Výsledky vyhledávání - "Sonja, Gadzovska Simic"

Akademický článek

Regulation of carbohydrate metabolism and insulin secretion in diabetic rats following treatment with Hypericum perforatum L. hairy root aqueous methanol extract

Autor: Elena Rafailovska, Oliver Tusevski, Sonja Gadzovska- Simic, Sasho Panov, Jasmina Petreska Stanoeva, Suzana Dinevska – Kjovkarovska, Biljana Miova

Publikováno v: Macedonian Journal of Chemistry and Chemical Engineering, Vol 43, Iss 1 (2024)

Hairy root (HR) cultures of Hypericum perforatum L. have shown promise in controlling hyperglycemia, regulating blood lipid and enzyme profiles, and improving metabolic function in vivo. These benefits are mainly attributed to the phenolic acids, fla

Externí odkaz: https://doaj.org/article/57f54473e9c546cbaa295372c8ec5bdd

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Akademický článek

Phytochemical Analysis, Biological Activities, and Docking of Phenolics from Shoot Cultures of Hypericum perforatum L. Transformed by Agrobacterium rhizogenes

Autor: Oliver Tusevski, Marija Todorovska, Jasmina Petreska Stanoeva, Sonja Gadzovska Simic

Publikováno v: Molecules, Vol 29, Iss 16, p 3893 (2024)

Hypericum perforatum transformed shoot lines (TSL) regenerated from corresponding hairy roots and non-transformed shoots (NTS) were comparatively evaluated for their phenolic compound contents and in vitro inhibitory capacity against target enzymes (

Externí odkaz: https://doaj.org/article/54636889ad9e45879efa78d0c09c3269

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Akademický článek

Production of Phenylpropanoids, Naphthodianthrones and Antioxidant Status of Hypericum perforatum L. Transgenic Shoots

Autor: Oliver Tusevski, Marija Todorovska, Ivana Todorovska, Jasmina Petreska Stanoeva, Sonja Gadzovska Simic

Publikováno v: Horticulturae, Vol 10, Iss 1, p 59 (2024)

Fifteen transgenic shoot clones (TS A-TS O) regenerated from Hypericum perforatum hairy roots were evaluated for growth characteristics, phenylpropanoid, and naphthodianthrone production, as well as non-enzymatic and enzymatic antioxidant status. Tra

Externí odkaz: https://doaj.org/article/c983bc5150324040b335f44816ee2a4a

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Akademický článek

Hypericum perforatum L. Hairy root extracts – regulation of glycemic, metabolic, serum enzyme and lipid profile in STZ - induced diabetic rats

Autor: Elena Rafailovska, Oliver Tushevski, Sonja Gadzovska - Simic, Suzana Dinevska - Kjovkarovska, Biljana Miova

Publikováno v: Macedonian Veterinary Review, Vol 45, Iss 1, Pp 5-15 (2022)

Apart from currently available therapeutics for the treatment of diabetes mellitus, much attention has been paid to discover phytochemicals from natural resources, mainly due to their low side-effects. Hypericum perforatum hairy root (HR) transformed

Externí odkaz: https://doaj.org/article/a078836261dd41e7acce0693e88a6c26

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Akademický článek

Non-Enzymatic and Enzymatic Antioxidant Responses of Hypericum perforatum L. Hairy Roots upon Photooxidative Stress

Autor: Oliver Tusevski, Sonja Gadzovska Simic

Publikováno v: Horticulturae, Vol 9, Iss 5, p 581 (2023)

The aim of this study was to evaluate the non-enzymatic and enzymatic antioxidant response of fifteen Hypericum perforatum L. dark-grown (HR1 A-HR1 O) and photoperiod-exposed (HR2 A-HR2 O) hairy root clones. Dark-grown HR1 clones were characterized w

Externí odkaz: https://doaj.org/article/86fabcfbfa6b4baf93212c889e6c01a3

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