarization activated an
Akademický článek
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Autor:
Carmen, Hummel, Omid, Leylamian, Anna, Pösch, Joachim, Weis, Eleonora, Aronica, Cordian, Beyer, Sonja, Johann
Publikováno v:
Neuroscience. 463
Inflammasomes are key components of the innate immune system and activation of these multiprotein platforms is a crucial event in the etiopathology of amyotrophic lateral sclerosis (ALS). Inflammasomes consist of a pattern recognition receptor (PRR),
Autor:
Philipp Hartmann, Stefan Nikolin, E. Esch, S. Lehmann, Cordian Beyer, Anand Goswami, Joachim Weis, Sonja Johann
Publikováno v:
Neuropathology and Applied Neurobiology. 44:606-627
Aims Amyotrophic lateral sclerosis (ALS) is characterized by degeneration of motoneurons and progressive muscle wasting. Inflammatory processes, mediated by non-neuronal cells, such as glial cells, are known to contribute to disease progression. Infl
Autor:
Gabriele M. Rune, Cordian Beyer, Berthold Debye, Sonja Johann, Lena Hanna Christine Schmülling, Lepu Zhou
Publikováno v:
Brain Pathology. 28:14-27
Nowadays, amyotrophic lateral sclerosis (ALS) is considered as a multisystem disorder, characterized by a primary degeneration of motor neurons as well as neuropathological changes in non-motor regions. Neurodegeneration in subcortical areas, such as
Autor:
Eva Bushuven, Martin Grond, Alice Dreser, Stefan Nikolin, S. Wagner, Priyanka Tripathi, Carsten Drepper, Sonja Johann, Anand Goswami, Istvan Katona, Cordian Beyer, Jasper J. Anink, Christian M. Simon, Dirk Troost, Joachim Weis, Christopher Marvin Jesse, Michael Sendtner, Alfred Yamoah, Akila Chandrasekar
Publikováno v:
Brain Pathology. 27:781-794
Alpha-motoneurons and muscle fibres are structurally and functionally interdependent. Both cell types particularly rely on endoplasmic reticulum (ER/SR) functions. Mutations of the ER proteins VAPB, SigR1 and HSP27 lead to hereditary motor neuron dis
Autor:
Sonja Johann, Marius Heitzer, Cordian Beyer, Mithila Kanagaratnam, Adib Zendedel, Sarah Nele Kaiser, Philipp Hartmann
Publikováno v:
Molecular Neurobiology. 54:8429-8443
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease manifested by the progressive loss of upper and lower motoneurons. The pathomechanism of ALS is complex and not yet fully understood. Neuroinflammation is believed to significan