Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Soniza V Alves-Leon"'
Autor:
Felipe C. Ribeiro, Danielle Cozachenco, Luana Heimfarth, Juliana T. S. Fortuna, Guilherme B. de Freitas, Jorge M. de Sousa, Soniza V. Alves-Leon, Renata E. P. Leite, Claudia K. Suemoto, Lea T. Grinberg, Fernanda G. De Felice, Mychael V. Lourenco, Sergio T. Ferreira
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract The proteasome plays key roles in synaptic plasticity and memory by regulating protein turnover, quality control, and elimination of oxidized/misfolded proteins. Here, we investigate proteasome function and localization at synapses in Alzhei
Externí odkaz:
https://doaj.org/article/bdf4804051b140dd9c552fb96120595a
Autor:
Felipe R. Schmidt, Flavio Henrique R. Costa, Fernanda M.L.C. Silva, Henryk Maultasch, Ana Lucia Rosso, Denise H. Nicaretta, James P. de Mattos, Sergio A.P. Novis, Soniza V Alves-Leon
Publikováno v:
Arquivos de Neuro-Psiquiatria, Vol 70, Iss 4, Pp 271-272 (2012)
Paroxysmal dyskinesias (PD) are thought to be rare movement disorders. The overwhelming majority of reported cases are primary. Secondary PD has seen reported to occur in some conditions, mainly in multiple sclerosis and head trauma. The anatomic ori
Externí odkaz:
https://doaj.org/article/c396977ac6474ff2a323ba74acf273a6
Autor:
Diogo G. Corrêa, Eelco van Duinkerken, João Gabriel D. Farinhas, Valéria C. Pereira, Emerson L. Gasparetto, Soniza V. Alves-Leon, Fernanda Cristina R. Lopes
Publikováno v:
Journal of Central Nervous System Disease, Vol 15 (2023)
Background Changes in brain connectivity occur in patients with multiple sclerosis (MS), even in patients under disease-modifying therapies. Using magnetic resonance imaging (MRI) to asses patients treated with disease-modifying therapies, such as na
Externí odkaz:
https://doaj.org/article/da201211e96f426ea6ac32a02c122dc0
Autor:
Fabricia L. Fontes-Dantas, Gabriel G. Fernandes, Elisa G. Gutman, Emanuelle V. De Lima, Leticia S. Antonio, Mariana B. Hammerle, Hannah P. Mota-Araujo, Lilian C. Colodeti, Suzana M.B. Araújo, Gabrielle M. Froz, Talita N. da Silva, Larissa A. Duarte, Andreza L. Salvio, Karina L. Pires, Luciane A.A. Leon, Claudia Cristina F. Vasconcelos, Luciana Romão, Luiz Eduardo B. Savio, Jerson L. Silva, Robson da Costa, Julia R. Clarke, Andrea T. Da Poian, Soniza V. Alves-Leon, Giselle F. Passos, Claudia P. Figueiredo
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112189- (2023)
Summary: Cognitive dysfunction is often reported in patients with post-coronavirus disease 2019 (COVID-19) syndrome, but its underlying mechanisms are not completely understood. Evidence suggests that severe acute respiratory syndrome coronavirus 2 (
Externí odkaz:
https://doaj.org/article/fe134363e486421c960c5fd3b4c479bc
Autor:
Nathalia Müller, Mateus Eugenio, Luciana F. Romão, Jorge Marcondes de Souza, Soniza V. Alves‐Leon, Loraine Campanati, Celso Sant’Anna
Publikováno v:
IET Nanobiotechnology, Vol 15, Iss 6, Pp 558-564 (2021)
Abstract Glioblastoma is the most life‐threatening tumour of the central nervous system. Temozolomide (TMZ) is the first‐choice oral drug for the treatment of glioblastoma, although it shows low efficacy. Silver nanoparticles (AgNPs) have been sh
Externí odkaz:
https://doaj.org/article/64815b2e4a524c5d9d6fd29ec585f2bf
Autor:
Claudia P. Figueiredo, Fernanda G. Q. Barros-Aragão, Rômulo L. S. Neris, Paula S. Frost, Carolina Soares, Isis N. O. Souza, Julianna D. Zeidler, Daniele C. Zamberlan, Virginia L. de Sousa, Amanda S. Souza, André Luis A. Guimarães, Maria Bellio, Jorge Marcondes de Souza, Soniza V. Alves-Leon, Gilda A. Neves, Heitor A. Paula-Neto, Newton G. Castro, Fernanda G. De Felice, Iranaia Assunção-Miranda, Julia R. Clarke, Andrea T. Da Poian, Sergio T. Ferreira
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Here, using ex-vivo human adult cortical tissue and a mouse model, the authors investigate the functional consequences of Zika virus (ZIKV) infection in the adult brain, and show that ZIKV causes synapse damage and altered brain function that impacts
Externí odkaz:
https://doaj.org/article/0bac999998154571acca058da9d921c8
Autor:
JULIANA M. SOARES, BRUNA M. DE FARIA, LUCAS M. ASCARI, SONIZA V. ALVES-LEON, JORGE M. DE SOUZA, ANTONIO G. SOARES, YRAIMA CORDEIRO, LUCIANA F. ROMÃO
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 91, Iss 4 (2019)
Abstract: Diosmin is a flavone glycoside clinically used as the main component of Daflon for the treatment of venous diseases. Several studies demonstrated that this natural compound can induce apoptosis in different tumors. However, isolated diosmin
Externí odkaz:
https://doaj.org/article/0bc6b812992147bfb00c578bfa29ae86
Autor:
Jéssica Gonçalves Pereira, Luciane A. Amado Leon, Nathalia Alves Araújo de Almeida, Jéssica Vasques Raposo-Vedovi, Fabrícia Lima Fontes-Dantas, João Gabriel Dib Farinhas, Valéria Coelho Santa Rita Pereira, Soniza V. Alves-Leon, Vanessa S. de Paula
Publikováno v:
Multiple Sclerosis and Related Disorders. :104747
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52b72c6e46bc1bc441d91d55a1845906
https://doi.org/10.1016/j.msard.2023.104747
https://doi.org/10.1016/j.msard.2023.104747
Autor:
Fabricia L. Fontes-Dantas, Gabriel G. Fernandes, Elisa G. Gutman, Emanuelle V. De Lima, Leticia S. Antonio, Mariana B. Hammerle, Hannah P. Mota-Araujo, Lilian C. Colodeti, Suzana M. B. Araújo, Talita N. da Silva, Larissa A. Duarte, Andreza L. Salvio, Karina L. Pires, Luciane A. A. Leon, Claudia Cristina F. Vasconcelos, Luciana Romão, Luiz Eduardo B. Savio, Jerson L. Silva, Robson da Costa, Julia R. Clarke, Andrea T. Da Poian, Soniza V. Alves-Leon, Giselle F. Passos, Claudia P. Figueiredo
Cognitive dysfunction is often reported in post-COVID patients, but its underlying mechanisms remain unknown. While some evidence indicate that SARS-CoV-2 can reach and directly impact the brain, others suggest viral neuroinvasion as a rare event. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c0339e927cbaa9c7540b83589ff021e
https://doi.org/10.1101/2022.06.07.495149
https://doi.org/10.1101/2022.06.07.495149
Autor:
Thais B, Ferreira, Joana, Hygino, Ana Cristina, Wing, Taissa M, Kasahara, Priscila M, Sacramento, Solange, Camargo, Fernanda, Rueda, Soniza V, Alves-Leon, Regina, Alvarenga, Claudia Cristina, Vasconcelos, Anshu, Agrawal, Sudhir, Gupta, Cleonice A M, Bento
Publikováno v:
Immunology. 154(2)
Signalling through Toll‐like receptors (TLRs) may play a role in the pathogenesis of autoimmune diseases, such as multiple sclerosis (MS). In the present study, the expression of TLR‐2, ‐4 and ‐9 was significantly higher on CD4(+) and CD8(+)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::62cddbdb93799bb11066b41972f1840f
https://pubmed.ncbi.nlm.nih.gov/29168181
https://pubmed.ncbi.nlm.nih.gov/29168181